Hydrogen Peroxide

mitogen-activated protein kinase 1 ; Homo sapiens







222 Article(s)
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51 27637085 Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A. 2016 Oct 18 1
52 27659916 ERK-mediated phosphorylation of BIS regulates nuclear translocation of HSF1 under oxidative stress. 2016 Sep 23 2
53 27754784 5α-Androstane-3α,17β-Diol Inhibits Neurotoxicity in SH-SY5Y Human Neuroblastoma Cells and Mouse Primary Cortical Neurons. 2016 Dec 3
54 28598074 [Sodium Ferulate Attenuates Oxidative Stressvia Suppressing NALP3 Inflammasome and ERK Signal Pathway]. 2016 Sep 6
55 25683165 Sirtuin 6 promotes transforming growth factor-β1/H2O2/HOCl-mediated enhancement of hepatocellular carcinoma cell tumorigenicity by suppressing cellular senescence. 2015 May 1
56 25825208 Superoxide dismutase promotes the epithelial-mesenchymal transition of pancreatic cancer cells via activation of the H2O2/ERK/NF-κB axis. 2015 2
57 25831202 Caffeic acid improves cell viability and protects against DNA damage: involvement of reactive oxygen species and extracellular signal-regulated kinase. 2015 Jun 1
58 25921766 Protective effect of geranylgeranylacetone against hydrogen peroxide-induced oxidative stress in human neuroblastoma cells. 2015 Jun 15 1
59 26047336 Urotensin II Protects Cardiomyocytes from Apoptosis Induced by Oxidative Stress through the CSE/H2S Pathway. 2015 Jun 3 3
60 26064424 The Neuroprotective Effects of Ratanasampil on Oxidative Stress-Mediated Neuronal Damage in Human Neuronal SH-SY5Y Cells. 2015 1
61 26234813 Csk-Induced Phosphorylation of Src at Tyrosine 530 is Essential for H2O2-Mediated Suppression of ERK1/2 in Human Umbilical Vein Endothelial Cells. 2015 Aug 3 3
62 26439801 Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer. 2015 Oct 13 9
63 26542288 Betulinic acid downregulates expression of oxidative stress-induced lipoprotein lipase via the PKC/ERK/c-Fos pathway in RAW264.7 macrophages. 2015 Dec 1
64 26710786 [Heat-shock protein HSP70 protects neuroblastoma cells SK-N-SH from the neurotoxic effects hydrogen peroxide and the β-amyloid peptide]. 2015 Nov-Dec 1
65 23815460 Involvement of SDF-1 and monocyte chemoattractant protein-1 in hydrogen peroxide-induced extracellular matrix degradation in human dental pulp cells. 2014 Mar 1
66 24140706 Arctigenin, a dietary phytoestrogen, induces apoptosis of estrogen receptor-negative breast cancer cells through the ROS/p38 MAPK pathway and epigenetic regulation. 2014 Feb 1
67 24440775 Neuroprotective effects of amlodipine besylate and benidipine hydrochloride on oxidative stress-injured neural stem cells. 2014 Mar 10 1
68 24577881 Oxidative stress, T cell DNA methylation, and lupus. 2014 Jun 1
69 24586933 Role of the ERK pathway for oxidant-induced parthanatos in human lymphocytes. 2014 1
70 24632723 SHP-2 binds to caveolin-1 and regulates Src activity via competitive inhibition of CSK in response to H2O2 in astrocytes. 2014 2
71 24871786 Transient receptor potential melastatin 7 (TRPM7) contributes to H2O2-induced cardiac fibrosis via mediating Ca(2+) influx and extracellular signal-regulated kinase 1/2 (ERK1/2) activation in cardiac fibroblasts. 2014 2
72 24912447 Activated δ‑opioid receptors inhibit hydrogen peroxide‑induced apoptosis in liver cancer cells through the PKC/ERK signaling pathway. 2014 Aug 1
73 25069610 Astragalin inhibits airway eotaxin-1 induction and epithelial apoptosis through modulating oxidative stress-responsive MAPK signaling. 2014 Jul 29 1
74 25078118 The role of p38 signaling and poly(ADP-ribosyl)ation-induced metabolic collapse in the osteogenic differentiation-coupled cell death pathway. 2014 Nov 6
75 25128742 Novel role of silent information regulator 1 in acute endothelial cell oxidative stress injury. 2014 Nov 1
76 23247634 Vitamin D protects human endothelial cells from H₂O₂ oxidant injury through the Mek/Erk-Sirt1 axis activation. 2013 Apr 1
77 23261939 Increase of oxidative stress by a novel PINK1 mutation, P209A. 2013 May 1
78 23478801 Neuroglobin, a novel intracellular hexa-coordinated globin, functions as a tumor suppressor in hepatocellular carcinoma via Raf/MAPK/Erk. 2013 May 1
79 23569422 Propofol-induced protection of SH-SY5Y cells against hydrogen peroxide is associated with the HO-1 via the ERK pathway. 2013 1
80 23624332 Integrin-linked kinase mediates the hydrogen peroxide-dependent transforming growth factor-β1 up-regulation. 2013 Aug 2
81 23805040 Oxidative stress response signaling pathways in trabecular meshwork cells and their effects on cell viability. 2013 4
82 24008236 Endothelial nitric oxide synthase phosphorylation at Threonine 495 and mitochondrial reactive oxygen species formation in response to a high H₂O₂ concentration. 2013 1
83 24058693 Contribution of S6K1/MAPK signaling pathways in the response to oxidative stress: activation of RSK and MSK by hydrogen peroxide. 2013 3
84 21946416 Pigment epithelium-derived factor (PEDF) protects cortical neurons in vitro from oxidant injury by activation of extracellular signal-regulated kinase (ERK) 1/2 and induction of Bcl-2. 2012 Jan 1
85 22082048 NADPH oxidase is involved in H2O2-induced differentiation of human promyelocytic leukaemia HL-60 cells. 2012 Apr 1 4
86 22246135 Flavonoid baicalein modulates H2O2-induced mitogen-activated protein kinases activation and cell death in SK-N-MC cells. 2012 May 1
87 22342995 p38(MAPK) and ERK1/2 dictate cell death/survival response to different pro-oxidant stimuli via p53 and Nrf2 in neuroblastoma cells SH-SY5Y. 2012 May 15 1
88 22507555 Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway. 2012 Oct 2
89 22683469 Post-transcriptional regulation of placenta growth factor mRNA by hydrogen peroxide. 2012 Sep 1
90 23243457 Inhibition of Connexin 26/43 and Extracellular-Regulated Kinase Protein Plays a Critical Role in Melatonin Facilitated Gap Junctional Intercellular Communication in Hydrogen Peroxide-Treated HaCaT Keratinocyte Cells. 2012 2
91 20961289 Contrasting effects of ERK on tight junction integrity in differentiated and under-differentiated Caco-2 cell monolayers. 2011 Jan 1 2
92 21241762 Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cells. 2011 Mar 3
93 21315693 Preventing H₂O₂-induced apoptosis in cerebellar granule neurons by regulating the VEGFR-2/Akt signaling pathway using a novel dimeric antiacetylcholinesterase bis(12)-hupyridone. 2011 Jun 7 3
94 21344509 Oncogenic H-Ras, FK228, and exogenous H2O2 cooperatively activated the ERK pathway in selective induction of human urinary bladder cancer J82 cell death. 2011 Mar 2
95 21397862 Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors. 2011 Mar 8 1
96 21467197 Ghrelin inhibits hydrogen peroxide-induced apoptotic cell death of oligodendrocytes via ERK and p38MAPK signaling. 2011 Jun 5
97 21497337 Melatonin protects human spermatozoa from apoptosis via melatonin receptor- and extracellular signal-regulated kinase-mediated pathways. 2011 Jun 1
98 21557328 Inhibition of ERK oscillations by ionizing radiation and reactive oxygen species. 2011 Jun 1
99 21566137 Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers. 2011 Jul 8 1
100 21630016 Defective nuclear translocation of stress-activated signaling in senescent diploid human fibroblasts: a possible explanation for aging-associated apoptosis resistance. 2011 Aug 4