Dinoprostone

mitogen-activated protein kinase 1 ; Homo sapiens







94 Article(s)
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1 35110422 Porphyromonas gingivalis Gingipains Induce Cyclooxygenase-2 Expression and Prostaglandin E2 Production via ERK1/2-Activated AP-1 (c-Jun/c-Fos) and IKK/NF-κB p65 Cascades. 2022 Mar 1 2
2 35356289 Prostaglandin E2 and Receptors: Insight Into Tumorigenesis, Tumor Progression, and Treatment of Hepatocellular Carcinoma. 2022 2
3 32114020 Bradykinin stimulates prostaglandin E2 release in human skeletal muscular fibroblasts. 2020 May 1 2
4 32227417 Epidermal growth factor-induced COX-2 regulates metastasis of head and neck squamous cell carcinoma through upregulation of angiopoietin-like 4. 2020 Jun 1
5 32303181 Prostaglandin E2 stimulates COX-2 expression via mitogen-activated protein kinase p38 but not ERK in human follicular dendritic cell-like cells. 2020 Apr 17 1
6 32385388 Aberrant expression of the COX2/PGE2 axis is induced by activation of the RAF/MEK/ERK pathway in BRAFV595E canine urothelial carcinoma. 2020 May 8 4
7 32407837 PGE2 deficiency predisposes to anaphylaxis by causing mast cell hyperresponsiveness. 2020 Dec 2
8 33247192 Weak acids induce PGE2 production in human oesophageal cells: novel mechanisms underlying GERD symptoms. 2020 Nov 27 2
9 30367494 PROSTAGLANDIN E2 stimulates cancer-related phenotypes in prostate cancer PC3 cells through cyclooxygenase-2. 2019 May 3
10 31502430 FTY720P Upregulates the Na+/K+ ATPase in HepG2 Cells by Activating S1PR3 and Inducing PGE2 Release. 2019 1
11 31703303 Prostaglandin E2 Induces Skin Aging via E-Prostanoid 1 in Normal Human Dermal Fibroblasts. 2019 Nov 7 1
12 28877882 Mechanotransduction signaling in podocytes from fluid flow shear stress. 2018 Jan 1 2
13 29466417 Epinephrine modulates Na+/K+ ATPase activity in Caco-2 cells via Src, p38MAPK, ERK and PGE2. 2018 1
14 29891646 mPGES-1 (Microsomal Prostaglandin E Synthase-1) Mediates Vascular Dysfunction in Hypertension Through Oxidative Stress. 2018 Aug 1
15 27137893 Prostaglandin E2-Dependent Phosphorylation of RAS Inhibition 1 (RIN1) at Ser 291 and 292 Inhibits Transforming Growth Factor-β-Induced RAS Activation Pathway in Human Synovial Fibroblasts: Role in Cell Migration. 2017 Jan 1
16 27377703 Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells. 2017 Feb 2
17 28197966 Signaling pathway involved in the inhibitory effect of FTY720P on the Na+/K+ ATPase in HepG2 cells. 2017 Dec 3
18 28280524 Reactive Oxygen Species Mediated Prostaglandin E2 Contributes to Acute Response of Epithelial Injury. 2017 3
19 28539604 Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6. 2017 May 24 2
20 28651842 Sulodexide prevents activation of the PLA2/COX-2/VEGF inflammatory pathway in human retinal endothelial cells by blocking the effect of AGE/RAGE. 2017 Oct 15 1
21 28740516 PGE2 Promotes the Migration of Mesenchymal Stem Cells through the Activation of FAK and ERK1/2 Pathway. 2017 1
22 27414656 Decursinol angelate inhibits PGE2-induced survival of the human leukemia HL-60 cell line via regulation of the EP2 receptor and NFκB pathway. 2016 Sep 1
23 27795708 Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate. 2016 1
24 25713071 Cyclic AMP signaling reduces sirtuin 6 expression in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase) pathway. 2015 Apr 10 1
25 25811799 Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia. 2015 Mar 26 1
26 26033830 Randomized phase 2 trial of erlotinib in combination with high-dose celecoxib or placebo in patients with advanced non-small cell lung cancer. 2015 Sep 15 4
27 26394174 C-Jun NH2-Terminal Kinase and p38 Inhibition Suppresses Prostaglandin E2-Stimulated Aromatase and Estrogen Receptor Levels in Human Endometriosis. 2015 Nov 10
28 24561081 Cyclic tensile force up-regulates BMP-2 expression through MAP kinase and COX-2/PGE2 signaling pathways in human periodontal ligament cells. 2014 Apr 15 1
29 24693448 Preventive Effects of a Kampo Medicine, Kakkonto, on Inflammatory Responses via the Suppression of Extracellular Signal-Regulated Kinase Phosphorylation in Lipopolysaccharide-Treated Human Gingival Fibroblasts. 2014 1
30 24760659 PGE2 modulates the transcriptional activity of ERRa in prostate stromal cells. 2014 Dec 3
31 24907113 Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activity. 2014 Aug 1 1
32 24912820 Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma. 2014 Jun 9 2
33 24916702 Phenolcarboxylic acids from medicinal herbs exert anticancer effects through disruption of COX-2 activity. 2014 Sep 25 1
34 25332857 Differential regulation of c-Met signaling pathways for synovial cell function. 2014 1
35 25431425 Prostaglandin E2 reverses curcumin-induced inhibition of survival signal pathways in human colorectal carcinoma (HCT-15) cell lines. 2014 Dec 31 1
36 23064451 Prostaglandin E(2) inhibits proteinase-activated receptor 2-signal transduction through regulation of receptor internalization. 2013 2
37 23494562 Prostaglandin E2 receptor EP1 phosphorylate CREB and mediates MMP2 expression in human cholangiocarcinoma cells. 2013 Jun 5
38 23861370 Autocrine and paracrine mechanisms of prostaglandin E₂ action on trophoblast/conceptus cells through the prostaglandin E₂ receptor (PTGER2) during implantation. 2013 Oct 1
39 21507199 IL-10 production in non-small cell lung carcinoma patients is regulated by ERK, P38 and COX-2. 2012 Mar 1
40 22080750 Prostaglandin E2 enhances interleukin-8 production via EP4 receptor in human pulmonary microvascular endothelial cells. 2012 Jan 15 2
41 22450688 Prostaglandin E2 blocks menadione-induced apoptosis through the Ras/Raf/Erk signaling pathway in promonocytic leukemia cell lines. 2012 Apr 2
42 21778143 Positive feedback loop between prostaglandin E2 and EGF-like factors is essential for sustainable activation of MAPK3/1 in cumulus cells during in vitro maturation of porcine cumulus oocyte complexes. 2011 Nov 3
43 21848814 The WxxxE effector EspT triggers expression of immune mediators in an Erk/JNK and NF-κB-dependent manner. 2011 Dec 1
44 21940623 Prostaglandin E2 induces matrix metalloproteinase 9 expression in dendritic cells through two independent signaling pathways leading to activator protein 1 (AP-1) activation. 2011 Nov 11 4
45 19820419 Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors. 2010 Apr 1
46 20015475 Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK. 2010 Feb 1
47 20093341 Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERalpha pathway in human breast cancer cells. 2010 Apr 1
48 20883667 Analysis of isoform specific ERK signaling on the effects of interleukin-1β on COX-2 expression and PGE2 production in human chondrocytes. 2010 Nov 5 6
49 20890108 The induction of S100p expression by the Prostaglandin E₂ (PGE₂)/EP4 receptor signaling pathway in colon cancer cells. 2010 Nov 15 1
50 19082453 Focal adhesion kinase: important to prostaglandin E2-mediated adhesion, migration and invasion in hepatocellular carcinoma cells. 2009 Jan 3