60 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 21674991 | A correction to the research article titled: "Amplification of the driving oncogene, KRAS or BRAF, underpins acquired resistance to MEK1/2 inhibitors in colorectal cancer cells" by A. S. Little, K. Balmanno, M. J. Sale, S. Newman, J. R. Dry, M. Hampson, P. A. W. Edwards, P. D. Smith, S. J. Cook. | 2011 | 1 |
52 | 19910069 | AZD6244 enhances the anti-tumor activity of sorafenib in ectopic and orthotopic models of human hepatocellular carcinoma (HCC). | 2010 Jan | 1 |
53 | 20101735 | AZD6244 (ARRY-142886) enhances the antitumor activity of rapamycin in mouse models of human hepatocellular carcinoma. | 2010 Mar 1 | 1 |
54 | 20103661 | Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders. | 2010 Feb 1 | 1 |
55 | 21098728 | BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation. | 2010 Nov 23 | 3 |
56 | 19548087 | Inhibition of MEK signaling enhances the ability of cytarabine to induce growth arrest and apoptosis of acute myelogenous leukemia cells. | 2009 Sep | 1 |
57 | 19783898 | High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886). | 2009 Nov | 1 |
58 | 18632602 | Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma. | 2008 Jul 15 | 1 |
59 | 18676837 | BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins. | 2008 Aug 1 | 2 |
60 | 17878251 | Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244. | 2007 Dec | 2 |