Superoxides

mitogen-activated protein kinase 1 ; Homo sapiens







45 Article(s)
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1 32942306 Cytoplasmic Radiation Induced Radio-Adaptive Response in Human Lung Fibroblast WI-38 Cells. 2020 Sep 16 1
2 33095057 Oxidative stress by Ca2+ overload is critical for phosphate-induced vascular calcification. 2020 Dec 1 1
3 31401382 Estradiol inhibits fMLP-induced neutrophil migration and superoxide production by upregulating MKP-2 and dephosphorylating ERK. 2019 Oct 1
4 31562365 NADPH oxidase is the major source of placental superoxide in early pregnancy: association with MAPK pathway activation. 2019 Sep 27 1
5 26840531 Dual-Functional Nanographene Oxide as Cancer-Targeted Drug-Delivery System to Selectively Induce Cancer-Cell Apoptosis. 2016 Apr 5 2
6 24140706 Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation. 2014 Feb 1
7 24742817 Respiratory sensitizer hexamethylene diisocyanate inhibits SOD 1 and induces ERK-dependent detoxifying and maturation pathways in dendritic-like cells. 2014 Jul 1
8 25069039 Critical roles for nitric oxide and ERK in the completion of prosurvival autophagy in 4OHTAM-treated estrogen receptor-positive breast cancer cells. 2014 Oct 28 1
9 23613809 Superoxide mediates direct current electric field-induced directional migration of glioma cells through the activation of AKT and ERK. 2013 1
10 24358134 Ras and Rac1, frequently mutated in melanomas, are activated by superoxide anion, modulate Dnmt1 level and are causally related to melanocyte malignant transformation. 2013 1
11 22082048 NADPH oxidase is involved in H2O2-induced differentiation of human promyelocytic leukaemia HL-60 cells. 2012 Apr 1 1
12 22213462 Effects of indoxyl sulfate on adherens junctions of endothelial cells and the underlying signaling mechanism. 2012 Mar 1
13 22406317 Superoxide plays critical roles in electrotaxis of fibrosarcoma cells via activation of ERK and reorganization of the cytoskeleton. 2012 May 1 2
14 22469513 Mitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitination. 2012 Jun 15 1
15 22634165 Splitomicin inhibits fMLP-induced superoxide anion production in human neutrophils by activate cAMP/PKA signaling inhibition of ERK pathway. 2012 Aug 5 1
16 22823229 Modulation of interferon-γ-induced glial cell activation by transforming growth factor β1: a role for STAT1 and MAPK pathways. 2012 Oct 1
17 20397192 Carbonyl compounds methylglyoxal and glyoxal affect interleukin-8 secretion in intestinal cells by superoxide anion generation and activation of MAPK p38. 2010 Oct 1
18 19268487 Superoxide radicals increase transforming growth factor-beta1 and collagen release from human lung fibroblasts via cellular influx through chloride channels. 2009 May 15 1
19 18440651 Interferon-gamma enhances human eosinophil effector functions induced by granulocyte-macrophage colony-stimulating factor or interleukin-5. 2008 Jun 15 1
20 16543474 FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways. 2006 Jul 15 1
21 16829532 Superoxide fluxes limit nitric oxide-induced signaling. 2006 Sep 8 1
22 16919916 Participation of superoxide in neutrophil activation and cytokine production. 2006 Aug 1
23 17384286 Superoxide anions are involved in doxorubicin-induced ERK activation in hepatocyte cultures. 2006 Dec 1
24 16115878 Interleukin-8-induced priming of neutrophil oxidative burst requires sequential recruitment of NADPH oxidase components into lipid rafts. 2005 Nov 4 1
25 14681237 Ras induction of superoxide activates ERK-dependent angiogenic transcription factor HIF-1alpha and VEGF-A expression in shock wave-stimulated osteoblasts. 2004 Mar 12 3
26 14767997 CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling. 2004 Feb 1
27 15111505 Insulin generates free radicals by an NAD(P)H, phosphatidylinositol 3'-kinase-dependent mechanism in human skin fibroblasts ex vivo. 2004 May 1
28 15155776 CP-64131, an aminobenzazepine with cytokine-like properties, stimulates human neutrophil functions through the p38-MAPK pathway. 2004 Aug 2
29 12731668 Serine protease inhibitors inhibit superoxide release and adherence in human neutrophils stimulated by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha. 2003 Apr 3
30 12793995 Differential role of PTK and ERK MAPK in superoxide impairment of K(ATP) and K(Ca) channel cerebrovasodilation. 2003 Jul 8
31 12920210 Differential signaling of formyl peptide receptor-like 1 by Trp-Lys-Tyr-Met-Val-Met-CONH2 or lipoxin A4 in human neutrophils. 2003 Sep 1
32 14499342 MAPK-activated protein kinase-2 participates in p38 MAPK-dependent and ERK-dependent functions in human neutrophils. 2003 Nov 2
33 11818515 The extracellular signal-regulated kinase (ERK) pathway is involved in human sperm function and modulated by the superoxide anion. 2002 Feb 5
34 11997240 Hypertonicity increases cAMP in PMN and blocks oxidative burst by PKA-dependent and -independent mechanisms. 2002 Jun 2
35 12083801 Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929. 2002 Jul 15 2
36 11134248 Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies. 2001 Jan 2
37 11145700 Cleavage of mitogen-activated protein kinases in human neutrophils undergoing apoptosis: role in decreased responsiveness to inflammatory cytokines. 2001 Jan 15 3
38 11282164 Intracellular pathways involved in TNF-alpha and superoxide anion release by Abeta(1-42)-stimulated primary human macrophages. 2001 Apr 2 1
39 11509539 Mechanism of inhibition of matrix metalloproteinase-9 induction by NO in vascular smooth muscle cells. 2001 Sep 2
40 11709424 Role of reactive oxygen species in IL-1 beta-stimulated sustained ERK activation and MMP-9 induction. 2001 Dec 1
41 9864179 Cytokine-specific activation of distinct mitogen-activated protein kinase subtype cascades in human neutrophils stimulated by granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, and tumor necrosis factor-alpha. 1999 Jan 1 4
42 10378896 Signal transduction pathways in normal human monocytes stimulated by cytokines and mediators: comparative study with normal human neutrophils or transformed cells and the putative roles in functionality and cell biology. 1999 Jun 2
43 10522849 Extracellular signal-related kinase 1/2 and p38 mitogen-activated protein kinase pathways serve opposite roles in neutrophil cytotoxicity. 1999 Oct 3
44 10667354 Involvement of protein kinase C, p38 MAP kinase and ERK in arachidonic acid-stimulated superoxide production in human neutrophils. 1999 1
45 9766635 Activation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-alpha and GM-CSF. 1998 Oct 1