SB 203580

mitogen-activated protein kinase 1 ; Homo sapiens







496 Article(s)
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1 34730869 ROS generation is involved in titanium dioxide nanoparticle-induced AP-1 activation through p38 MAPK and ERK pathways in JB6 cells. 2022 Feb 1
2 35100937 2-(Naphthalene-2-thio)-5,8-dimethoxy-1,4-naphthoquinone induces apoptosis via ROS-mediated MAPK, AKT, and STAT3 signaling pathways in HepG2 human hepatocellular carcinoma cells. 2022 Jan 1
3 32500755 Naringin inhibits titanium particles-induced up-regulation of TNF-α and IL-6 via the p38 MAPK pathway in fibroblasts from hip periprosthetic membrane. 2021 Sep 1
4 32924599 Dark Sweet Cherry (Prunus avium) Phenolics Enriched in Anthocyanins Induced Apoptosis in MDA-MB-453 Breast Cancer Cells through MAPK-Dependent Signaling and Reduced Invasion via Akt and PLCγ-1 Downregulation. 2021 2
5 33895548 Estrogen activates endothelial exocytosis. 2021 Jun 18 1
6 34073773 GO-Y078, a Curcumin Analog, Induces Both Apoptotic Pathways in Human Osteosarcoma Cells via Activation of JNK and p38 Signaling. 2021 May 24 1
7 34199278 Combined Effect of Deoxynivalenol (DON) and Porcine Circovirus Type 2 (Pcv2) on Inflammatory Cytokine mRNA Expression. 2021 Jun 13 1
8 34204188 Inhibition of p38 Mitogen-Activated Protein Kinase Impairs Mayaro Virus Replication in Human Dermal Fibroblasts and HeLa Cells. 2021 Jun 17 1
9 34716498 Increased Expression of CD95 in CD4+ Effector Memory T Cells Promotes Th17 Response in Patients with Myasthenia Gravis. 2021 Oct 29 2
10 34769253 Activation of ERK and p38 Reduces AZD8055-Mediated Inhibition of Protein Synthesis in Hepatocellular Carcinoma HepG2 Cell Line. 2021 Oct 30 1
11 31916385 Cantharidic acid induces apoptosis in human nasopharyngeal carcinoma cells through p38-mediated upregulation of caspase activation. 2020 May 1
12 32716065 Interleukin-25 regulates matrix metalloproteinase-2 and -9 expression in periodontal fibroblast cells through ERK and P38MAPK pathways. 2020 Nov 2
13 32744597 TRIM59 Promotes Retinoblastoma Progression by Activating the p38-MAPK Signaling Pathway. 2020 Aug 3 1
14 32851798 Lactate induced up-regulation of KLHDC8A (Kelch domain-containing 8A) contributes to the proliferation, migration and apoptosis of human glioma cells. 2020 Oct 1
15 33013353 Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca+2 Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells. 2020 1
16 30246289 Tannic acid protects against experimental acute lung injury through downregulation of TLR4 and MAPK. 2019 May 2
17 30461130 Extracellular matrix remodeling effects of serum amyloid A1 in the human amnion: Implications for fetal membrane rupture. 2019 Jan 1
18 30502647 Inhibitory effect of berberine on interleukin-2 secretion from PHA-treated lymphocytic Jurkat cells. 2019 Jan 1
19 30801954 Regorefenib induces extrinsic/intrinsic apoptosis and inhibits MAPK/NF-κB-modulated tumor progression in bladder cancer in vitro and in vivo. 2019 Jun 1
20 30824186 Co-crystal structure determination and cellular evaluation of 1,4-dihydropyrazolo[4,3-c] [1,2] benzothiazine 5,5-dioxide p38α MAPK inhibitors. 2019 Apr 9 1
21 30918168 Sustained exposure to prostaglandin D2 augments the contraction induced by acetylcholine via a DP1 receptor-mediated activation of p38 in bronchial smooth muscle of naive mice. 2019 1
22 30983163 Licochalcone A induces apoptotic cell death via JNK/p38 activation in human nasopharyngeal carcinoma cells. 2019 Jul 1
23 31234488 Liquiritin and Liquiritigenin Induce Melanogenesis via Enhancement of p38 and PKA Signaling Pathways. 2019 Jun 22 1
24 31301417 WITHDRAWN: Cinobufagin induced cell apoptosis and protective autophagy through the ROS/MAPK signaling pathway. 2019 Jul 11 1
25 31505816 CLEFMA Activates the Extrinsic and Intrinsic Apoptotic Processes through JNK1/2 and p38 Pathways in Human Osteosarcoma Cells. 2019 Sep 9 1
26 31676320 Increasing ERK phosphorylation by inhibition of p38 activity protects against cadmium-induced apoptotic cell death through ERK/Drp1/p38 signaling axis in spermatocyte-derived GC-2spd cells. 2019 Dec 1 1
27 31831024 The regulatory mechanism of p38/MAPK in the chondrogenic differentiation from bone marrow mesenchymal stem cells. 2019 Dec 12 1
28 29115577 Long non‑coding RNA DANCR regulates the proliferation and osteogenic differentiation of human bone-derived marrow mesenchymal stem cells via the p38 MAPK pathway. 2018 Jan 1
29 29380233 p38 differentially regulates ERK, p21, and mitogenic signalling in two pancreatic carcinoma cell lines. 2018 Dec 1
30 29463296 Nilotinib impairs skeletal myogenesis by increasing myoblast proliferation. 2018 Feb 20 3
31 29620273 p38 inhibitor inhibits the apoptosis of cowanin-treated human colorectal adenocarcinoma cells. 2018 Jun 2
32 29627441 Amentoflavone-induced oxidative stress activates NF-E2-related factor 2 via the p38 MAP kinase-AKT pathway in human keratinocytes. 2018 Jun 1
33 29770357 MAPK Pathway Involved in Epidermal Terminal Differentiation of Normal Human Epidermal Keratinocytes. 2018 1
34 29913201 Methylmercury induces oxidative stress and subsequent neural hyperactivity leading to cell death through the p38 MAPK-CREB pathway in differentiated SH-SY5Y cells. 2018 Jul 1
35 30021550 Recombinant oncolytic Newcastle disease virus displays antitumor activities in anaplastic thyroid cancer cells. 2018 Jul 18 1
36 30073566 Hyperbaric Oxygen Alleviates the Inflammatory Response Induced by LPS Through Inhibition of NF-κB/MAPKs-CCL2/CXCL1 Signaling Pathway in Cultured Astrocytes. 2018 Dec 1
37 30088173 Biglycan, a Nitric Oxide-Downregulated Proteoglycan, Prevents Nitric Oxide-Induced Neuronal Cell Apoptosis via Targeting Erk1/2 and p38 Signaling Pathways. 2018 Sep 1
38 30115376 Different involvement of the MAPK family in inflammatory regulation in human pulmonary microvascular endothelial cells stimulated with LPS and IFN-γ. 2018 Dec 2
39 30300626 Chrysophanol selectively represses breast cancer cell growth by inducing reactive oxygen species production and endoplasmic reticulum stress via AKT and mitogen-activated protein kinase signal pathways. 2018 Dec 1 1
40 28075474 Isomahanine induces endoplasmic reticulum stress and simultaneously triggers p38 MAPK-mediated apoptosis and autophagy in multidrug-resistant human oral squamous cell carcinoma cells. 2017 Feb 1
41 28183201 Effect of titanium dioxide nanoparticles (TiO2 NPs) on the expression of mucin genes in human airway epithelial cells. 2017 Jan 1
42 28393288 Differential effects of p38 MAP kinase inhibitors SB203580 and SB202190 on growth and migration of human MDA-MB-231 cancer cell line. 2017 Aug 4
43 28524116 Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells. 2017 May 18 3
44 28642873 Serum Amyloid A Induces a Vascular Smooth Muscle Cell Phenotype Switch through the p38 MAPK Signaling Pathway. 2017 1
45 28734155 Activation of mTOR is involved in anti-β2GPI/β2GPI-induced expression of tissue factor and IL-8 in monocytes. 2017 Sep 1
46 28990053 P38/ERK MAPK signaling pathways are involved in the regulation of filaggrin and involucrin by IL‑17. 2017 Dec 1
47 29022012 Vanadate oxidative and apoptotic effects are mediated by the MAPK-Nrf2 pathway in layer oviduct magnum epithelial cells. 2017 Nov 15 1
48 25683703 Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells. 2016 May 1
49 26795953 PDGF-BB induces PRMT1 expression through ERK1/2 dependent STAT1 activation and regulates remodeling in primary human lung fibroblasts. 2016 Apr 1
50 26849940 Dioscin suppresses human laryngeal cancer cells growth via induction of cell-cycle arrest and MAPK-mediated mitochondrial-derived apoptosis and inhibition of tumor invasion. 2016 Mar 5 1