Wortmannin

mitogen-activated protein kinase 1 ; Homo sapiens







71 Article(s)
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Pub. Year
#Total Relationships
1 28395342 Stimulatory effects of fibroblast growth factor 2 on proliferation and migration of uterine luminal epithelial cells during early pregnancy. 2017 Jan 1 1
2 26657209 Identification of intracellular pathways through which TGF-β1 upregulates URG-4/URGCP gene expression in hepatoma cells. 2016 Jan 1 1
3 26923291 SIRT1 mediates Sphk1/S1P-induced proliferation and migration of endothelial cells. 2016 May 1
4 27456341 Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signaling pathways. 2016 Jul 26 1
5 25858425 Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β. 2015 Jun 1
6 24450273 CXCL12-CXCR7 signaling activates ERK and Akt pathways in human choriocarcinoma cells. 2014 Aug 1
7 21358682 G-CSF downregulates natural killer cell-mediated cytotoxicity in donors for hematopoietic SCT. 2012 Jan 1
8 22879882 PI3K contributed to modulation of spinal nociceptive information related to ephrinBs/EphBs. 2012 1
9 23300886 Leptin induces cyclin D1 expression and proliferation of human nucleus pulposus cells via JAK/STAT, PI3K/Akt and MEK/ERK pathways. 2012 1
10 22077956 Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr. 2011 Nov 11 1
11 19800362 The sensing of essential amino acid deficiency in the anterior piriform cortex, that requires the uncharged tRNA/GCN2 pathway, is sensitive to wortmannin but not rapamycin. 2010 Jan 1
12 19906641 Resolvin E1 receptor activation signals phosphorylation and phagocytosis. 2010 Jan 29 1
13 19917268 Angiogenic activity of sesamin through the activation of multiple signal pathways. 2010 Jan 1 1
14 20008963 A polysaccharide, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart. 2010 Jan 1
15 20402656 Cytotoxicity of a vanadyl(IV) complex with a multidentate oxygen donor in osteoblast cell lines in culture. 2010 Jan 1
16 20471474 PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells. 2010 Sep 1
17 20512938 Role of ERK1/2 in platelet lysate-driven endothelial cell repair. 2010 Jun 1 1
18 18256541 Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells. 2008 Mar 1 1
19 18515984 Intracellular signaling pathways regulate hormone-dependent kallikrein gene expression. 2008 1
20 18953090 Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons. 2008 Sep 2
21 17222412 Involvement of phosphatidylinositol-3-kinase and ERK pathways in the production of TGF-beta1 by macrophages treated with liposomes composed of phosphatidylserine. 2007 Jan 23 1
22 17303087 Nrf2 is involved in the effect of tanshinone IIA on intracellular redox status in human aortic smooth muscle cells. 2007 May 1 1
23 17308073 Combination of sublethal concentrations of epidermal growth factor receptor inhibitor and microtubule stabilizer induces apoptosis of glioblastoma cells. 2007 Feb 1
24 17464189 Lactosylceramide alpha2,3-sialyltransferase is induced via a PKC/ERK/CREB-dependent pathway in K562 human leukemia cells. 2007 Apr 30 1
25 17643958 Activation of calcium-dependent kinases and epidermal growth factor receptor regulate muscarinic acetylcholine receptor-mediated MAPK/ERK activation in thyroid epithelial cells. 2007 Oct 1
26 17724683 Distinct signaling mechanisms activate the target of rapamycin in response to different B-cell stimuli. 2007 Oct 1
27 17878755 Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduction pathway. 2007 Sep 1
28 16458614 Notoginsenoside R1 from Panax notoginseng inhibits TNF-alpha-induced PAI-1 production in human aortic smooth muscle cells. 2006 Apr 3
29 16641198 The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. 2006 Jun 1
30 16914897 P2Y receptors activate MAPK/ERK through a pathway involving PI3K/PDK1/PKC-zeta in human vein endothelial cells. 2006 1
31 15572039 Low proliferation and high apoptosis of osteoblastic cells on hydrophobic surface are associated with defective Ras signaling. 2005 Feb 1 1
32 15744749 Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells. 2005 Aug 1
33 16100051 Cell-signaling evidence for adenosine stimulation of coronary smooth muscle proliferation via the A1 adenosine receptor. 2005 Sep 16 1
34 14660637 Direct interaction of major histocompatibility complex class II-derived peptides with class Ia phosphoinositide 3-kinase results in dose-dependent stimulatory effects. 2004 Feb 27 2
35 14705145 Retinoic acid-induced neuritogenesis of human neuroblastoma SH-SY5Y cells is ERK independent and PKC dependent. 2004 Jan 15 1
36 15110780 Salivary phospholipid secretion in response to beta-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation. 2004 May 21 2
37 15177934 Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells. 2004 Aug 15 1
38 15194438 Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells. 2004 Jul 1 1
39 15492467 Cytochrome c release from oridonin-treated apoptotic A375-S2 cells is dependent on p53 and extracellular signal-regulated kinase activation. 2004 Oct 1
40 12681450 IL-2 activation of a PI3K-dependent STAT3 serine phosphorylation pathway in primary human T cells. 2003 Jun 1
41 12942541 PKC-zeta is required for angiotensin II-induced activation of ERK and synthesis of C-FOS in MCF-7 cells. 2003 Oct 1
42 12943808 Sphingosine-1-phosphate stimulates smooth muscle cell migration through galpha(i)- and pi3-kinase-dependent p38(MAPK) activation. 2003 Jul 1
43 14516797 The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. 2003 Oct 15 1
44 14563359 Distinct LPS-induced signals regulate LPS uptake and morphological changes in medfly hemocytes. 2003 Nov 1
45 11994364 Mitogen-activated protein kinase cascade in human normal and tumoral parathyroid cells. 2002 May 1
46 12055097 Phosphatidylinositol 3-kinase-dependent, MEK- independent proliferation in response to CaR activation. 2002 Jul 3
47 12296652 Evidence for phosphatidylinositol 3-kinase-Akt-p7S6K pathway activation and transduction of mitogenic signals by platelet-derived growth factor in meningioma cells. 2002 Sep 2
48 12444151 Macrophage-colony-stimulating factor-induced activation of extracellular-regulated kinase involves phosphatidylinositol 3-kinase and reactive oxygen species in human monocytes. 2002 Dec 1 4
49 11241670 The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells. 2001 Mar 26 1
50 11445586 An inhibitory role of the phosphatidylinositol 3-kinase-signaling pathway in vascular endothelial growth factor-induced tissue factor expression. 2001 Sep 7 1