| 1 |
32753885 | Chloroquine Combined with Imatinib Overcomes Imatinib Resistance in Gastrointestinal Stromal Tumors by Inhibiting Autophagy via the MAPK/ERK Pathway. | 2020 |
2 |
| 2 |
30396570 | Imatinib mesylate elicits extracellular signal-related kinase (ERK) activation and enhances the survival of γ-irradiated epithelial cells. | 2018 Dec 2 |
6 |
| 3 |
30504658 | [MET/ERK and MET/JNK Pathway Activation Is Involved in BCR-ABL Inhibitor-resistance in Chronic Myeloid Leukemia]. | 2018 |
1 |
| 4 |
28418880 | Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells. | 2017 Jun 13 |
2 |
| 5 |
28842696 | Adhesion to stromal cells mediates imatinib resistance in chronic myeloid leukemia through ERK and BMP signaling pathways. | 2017 Aug 25 |
1 |
| 6 |
28927158 | Regulation of HtrA2 on WT1 gene expression under imatinib stimulation and its effects on the cell biology of K562 cells. | 2017 Sep |
1 |
| 7 |
26893362 | RACK1 overexpression is linked to acquired imatinib resistance in gastrointestinal stromal tumor. | 2016 Mar 22 |
1 |
| 8 |
25673643 | FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors. | 2015 Apr |
4 |
| 9 |
25688862 | Spred2 modulates the erythroid differentiation induced by imatinib in chronic myeloid leukemia cells. | 2015 |
1 |
| 10 |
26186064 | The antileukemia effect of metformin in the Philadelphia chromosome-positive leukemia cell line and patient primary leukemia cell. | 2015 Oct |
1 |
| 11 |
26434776 | Triomics Analysis of Imatinib-Treated Myeloma Cells Connects Kinase Inhibition to RNA Processing and Decreased Lipid Biosynthesis. | 2015 Nov 3 |
2 |
| 12 |
26473951 | Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release. | 2015 |
1 |
| 13 |
23462796 | Imatinib mesilate-induced phosphatidylinositol 3-kinase signalling and improved survival in insulin-producing cells: role of Src homology 2-containing inositol 5'-phosphatase interaction with c-Abl. | 2013 Jun |
1 |
| 14 |
21857502 | Methyl-β-cyclodextrin induces programmed cell death in chronic myeloid leukemia cells and, combined with imatinib, produces a synergistic downregulation of ERK/SPK1 signaling. | 2012 Jan |
1 |
| 15 |
22327338 | c-ABL modulates MAP kinases activation downstream of VEGFR-2 signaling by direct phosphorylation of the adaptor proteins GRB2 and NCK1. | 2012 Jun |
1 |
| 16 |
22467682 | Imatinib triggers mesenchymal-like conversion of CML cells associated with increased aggressiveness. | 2012 Aug |
1 |
| 17 |
22875343 | Raf/MEK/ERK signaling inhibition enhances the ability of dequalinium to induce apoptosis in the human leukemic cell line K562. | 2012 Aug |
1 |
| 18 |
21152856 | Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cells. | 2011 Feb |
2 |
| 19 |
21534915 | Development of a plate-based assay for high-content analysis of individual untethered non-adherent cells. | 2011 Aug |
3 |
| 20 |
21637917 | BCR-ABL- and Ras-independent activation of Raf as a novel mechanism of Imatinib resistance in CML. | 2011 Sep |
5 |
| 21 |
20026060 | Blockade of the ERK or PI3K-Akt signaling pathway enhances the cytotoxicity of histone deacetylase inhibitors in tumor cells resistant to gefitinib or imatinib. | 2010 Jan 22 |
1 |
| 22 |
20153728 | Spred2 is involved in imatinib-induced cytotoxicity in chronic myeloid leukemia cells. | 2010 Mar 19 |
1 |
| 23 |
21098700 | Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC. | 2010 Dec 1 |
2 |
| 24 |
19417143 | Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor. | 2009 May |
1 |
| 25 |
19568437 | ERK2, but not ERK1, mediates acquired and "de novo" resistance to imatinib mesylate: implication for CML therapy. | 2009 Jul 1 |
1 |
| 26 |
17584806 | Imatinib mesylate inhibits in vitro and ex vivo biological responses related to vascular occlusion in giant cell arteritis. | 2008 Nov |
2 |
| 27 |
18240216 | Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts. | 2008 Feb |
1 |
| 28 |
18401414 | Sphingosine kinase-1 is a downstream regulator of imatinib-induced apoptosis in chronic myeloid leukemia cells. | 2008 May |
3 |
| 29 |
18615679 | Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors. | 2008 Oct |
1 |
| 30 |
17203222 | STI571 sensitizes nasopharyngeal carcinoma cells to cisplatin: sustained activation of ERK with improved growth inhibition. | 2007 Feb |
3 |
| 31 |
16575905 | Increased sensitivity to the platelet-derived growth factor (PDGF) receptor inhibitor STI571 in chemoresistant glioma cells is associated with enhanced PDGF-BB-mediated signaling and STI571-induced Akt inactivation. | 2006 Jul |
2 |
| 32 |
17094575 | [The anti-tumoral effect of PI3K inhibitor and MEK inhibitor combined with STI571 on chronic myeloid leukemia cells in a bone marrow stromal cell co-culture system]. | 2006 Oct |
2 |
| 33 |
14755542 | Different roles of p38 MAPK and ERK in STI571-induced multi-lineage differentiation of K562 cells. | 2004 Mar |
6 |
| 34 |
15030167 | Inactivation of ERK accelerates erythroid differentiation of K562 cells induced by herbimycin A and STI571 while activation of MEK1 interferes with it. | 2004 Mar |
3 |
| 35 |
15120940 | Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation of K562 cells. | 2004 Jun |
1 |
| 36 |
15142121 | Phosphatidylinositol-3 kinase inhibitors reproduce the selective antiproliferative effects of imatinib on chronic myeloid leukaemia progenitor cells. | 2004 May |
1 |
| 37 |
15173174 | Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells. | 2004 Jul 30 |
1 |
| 38 |
15517875 | Depsipeptide enhances imatinib mesylate-induced apoptosis of Bcr-Abl-positive cells and ectopic expression of cyclin D1, c-Myc or active MEK abrogates this effect. | 2004 Sep-Oct |
1 |