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32951587 | The Chemosensitizing Role of Metformin in Anti-Cancer Therapy. | 2021 |
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33524789 | The effects of metformin on autophagy. | 2021 May |
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33652909 | Metformin Increases Survival in Hypopharyngeal Cancer Patients with Diabetes Mellitus: Retrospective Cohort Study and Cell-Based Analysis. | 2021 Feb 26 |
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33788730 | Effect of Metformin in Combination With Trametinib and Paclitaxel on Cell Survival and Metastasis in Melanoma Cells. | 2021 Mar |
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34078517 | Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism. | 2021 Jun 1 |
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34716862 | Synergistic effect of metformin and vemurufenib (PLX4032) as a molecular targeted therapy in anaplastic thyroid cancer: an in vitro study. | 2021 Nov |
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34944598 | Metformin Improves Stemness of Human Adipose-Derived Stem Cells by Downmodulation of Mechanistic Target of Rapamycin (mTOR) and Extracellular Signal-Regulated Kinase (ERK) Signaling. | 2021 Nov 27 |
4 |
| 8 |
31789625 | Metformin mediated microRNA-7 upregulation inhibits growth, migration, and invasion of non-small cell lung cancer A549 cells. | 2020 Apr |
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| 9 |
32248666 | Metformin revert insulin-induced oxaliplatin resistance by activating mitochondrial apoptosis pathway in human colon cancer HCT116 cells. | 2020 Jun |
2 |
| 10 |
32734128 | Antitumor Activity of Combination Therapy with Metformin and Trametinib in Non-Small Cell Lung Cancer Cells. | 2020 Jun |
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33014814 | Metformin Overcomes Acquired Resistance to EGFR TKIs in EGFR-Mutant Lung Cancer via AMPK/ERK/NF-κB Signaling Pathway. | 2020 |
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33126710 | Different Effects of Metformin and A769662 on Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells: Distinct Actions on Mitochondrial Fission and Respiration. | 2020 Oct 28 |
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| 13 |
33489797 | Metformin reverses chemoresistance in non-small cell lung cancer via accelerating ubiquitination-mediated degradation of Nrf2. | 2020 Dec |
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| 14 |
30153063 | Effect of metformin and flutamide on insulin, lipogenic and androgen-estrogen signaling, and cardiometabolic risk in a PCOS-prone metabolic syndrome rodent model. | 2019 Jan 1 |
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| 15 |
30551411 | Metformin inhibits estradiol and progesterone-induced decidualization of endometrial stromal cells by regulating expression of progesterone receptor, cytokines and matrix metalloproteinases. | 2019 Jan |
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30551515 | Metformin increases antitumor activity of MEK inhibitor binimetinib in 2D and 3D models of human metastatic melanoma cells. | 2019 Jan |
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| 17 |
31321352 | Synergistic Enhancement of Paclitaxel-induced Inhibition of Cell Growth by Metformin in Melanoma Cells. | 2019 Jun |
2 |
| 18 |
31348945 | Metformin reduces fibrosis factors in insulin resistant and hypertrophied adipocyte via integrin/ERK, collagen VI, apoptosis, and necrosis reduction. | 2019 Sep 15 |
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| 19 |
31886264 | Role of Metformin on Osteoblast Differentiation in Type 2 Diabetes. | 2019 |
2 |
| 20 |
29285650 | Synergistic cytotoxicity of the dipeptidyl peptidase-IV inhibitor gemigliptin with metformin in thyroid carcinoma cells. | 2018 Feb |
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| 21 |
29351188 | Proangiogenic Effect of Metformin in Endothelial Cells Is via Upregulation of VEGFR1/2 and Their Signaling under Hyperglycemia-Hypoxia. | 2018 Jan 19 |
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29467552 | Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase. | 2018 Feb 21 |
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| 23 |
29630425 | Suppressive effects of metformin on T-helper 1-related chemokines expression in the human monocytic leukemia cell line THP-1. | 2018 Nov |
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| 24 |
29760016 | Diabetes-Induced Cardiomyocyte Passive Stiffening Is Caused by Impaired Insulin-Dependent Titin Modification and Can Be Modulated by Neuregulin-1. | 2018 Jul 20 |
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| 25 |
30023463 | Combination of BEZ235 and Metformin Has Synergistic Effect on Cell Viability in Colorectal Cancer Cells. | 2018 Jun |
2 |
| 26 |
30333878 | Metformin reverses the resistance mechanism of lung adenocarcinoma cells that knocks down the Nrf2 gene. | 2018 Nov |
3 |
| 27 |
27699813 | FOXO3a Expression Regulated by ERK Signaling is Inversely Correlated With Y-Box Binding Protein-1 Expression in Prostate Cancer. | 2017 Feb |
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| 28 |
28230206 | MiRNA-21 mediates the antiangiogenic activity of metformin through targeting PTEN and SMAD7 expression and PI3K/AKT pathway. | 2017 Feb 23 |
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| 29 |
28335557 | ROS Production and ERK Activity Are Involved in the Effects of d-β-Hydroxybutyrate and Metformin in a Glucose Deficient Condition. | 2017 Mar 21 |
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| 30 |
28927780 | Effects of metformin on proliferation and apoptosis of human megakaryoblastic Dami and MEG-01 cells. | 2017 Sep |
2 |
| 31 |
26695692 | Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma. | 2016 |
3 |
| 32 |
26802022 | High efficacy of intravesical treatment of metformin on bladder cancer in preclinical model. | 2016 Feb 23 |
2 |
| 33 |
27424158 | Exenatide and metformin express their anti-inflammatory effects on human monocytes/macrophages by the attenuation of MAPKs and NFκB signaling. | 2016 Oct |
2 |
| 34 |
25846811 | Negative regulation of the LKB1/AMPK pathway by ERK in human acute myeloid leukemia cells. | 2015 Jul |
5 |
| 35 |
26052399 | Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: Role of statins and metformin. | 2015 May 18 |
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| 36 |
26186064 | The antileukemia effect of metformin in the Philadelphia chromosome-positive leukemia cell line and patient primary leukemia cell. | 2015 Oct |
1 |
| 37 |
26391180 | Metformin Increases Sensitivity of Pancreatic Cancer Cells to Gemcitabine by Reducing CD133+ Cell Populations and Suppressing ERK/P70S6K Signaling. | 2015 Sep 22 |
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| 38 |
24446492 | Repositioning therapy for thyroid cancer: new insights on established medications. | 2014 Jun |
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| 39 |
24480115 | Metformin modulates PI3K and GLUT4 expression and Akt/PKB phosphorylation in human endometrial stromal cells after stimulation with androgen and insulin. | 2014 Apr |
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| 40 |
24788596 | Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines. | 2014 Jun |
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| 41 |
25245054 | Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expression. | 2014 Dec |
2 |
| 42 |
25493642 | Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells. | 2014 |
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| 43 |
23462329 | Metformin inhibits the growth of human pancreatic cancer xenografts. | 2013 Jul |
1 |
| 44 |
23607966 | mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK. | 2013 Jul |
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| 45 |
23707609 | Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways. | 2013 Sep 1 |
3 |
| 46 |
23879009 | [Metformin--new treatment strategies for gynecologic neoplasms]. | 2013 |
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| 47 |
21995500 | Inhibition of p42 MAPK using a nonviral vector-delivered siRNA potentiates the anti-tumor effect of metformin in prostate cancer cells. | 2012 Apr |
3 |
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22575507 | Metformin induces differentiation in acute promyelocytic leukemia by activating the MEK/ERK signaling pathway. | 2012 Jun 8 |
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| 49 |
23257425 | [Effect of metformin on acute promyelocytic leukemia cell line NB4 and its mechanism]. | 2012 Dec |
1 |
| 50 |
21619869 | AMPK induces MUC5B expression via p38 MAPK in NCI-H292 airway epithelial cells. | 2011 Jun 17 |
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