epigallocatechin gallate

mitogen-activated protein kinase 1 ; Homo sapiens







85 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35063850 Epigallocatechin 3-gallate: From green tea to cancer therapeutics. 2022 Jun 15 1
2 35140796 The Mechanism Study of Common Flavonoids on Antiglioma Based on Network Pharmacology and Molecular Docking. 2022 3
3 33390545 Epigallocatechin-3-Gallate Suppresses the Expression of TNF-α-Induced MMP-1 via MAPK/ERK Signaling Pathways in Human Dermal Fibroblasts. 2021 4
4 33689882 Epigallocatechin-3-gallate exhibits immunomodulatory effects in human primary T cells. 2021 Apr 23 1
5 31554961 ERK1/2-HNF4α axis is involved in epigallocatechin-3-gallate inhibition of HBV replication. 2020 Feb 1
6 31978263 Epigallocatechin Gallate Induces Upregulation of LDL Receptor via the 67 kDa Laminin Receptor-Independent Pathway in HepG2 Cells. 2020 Apr 2
7 32001222 Epigallocatechin-3-gallate protects Wharton's jelly derived mesenchymal stem cells against in vitro heat stress. 2020 Apr 5 1
8 32818507 EGCG sensitizes chemotherapeutic-induced cytotoxicity by targeting the ERK pathway in multiple cancer cell lines. 2020 Oct 15 4
9 32855668 EGCG induces β-defensin 3 against influenza A virus H1N1 by the MAPK signaling pathway. 2020 Oct 4
10 30858760 Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway. 2019 2
11 31005721 (-)-Epigallocatechin-3-gallate suppresses cigarette smoke-induced inflammation in human cardiomyocytes via ROS-mediated MAPK and NF-κB pathways. 2019 May 2
12 31212946 Mechanisms Underlying the Anti-Depressive Effects of Regular Tea Consumption. 2019 Jun 17 1
13 31934166 ERα36 is an effective target of epigallocatechin-3-gallate in hepatocellular carcinoma. 2019 3
14 29373584 Epigallocatechin-3-gallate confers protection against corticosterone-induced neuron injuries via restoring extracellular signal-regulated kinase 1/2 and phosphatidylinositol-3 kinase/protein kinase B signaling pathways. 2018 2
15 29570987 Role of EGCG in Containing the Progression of Lung Tumorigenesis - A Multistage Targeting Approach. 2018 Apr 2
16 28181408 Epigallocatechin gallate induces an up-regulation of LDL receptor accompanied by a reduction of PCSK9 via the annexin A2-independent pathway in HepG2 cells. 2017 Aug 2
17 28485162 Epigallocatechin gallate inhibits the growth of salivary adenoid cystic carcinoma cells via the EGFR/Erk signal transduction pathway and the mitochondria apoptosis pathway. 2017 1
18 28739640 EGCG ameliorates high-fat- and high-fructose-induced cognitive defects by regulating the IRS/AKT and ERK/CREB/BDNF signaling pathways in the CNS. 2017 Nov 4
19 28844000 Epigallocatechin gallate induces extracellular degradation of amyloid β-protein by increasing neprilysin secretion from astrocytes through activation of ERK and PI3K pathways. 2017 Oct 24 2
20 29061787 (-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways. 2017 Nov 3
21 26848751 The Effect of (-)-Epigallocatechin-3-Gallate on IL-1β Induced IL-8 Expression in Orbital Fibroblast from Patients with Thyroid-Associated Ophthalmopathy. 2016 2
22 27038929 (-)-Epigallocatechin Gallate Inhibits Asymmetric Dimethylarginine-Induced Injury in Human Brain Microvascular Endothelial Cells. 2016 Aug 1
23 27147558 Green tea (-)-epigallocatechin gallate inhibits the growth of human villous trophoblasts via the ERK, p38, AMP-activated protein kinase, and protein kinase B pathways. 2016 Aug 1 5
24 27208402 Green tea (-)-epigallocatechin gallate induced growth inhibition of human placental choriocarcinoma cells. 2016 May 5
25 27323164 Epigallocatechin-3-gallate protects retinal vascular endothelial cells from high glucose stress in vitro via the MAPK/ERK-VEGF pathway. 2016 Jun 10 2
26 27832636 Inhibition of EMMPRIN and MMP-9 Expression by Epigallocatechin-3-Gallate through 67-kDa Laminin Receptor in PMA-Induced Macrophages. 2016 3
27 25625511 EGCG inhibits proliferation, invasiveness and tumor growth by up-regulation of adhesion molecules, suppression of gelatinases activity, and induction of apoptosis in nasopharyngeal carcinoma cells. 2015 Jan 23 2
28 25721086 Upregulation of B-cell translocation gene 2 by epigallocatechin-3-gallate via p38 and ERK signaling blocks cell proliferation in human oral squamous cell carcinoma cells. 2015 May 1 7
29 25746833 (-)-Epigallocatechin-3-gallate inhibits osteosarcoma cell invasiveness by inhibiting the MEK/ERK signaling pathway in human osteosarcoma cells. 2015 3
30 25860284 Combination of erlotinib and EGCG induces apoptosis of head and neck cancers through posttranscriptional regulation of Bim and Bcl-2. 2015 Jul 2
31 24269954 EGCG attenuates pro-inflammatory cytokines and chemokines production in LPS-stimulated L02 hepatocyte. 2014 Jan 1
32 24481129 Epigallocatechin-3-gallate inhibits TF and TNF-α expression induced by the anti-β2GPI/β2GPI complex in human THP-1 cells. 2014 Apr 1
33 24880525 Epigallocatechin-3-gallate inhibits proliferation of human aortic smooth muscle cells via up-regulating expression of mitofusin 2. 2014 Apr 2
34 24967182 Epigallocatechin-3-gallate attenuates lipopolysaccharide-induced inflammation in human retinal endothelial cells. 2014 3
35 25263976 Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent activation of extracellular signal-regulated kinase 1/2 in Jurkat cells. 2014 Sep 1
36 25272043 The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibition. 2014 2
37 22959059 (-)-Epigallocatechin-3-gallate induces apoptosis in human endometrial adenocarcinoma cells via ROS generation and p38 MAP kinase activation. 2013 Jun 2
38 22971992 EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin. 2013 Jan 1
39 23135610 (-)-Epigallocatechin 3-gallate inhibits invasion by inducing the expression of Raf kinase inhibitor protein in AsPC‑1 human pancreatic adenocarcinoma cells through the modulation of histone deacetylase activity. 2013 Jan 2
40 23839108 (-)-Epigallocatechin-3-gallate inhibits CC chemokine ligand 11 production in human gingival fibroblasts. 2013 1
41 21902673 (-)-Epigallocatechin gallate suppresses adipocyte differentiation through the MEK/ERK and PI3K/Akt pathways. 2012 Feb 4
42 20446926 (-)-Epigallocatechin-3-gallate down-regulates EGFR, MMP-2, MMP-9 and EMMPRIN and inhibits the invasion of MCF-7 tamoxifen-resistant cells. 2011 Apr 3
43 21725973 Epigallocatechin-3-gallate induces growth inhibition and apoptosis of human anaplastic thyroid carcinoma cells through suppression of EGFR/ERK pathway and cyclin B1/CDK1 complex. 2011 Dec 3
44 20043125 (-)-Epigallocatechin-3-gallate inhibits invasion and migration of salivary gland adenocarcinoma cells. 2010 Feb 1
45 20461739 Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts. 2010 Jul 2
46 20527725 Epigallocatechin-3-gallate (EGCG) downregulates gelatinase-B (MMP-9) by involvement of FAK/ERK/NFkappaB and AP-1 in the human breast cancer cell line MDA-MB-231. 2010 Jul 5
47 20623641 The polyphenol epigallocatechin-3-gallate affects lipid rafts to block activation of the c-Met receptor in prostate cancer cells. 2010 Aug 3
48 19135025 (-)-Epigallocatechin-3-gallate induces up-regulation of Th1 and Th2 cytokine genes in Jurkat T cells. 2009 Mar 1 6
49 19910679 Catechins inhibit CCL20 production in IL-17A-stimulated human gingival fibroblasts. 2009 1
50 18175946 Comparative examination of anti-proliferative activities of (-)-epigallocatechin gallate and (--)-epigallocatechin against HCT116 colorectal carcinoma cells. 2008 Jan 1