Threonine

mitogen-activated protein kinase 1 ; Homo sapiens







163 Article(s)
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51 21148411 Role of integrins in angiotensin II-induced proliferation of vascular smooth muscle cells. 2011 Mar 1
52 21344389 CCAAT-enhancer-binding protein beta activation of MMP-1 gene expression in SW1353 cells: independent roles of extracellular signal-regulated and p90/ribosomal S6 kinases. 2011 Dec 1
53 21772273 Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphoma. 2011 Jul 19 1
54 20178980 cAMP/CREB-mediated transcriptional regulation of ectonucleoside triphosphate diphosphohydrolase 1 (CD39) expression. 2010 May 7 1
55 20361728 Phosphorylation of the transcription factor Ets-1 by ERK2: rapid dissociation of ADP and phospho-Ets-1. 2010 May 4 2
56 20459645 Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells. 2010 May 7 1
57 20562913 Differential roles of ERK and Akt pathways in regulation of EGFR-mediated signaling and motility in prostate cancer cells. 2010 Sep 2 2
58 20882567 Sp1 phosphorylation is involved in myelin basic protein gene transcription. 2010 Nov 15 1
59 18686031 Thrombin-induced regulation of CD95(Fas) expression in the N9 microglial cell line: evidence for involvement of proteinase-activated receptor(1) and extracellular signal-regulated kinase 1/2. 2009 Mar 1
60 19007960 CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215. 2009 Jan 5 3
61 19361221 How mitogen-activated protein kinases recognize and phosphorylate their targets: A QM/MM study. 2009 May 6 1
62 19687304 TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling. 2009 Oct 2
63 19804359 EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells. 2009 Dec 1
64 18083711 The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125. 2008 Feb 15 1
65 18211802 ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA. 2008 Mar 28 1
66 18280112 DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5. 2008 May 1
67 18305109 A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest via p27 stabilization. 2008 Apr 25 1
68 18655826 Modulation of lysine acetylation-stimulated repressive activity by Erk2-mediated phosphorylation of RIP140 in adipocyte differentiation. 2008 Oct 3
69 18676833 Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. 2008 Aug 1 1
70 18682553 Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression. 2008 Aug 12 2
71 18720373 Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5. 2008 Dec 2
72 18762250 ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling. 2008 Nov 2
73 17215324 Src and focal adhesion kinase mediate mechanical strain-induced proliferation and ERK1/2 phosphorylation in human H441 pulmonary epithelial cells. 2007 May 1
74 17285175 The synthesis of phosphopeptides via the Bpoc-based approach. 2007 Feb 21 1
75 17404396 Involvement of ERKs, RSK2 and PKR in UVA-induced signal transduction toward phosphorylation of eIF2alpha (Ser(51)). 2007 Jul 1
76 17597065 Role of non-phosphorylated activation loop residues in determining ERK2 dephosphorylation, activity, and subcellular localization. 2007 Aug 24 3
77 17601773 Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. 2007 Jul 10 1
78 17623675 ERK2-mediated C-terminal serine phosphorylation of p300 is vital to the regulation of epidermal growth factor-induced keratin 16 gene expression. 2007 Sep 14 1
79 17693641 Phosphorylation blocks the activity of tubulin polymerization-promoting protein (TPPP): identification of sites targeted by different kinases. 2007 Oct 5 1
80 17717636 Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer. 2007 Dec 1
81 16197369 Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells. 2006 Feb 1 1
82 16336213 Characterization of the reversible phosphorylation and activation of ERK8. 2006 Feb 15 1
83 16453302 Interleukin-1 beta induction of matrix metalloproteinase-1 transcription in chondrocytes requires ERK-dependent activation of CCAAT enhancer-binding protein-beta. 2006 Jun 2
84 16785991 Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells. 2006 Dec 7 1
85 16848763 Phosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZ. 2006 Oct 15 2
86 17105191 Properties and regulation of a transiently assembled ERK2.Ets-1 signaling complex. 2006 Nov 21 4
87 15568999 MSK1 activity is controlled by multiple phosphorylation sites. 2005 Apr 15 1
88 15654082 Protein phosphatase 2A activity associated with Golgi membranes during the G2/M phase may regulate phosphorylation of ERK2. 2005 Mar 25 3
89 15665049 Alpha1-adrenoceptor-mediated phosphorylation of MYPT-1 and CPI-17 in the uterine artery: role of ERK/PKC. 2005 Jun 1
90 15709155 Various protein kinases regulate human sperm acrosome reaction and the associated phosphorylation of Tyr residues and of the Thr-Glu-Tyr motif. 2005 Mar 2
91 15865443 Hierarchical phosphorylation of the TNF-alpha receptor, TNF-R1, by p42Mapk/Erk at basic Pro-directed kinase sites. 2005 May 10 2
92 15899849 A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. 2005 Jun 1
93 15950189 Erk phosphorylates threonine 42 residue of ribosomal protein S3. 2005 Jul 22 2
94 16156666 Identification and characterization of ERK MAP kinase phosphorylation sites in Smad3. 2005 Sep 20 1
95 16314496 Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation. 2005 Dec 2
96 14593115 Fibroblast growth factor-2 represses platelet-derived growth factor receptor-alpha (PDGFR-alpha) transcription via ERK1/2-dependent Sp1 phosphorylation and an atypical cis-acting element in the proximal PDGFR-alpha promoter. 2004 Jan 23 2
97 14749719 p41-Arc subunit of human Arp2/3 complex is a p21-activated kinase-1-interacting substrate. 2004 Feb 1
98 15023352 A kinetic approach towards understanding substrate interactions and the catalytic mechanism of the serine/threonine protein kinase ERK2: identifying a potential regulatory role for divalent magnesium. 2004 Mar 11 2
99 15069082 ERK1/2 mediates insulin stimulation of Na(+),K(+)-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells. 2004 Jun 11 1
100 15073167 Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation. 2004 Jun 18 3