SB 203580

mitogen-activated protein kinase 1 ; Homo sapiens







496 Article(s)
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151 23149874 Nicotine induces the expression of C-reactive protein via MAPK-dependent signal pathway in U937 macrophages. 2012 Nov 1
152 23182046 Quinuclidinone derivative 6 induced apoptosis in human breast cancer cells via sphingomyelinase and JNK signaling. 2012 Oct 1
153 23257429 [Increasing sensitivity of leukemia cells to imatinib by inhibiting NHE1 and p38MAPK signaling pathway]. 2012 Dec 1
154 20667012 4-Hydroxy-2-nonenal upregulates and phosphorylates cytosolic phospholipase A(2) in cultured Ra2 microglial cells via MAPK pathways. 2011 Apr 1
155 20959155 Formononetin accelerates wound repair by the regulation of early growth response factor-1 transcription factor through the phosphorylation of the ERK and p38 MAPK pathways. 2011 Jan 1
156 21082355 Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism. 2011 Feb 1
157 21177635 Vibrio parahaemolyticus infection induces modulation of IL-8 secretion through dual pathway via VP1680 in Caco-2 cells. 2011 Feb 15 1
158 21212516 Silibinin activated p53 and induced autophagic death in human fibrosarcoma HT1080 cells via reactive oxygen species-p38 and c-Jun N-terminal kinase pathways. 2011 1
159 21219922 Cadmium induces phosphorylation and stabilization of c-Fos in HK-2 renal proximal tubular cells. 2011 Mar 15 1
160 21251657 TGF-β1 diminishes collagen production during long-term cyclic stretching of engineered connective tissue: implication of decreased ERK signaling. 2011 Mar 15 2
161 21257914 Pulsatile to-fro flow induces greater and sustained expression of tissue factor RNA in HUVEC than unidirectional laminar flow. 2011 Apr 1
162 21317307 Atorvastatin suppresses LPS-induced rapid upregulation of Toll-like receptor 4 and its signaling pathway in endothelial cells. 2011 May 1
163 21468925 Attenuated expression and function of the RECK tumor suppressor under hypoxic conditions is mediated by the MAPK signaling pathways. 2011 Jan 1
164 21503966 Cigarette smoke-induced skeletal muscle atrophy is associated with up-regulation of USP-19 via p38 and ERK MAPKs. 2011 Sep 1
165 21574189 Silibinin inhibits the invasion and migration of renal carcinoma 786-O cells in vitro, inhibits the growth of xenografts in vivo and enhances chemosensitivity to 5-fluorouracil and paclitaxel. 2011 Oct 1
166 21600278 p38 MAPK activation is required for esculetin-induced inhibition of vascular smooth muscle cells proliferation. 2011 Oct 1
167 21619869 AMPK induces MUC5B expression via p38 MAPK in NCI-H292 airway epithelial cells. 2011 Jun 17 1
168 21630016 Defective nuclear translocation of stress-activated signaling in senescent diploid human fibroblasts: a possible explanation for aging-associated apoptosis resistance. 2011 Aug 2
169 21637924 Tetramethylpyrazine inhibits migration of SKOV3 human ovarian carcinoma cells and decreases the expression of interleukin-8 via the ERK1/2, p38 and AP-1 signaling pathways. 2011 Sep 1
170 21647617 Effects of downregulation of aquaporin1 by peptidoglycan and lipopolysaccharide via MAPK pathways in MeT-5A cells. 2011 Aug 1
171 21687949 Tubeimoside I sensitizes cisplatin in cisplatin-resistant human ovarian cancer cells (A2780/DDP) through down-regulation of ERK and up-regulation of p38 signaling pathways. 2011 Sep-Oct 1
172 21747198 A uremic solute, P-cresol, inhibits the proliferation of endothelial progenitor cells via the p38 pathway. 2011 1
173 21807062 Vitamin A (retinol) up-regulates the receptor for advanced glycation endproducts (RAGE) through p38 and Akt oxidant-dependent activation. 2011 Oct 28 1
174 21889036 Hemeoxygenase-1 expression in response to arecoline-induced oxidative stress in human umbilical vein endothelial cells. 2011 Sep 1 1
175 21907163 Distinct regulation of mitogen-activated protein kinase activities is coupled with enhanced cardiac differentiation of human embryonic stem cells. 2011 Nov 3
176 21983652 Regulation of heat shock protein 27 phosphorylation during microcystin-LR-induced cytoskeletal reorganization in a human liver cell line. 2011 Dec 15 1
177 21995813 Erythroid differentiation regulator 1 (Erdr1) is a proapototic factor in human keratinocytes. 2011 Nov 1
178 22033475 Antimetastatic effect and mechanism of ovatodiolide in MDA-MB-231 human breast cancer cells. 2011 Nov 15 1
179 22111577 Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways. 2011 Dec 27 1
180 19699794 Activation of ERK1/2 by protein kinase C-alpha in response to hydrogen peroxide-induced cell death in human gingival fibroblasts. 2010 Feb 1
181 20103766 Induction of neutrophil degranulation by S100A9 via a MAPK-dependent mechanism. 2010 May 1
182 20155832 ERK-1/2 and p38 in the regulation of hypertrophic changes of normal articular cartilage chondrocytes induced by osteoarthritic subchondral osteoblasts. 2010 May 1
183 20226460 Palmitic acid promotes endothelial progenitor cells apoptosis via p38 and JNK mitogen-activated protein kinase pathways. 2010 May 1
184 20304034 Galactose specific adhesin of enteroaggregative E. coli induces IL-8 secretion via activation of MAPK and STAT-3 in INT-407 cells. 2010 Jun 1
185 20307495 Hypoxia-induced Bcl-2 expression in endothelial cells via p38 MAPK pathway. 2010 Apr 16 1
186 20373469 Role of mitogen-activated protein kinase in Zn-BC-AM PDT-induced apoptosis in nasopharyngeal carcinoma cells. 2010 Apr 1
187 20380623 Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro, and its toxicity is mediated by p38. 2010 Jun 1
188 20402964 Astrocytic activation and an inhibition of MAP kinases are required for proteinase-activated receptor-2-mediated protection from neurotoxicity. 2010 Jun 1
189 20453870 Myosin light chain kinase is responsible for high proliferative ability of breast cancer cells via anti-apoptosis involving p38 pathway. 2010 Jun 2
190 20512938 Role of ERK1/2 in platelet lysate-driven endothelial cell repair. 2010 Jun 1 1
191 20562007 Signal transduction pathways associated with ATP-induced proliferation of colon adenocarcinoma cells. 2010 Sep 1
192 20610539 Hydrogen peroxide mediates EGF-induced down-regulation of E-cadherin expression via p38 MAPK and snail in human ovarian cancer cells. 2010 Aug 1
193 20615389 Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy. 2010 Nov 1 1
194 20731619 Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust. 2010 Oct-Dec 2
195 20736797 Protective effect of P188 in the model of acute trauma to human ankle cartilage: the mechanism of action. 2010 Sep 1
196 20798501 Growth/differentiation factor-5 induces osteogenic differentiation of human ligamentum flavum cells through activation of ERK1/2 and p38 MAPK. 2010 1
197 18982426 Quercetin inhibits IL-1 beta-induced ICAM-1 expression in pulmonary epithelial cell line A549 through the MAPK pathways. 2009 Sep 1
198 19013215 Reactive oxygen species production and MAPK activation are implicated in tetrahydrobiopterin-induced SH-SY5Y cell death. 2009 Jan 16 1
199 19138820 p38 MAP kinase controls EGF receptor downregulation via phosphorylation at Ser1046/1047. 2009 May 8 1
200 19195868 Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK. 2009 Dec 1