2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase 1 ; Homo sapiens







1260 Article(s)
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1 33999413 Porphyromonas gingivalis lipopolysaccharide and gingival fibroblast augment MMP-9 expression of monocytic U937 cells through cyclophilin A. 2022 Mar 1
2 34730869 ROS generation is involved in titanium dioxide nanoparticle-induced AP-1 activation through p38 MAPK and ERK pathways in JB6 cells. 2022 Feb 1
3 34748972 Endothelin-1 induces lipolysis through activation of the GC/cGMP/Ca2+/ERK/CaMKIII pathway in 3T3-L1 adipocytes. 2022 Feb 1
4 34864005 Delineation of gastric tumors with activated ERK/MAPK signaling cascades for the development of targeted therapeutics. 2022 Jan 1 1
5 34913072 Knockdown of CCL28 inhibits endometriosis stromal cell proliferation and invasion via ERK signaling pathway inactivation. 2022 Feb 2
6 34971708 Tumor necrosis factor α upregulates the bile acid efflux transporter OATP3A1 via multiple signaling pathways in cholestasis. 2022 Feb 1
7 35069890 Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. 2022 1
8 35078573 [Valproate up-regulates the expression of NKG2DL through the MEK/ERK signaling pathway to enhance the killing effect of NK cells on A375 human melanoma cells]. 2022 Jan 1
9 35142421 Inorganic arsenic promotes apoptosis of human immortal keratinocytes through the TGF-β1/ERK signaling pathway. 2022 Jun 2
10 35237605 Role of Integrin αvβ3 in Doxycycline-Induced Anti-Proliferation in Breast Cancer Cells. 2022 2
11 35294968 Oxidative Stress-induced Autophagy Compromises Stem Cell Viability. 2022 May 27 1
12 35301650 Exogenous interleukin-1 beta promotes the proliferation and migration of HeLa cells via the MEK/ERK signaling pathway. 2022 May 1
13 35523108 LncRNA-CCAT1/miR-152-3p is involved in CSE-induced inflammation in HBE cells via regulating ERK signaling pathway. 2022 Aug 1
14 35563057 Norketamine, the Main Metabolite of Ketamine, Induces Mitochondria-Dependent and ER Stress-Triggered Apoptotic Death in Urothelial Cells via a Ca2+-Regulated ERK1/2-Activating Pathway. 2022 Apr 23 1
15 33003239 Curcumin Promotes Collagen Type I, Keratinocyte Growth Factor-1, and Epidermal Growth Factor Receptor Expressions in the In Vitro Wound Healing Model of Human Gingival Fibroblasts. 2021 Feb 2
16 33169892 RICK regulates the odontogenic differentiation of dental pulp stem cells through activation of TNF-α via the ERK and not through NF-κB signaling pathway. 2021 Mar 1
17 33242203 Extracellular Vesicles Derived from Intermittent Hypoxia-Treated Red Blood Cells Impair Endothelial Function Through Regulating eNOS Phosphorylation and ET-1 Expression. 2021 Oct 1
18 33290316 A PI3K inhibitor-induced growth inhibition of cancer cells is linked to MEK-ERK pathway. 2021 Jun 1 1
19 33526070 Human keratinocyte-derived extracellular vesicles activate the MAPKinase pathway and promote cell migration and proliferation in vitro. 2021 Feb 2 2
20 33552829 MiR-192-5p regulates the proliferation and apoptosis of cholangiocarcinoma cells by activating MEK/ERK pathway. 2021 Feb 1
21 33731247 Erratum. 2021 Mar 16 1
22 33747807 Effect of zymosan on the expression and function of the gap-junction protein connexin 43 in human corneal fibroblasts. 2021 2
23 33784561 BarH-like homeobox 1 induces the progression of cell malignant phenotype in endometrial carcinoma through the regulation of ERK/MEK signaling pathway. 2021 Jun 2
24 34051057 Activation of the mitogen-activated protein kinase ERK1/2 signaling pathway suppresses the expression of ChREBPα and β in HepG2 cells. 2021 Jul 1
25 34066541 Activated ERK Signaling Is One of the Major Hub Signals Related to the Acquisition of Radiotherapy-Resistant MDA-MB-231 Breast Cancer Cells. 2021 May 6 3
26 34160728 miR-483-3p Promotes IL-33 Production from Fibroblast-Like Synoviocytes by Regulating ERK Signaling in Rheumatoid Arthritis. 2021 Dec 1
27 34184076 TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway. 2021 Aug 2
28 34362478 [Effect of Petroleum Ether Extract of Rhizoma Amorphophalli on Biological Characteristics of K562 Cells and Its Mechanism]. 2021 Aug 1
29 34514104 Helicobacter pylori promotes gastric cancer progression by upregulating semaphorin 5A expression via ERK/MMP9 signaling. 2021 Sep 24 1
30 34576317 Wound Healing Effect of Gintonin Involves Lysophosphatidic Acid Receptor/Vascular Endothelial Growth Factor Signaling Pathway in Keratinocytes. 2021 Sep 21 1
31 34638875 Combination of PD98059 and TGF-β1 Efficiently Differentiates Human Urine-Derived Stem Cells into Smooth Muscle Cells. 2021 Sep 29 2
32 34670665 [Cisplatin promotes PD-L1 expression in A549 human lung adenocarcinoma cells via activating the ERK pathway]. 2021 Oct 2
33 34716498 Increased Expression of CD95 in CD4+ Effector Memory T Cells Promotes Th17 Response in Patients with Myasthenia Gravis. 2021 Oct 29 1
34 35111045 An ApoA-I Mimic Peptide of 4F Promotes SDF-1α Expression in Endothelial Cells Through PI3K/Akt/ERK/HIF-1α Signaling Pathway. 2021 2
35 31498440 Glycochenodeoxycholate induces cell survival and chemoresistance via phosphorylation of STAT3 at Ser727 site in HCC. 2020 Mar 1
36 31643092 BZW2 promotes the malignant progression of colorectal cancer via activating the ERK/MAPK pathway. 2020 May 2
37 31667838 CXCL3 overexpression promotes the tumorigenic potential of uterine cervical cancer cells via the MAPK/ERK pathway. 2020 May 1
38 31809793 Bisdemethoxycurcumin promotes apoptosis in human platelets via activation of ERK signaling pathway. 2020 Mar 1
39 31938969 Human umbilical cord mesenchymal stem cells alleviate inflammatory bowel disease by inhibiting ERK phosphorylation in neutrophils. 2020 Apr 1
40 31951023 TRIM59, amplified in ovarian cancer, promotes tumorigenesis through the MKP3/ERK pathway. 2020 Nov 1
41 32031702 MUC15 promotes growth and invasion of glioma cells by activating Raf/MEK/ERK pathway. 2020 Jun 1
42 32054305 Glycyrrhizic Acid Modulates Apoptosis through Extrinsic/Intrinsic Pathways and Inhibits Protein Kinase B- and Extracellular Signal-Regulated Kinase-Mediated Metastatic Potential in Hepatocellular Carcinoma In Vitro and In Vivo. 2020 1
43 32134157 EGFR-ERK pathway regulates CSN6 to contribute to PD-L1 expression in glioblastoma. 2020 May 1
44 32166572 NDRG4 Alleviates Aβ1-40 Induction of SH-SY5Y Cell Injury via Activation of BDNF-Inducing Signalling Pathways. 2020 Jul 1
45 32277496 DNAJA4 deficiency augments hyperthermia-induced Clusterin and ERK activation: two critical protective factors of human keratinocytes from hyperthermia-induced injury. 2020 Oct 1
46 32319644 Spred2 inhibits epithelial‑mesenchymal transition of colorectal cancer cells by impairing ERK signaling. 2020 Jul 2
47 32468028 The TLR4/ERK/PD‑L1 axis may contribute to NSCLC initiation. 2020 Aug 1
48 32471717 Heat stress induces RIP1/RIP3-dependent necroptosis through the MAPK, NF-κB, and c-Jun signaling pathways in pulmonary vascular endothelial cells. 2020 Jul 12 1
49 32623775 IGFBP5 enhances the dentinogenesis potential of dental pulp stem cells via JNK and ErK signalling pathways. 2020 Dec 1
50 32749897 Chemokine C-C motif ligand 2 suppressed the growth of human brain astrocytes under Ischemic/hypoxic conditions via regulating ERK1/2 pathway. 2020 Jul 28 1