| 51 |
23192020 | Structure of extracellular signal-regulated kinase 2 in complex with ATP and ADP. | 2012 Dec 1 |
6 |
| 52 |
21413023 | HB-EGF synthesis and release induced by cholesterol depletion of human epidermal keratinocytes is controlled by extracellular ATP and involves both p38 and ERK1/2 signaling pathways. | 2011 Jun |
1 |
| 53 |
21483442 | The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells. | 2011 Jul |
3 |
| 54 |
21494553 | A model of a MAPK•substrate complex in an active conformation: a computational and experimental approach. | 2011 Apr 11 |
1 |
| 55 |
21829637 | Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics. | 2011 |
1 |
| 56 |
22028470 | Large-scale discovery of ERK2 substrates identifies ERK-mediated transcriptional regulation by ETV3. | 2011 Oct 25 |
6 |
| 57 |
22113612 | RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). | 2011 Nov 23 |
1 |
| 58 |
19649663 | Homology modeling and atomic level binding study of Leishmania MAPK with inhibitors. | 2010 Mar |
2 |
| 59 |
20179705 | RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF. | 2010 Mar 18 |
2 |
| 60 |
20232875 | Single-well monitoring of protein-protein interaction and phosphorylation-dephosphorylation events. | 2010 Apr 20 |
1 |
| 61 |
20306284 | A computational workflow for the design of irreversible inhibitors of protein kinases. | 2010 Mar |
1 |
| 62 |
20477948 | P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways. | 2010 Aug |
3 |
| 63 |
20562007 | Signal transduction pathways associated with ATP-induced proliferation of colon adenocarcinoma cells. | 2010 Sep |
4 |
| 64 |
18658095 | ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding. | 2009 Jan |
1 |
| 65 |
19424502 | Interface analysis of the complex between ERK2 and PTP-SL. | 2009 |
1 |
| 66 |
19689374 | Development of extracellular signal-regulated kinase inhibitors. | 2009 |
2 |
| 67 |
18280666 | Functional modulation of the ATP-sensitive potassium channel by extracellular signal-regulated kinase-mediated phosphorylation. | 2008 Mar 18 |
3 |
| 68 |
18434089 | Extracellular ATP activates the PLC/PKC/ERK signaling pathway through the P2Y2 purinergic receptor leading to the induction of early growth response 1 expression and the inhibition of viability in human endometrial stromal cells. | 2008 Jul |
2 |
| 69 |
18463290 | Human biliverdin reductase is an ERK activator; hBVR is an ERK nuclear transporter and is required for MAPK signaling. | 2008 May 13 |
1 |
| 70 |
18490749 | Constitutive ERK MAPK activity regulates macrophage ATP production and mitochondrial integrity. | 2008 Jun 1 |
6 |
| 71 |
18501702 | P2X7 receptor as sensitive flow sensor for ERK activation in osteoblasts. | 2008 Aug 1 |
1 |
| 72 |
18559577 | Advances in the development of cancer therapeutics directed against the RAS-mitogen-activated protein kinase pathway. | 2008 Jun 15 |
4 |
| 73 |
18639636 | Tyrosine hydroxylase phosphorylation increases in response to ATP and neuropeptide Y co-stimulation of ERK2 phosphorylation. | 2008 Jul |
1 |
| 74 |
18676374 | cAMP-responding element-binding protein and c-Ets1 interact in the regulation of ATP-dependent MUC5AC gene expression. | 2008 Oct 3 |
1 |
| 75 |
18835158 | Identification of novel inhibitors of extracellular signal-regulated kinase 2 based on the structure-based virtual screening. | 2008 Oct 15 |
1 |
| 76 |
19105050 | Using Caenorhabditis elegans as a model organism for evaluating extracellular signal-regulated kinase docking domain inhibitors. | 2008 Dec |
1 |
| 77 |
17194451 | Role of a cysteine residue in the active site of ERK and the MAPKK family. | 2007 Feb 16 |
3 |
| 78 |
17284517 | Wound-induced ATP release and EGF receptor activation in epithelial cells. | 2007 Mar 1 |
2 |
| 79 |
17652083 | The complete pathway for ERK2-catalyzed reaction. Evidence for an iso random Bi Bi mechanism. | 2007 Sep 21 |
1 |
| 80 |
17720133 | ATP modulation of mitogen activated protein kinases and intracellular Ca2+ in breast cancer (MCF-7) cells. | 2007 Oct 1 |
1 |
| 81 |
16253958 | A role of p44/42 mitogen-activated protein kinases in formyl-peptide receptor-mediated phospholipase D activity and oxidant production. | 2006 Jan |
1 |
| 82 |
16321972 | Feed forward cycle of hypotonic stress-induced ATP release, purinergic receptor activation, and growth stimulation of prostate cancer cells. | 2006 Mar 3 |
1 |
| 83 |
16341234 | Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation. | 2006 Feb |
1 |
| 84 |
16533496 | Extracellular ATP activates ERK1/ERK2 via a metabotropic P2Y1 receptor in a Ca2+ independent manner in differentiated human skeletal muscle cells. | 2006 May 14 |
2 |
| 85 |
16741950 | Nucleotide receptors stimulation by extracellular ATP controls Hsp90 expression through APE1/Ref-1 in thyroid cancer cells: a novel tumorigenic pathway. | 2006 Oct |
1 |
| 86 |
16781450 | Purinergic signaling and kinase activation for survival in pulmonary oxidative stress and disease. | 2006 Jul 1 |
3 |
| 87 |
16892371 | Comparative analysis of the surface interaction properties of the binding sites of CDK2, CDK4, and ERK2. | 2006 Mar |
1 |
| 88 |
16893669 | Modulation of ERK 1/2 and p38 MAPK signaling pathways by ATP in osteoblasts: involvement of mechanical stress-activated calcium influx, PKC and Src activation. | 2006 |
4 |
| 89 |
16914897 | P2Y receptors activate MAPK/ERK through a pathway involving PI3K/PDK1/PKC-zeta in human vein endothelial cells. | 2006 |
6 |
| 90 |
17000106 | Characterization of ATP-independent ERK inhibitors identified through in silico analysis of the active ERK2 structure. | 2006 Dec 15 |
4 |
| 91 |
15774218 | [ERK1/2 and p38 kinases are important regulators in P2Y receptor-mediated prostate cancer invasion]. | 2005 Jan 12 |
2 |
| 92 |
15964513 | Lung epithelial cells release ATP during ozone exposure: signaling for cell survival. | 2005 Jul 15 |
3 |
| 93 |
15994434 | Signaling pathways involved in adenosine triphosphate-induced endothelial cell barrier enhancement. | 2005 Jul 22 |
1 |
| 94 |
16052566 | Cross-talk among epidermal growth factor, Ap(5)A, and nucleotide receptors causing enhanced ATP Ca(2+) signaling involves extracellular kinase activation in cerebellar astrocytes. | 2005 Sep 15 |
1 |
| 95 |
16139248 | Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex. | 2005 Oct 14 |
2 |
| 96 |
16181551 | [SHP2 and MKP5 in P2Y purinergic receptor-mediated prostate cancer invasion]. | 2005 May |
3 |
| 97 |
16185715 | Hydrogen exchange solvent protection by an ATP analogue reveals conformational changes in ERK2 upon activation. | 2005 Oct 28 |
3 |
| 98 |
14761947 | Extracellular ATP-mediated signaling for survival in hyperoxia-induced oxidative stress. | 2004 Apr 16 |
2 |
| 99 |
15001425 | MEK/MAPK as a signaling element in ATP control of endothelial myosin light chain. | 2004 Apr |
1 |
| 100 |
15003601 | Identifying specific kinase substrates through engineered kinases and ATP analogs. | 2004 Apr |
1 |