Reactive Oxygen Species

mitogen-activated protein kinase 1 ; Homo sapiens







336 Article(s)
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151 24472723 Silibinin induces cell death through reactive oxygen species-dependent downregulation of notch-1/ERK/Akt signaling in human breast cancer cells. 2014 May 1
152 24491913 Inhibition of Notch signaling leads to increased intracellular ROS by up-regulating Nox4 expression in primary HUVECs. 2014 Feb 1
153 24586933 Role of the ERK pathway for oxidant-induced parthanatos in human lymphocytes. 2014 4
154 24587680 Chloride intracellular channel 1 regulates colon cancer cell migration and invasion through ROS/ERK pathway. 2014 Feb 28 3
155 24623131 Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function. 2014 Apr 15 1
156 24720336 Hyperglycemia regulates TXNIP/TRX/ROS axis via p38 MAPK and ERK pathways in pancreatic cancer. 2014 2
157 24763048 Enhancement of auranofin-induced lung cancer cell apoptosis by selenocystine, a natural inhibitor of TrxR1 in vitro and in vivo. 2014 Apr 24 4
158 24797310 Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling. 2014 May 15 1
159 24824657 Reactive oxygen species induce the association of SHP-1 with c-Src and the oxidation of both to enhance osteoclast survival. 2014 Jul 1 1
160 24874889 Taiwan cobra phospholipase A2 suppresses ERK-mediated ADAM17 maturation, thus reducing secreted TNF-α production in human leukemia U937 cells. 2014 Aug 4
161 24952354 Sulforaphane induces autophagy through ERK activation in neuronal cells. 2014 Aug 25 2
162 24963595 Verrucarin A induces apoptosis through ROS-mediated EGFR/MAPK/Akt signaling pathways in MDA-MB-231 breast cancer cells. 2014 Nov 1
163 25027398 Verrucarin A alters cell-cycle regulatory proteins and induces apoptosis through reactive oxygen species-dependent p38MAPK activation in the human breast cancer cell line MCF-7. 2014 Oct 1
164 25079440 TCF2 attenuates FFA-induced damage in islet β-cells by regulating production of insulin and ROS. 2014 Jul 30 2
165 25110320 Survival signaling elicited by 27-hydroxycholesterol through the combined modulation of cellular redox state and ERK/Akt phosphorylation. 2014 Dec 1
166 22688575 Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells. 2013 May 1
167 22961925 Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils. 2013 Mar 12
168 23186333 Prx I suppresses K-ras-driven lung tumorigenesis by opposing redox-sensitive ERK/cyclin D1 pathway. 2013 Aug 10 5
169 23239052 Hyperglycemia accelerates ATP-binding cassette transporter A1 degradation via an ERK-dependent pathway in macrophages. 2013 Jun 4
170 23337889 Prolonged activation of ERK contributes to the photorejuvenation effect in photodynamic therapy in human dermal fibroblasts. 2013 Sep 1
171 23370007 APE1/Ref-1 prevents oxidative inactivation of ERK for G1-to-S progression following lead acetate exposure. 2013 Mar 8 1
172 23417518 Growth inhibition and apoptosis of neuroblastoma cells through ROS-independent MEK/ERK activation by sulforaphane. 2013 Jul 1
173 23433299 Grape seed extract triggers apoptosis in Caco-2 human colon cancer cells through reactive oxygen species and calcium increase: extracellular signal-regulated kinase involvement. 2013 Sep 14 2
174 23436183 Signal inhibitory receptor on leukocytes-1 (SIRL-1) negatively regulates the oxidative burst in human phagocytes. 2013 May 2
175 23443487 A crucial role for reactive oxygen species in macrophage colony-stimulating factor-induced RANK expression in osteoclastic differentiation. 2013 Apr 1
176 23467622 Role of oxidative stress, endoplasmic reticulum stress and ERK activation in triptolide-induced apoptosis. 2013 May 3
177 23481041 Low electric fields induce ligand-independent activation of EGF receptor and ERK via electrochemical elevation of H(+) and ROS concentrations. 2013 Jun 1
178 23490067 Arachidonic acid enhances TPA-induced differentiation in human leukemia HL-60 cells via reactive oxygen species-dependent ERK activation. 2013 Apr 2
179 23500541 Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy. 2013 May 15 1
180 23579275 Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2. 2013 Apr 11 1
181 23614740 Carnosic acid, a phenolic diterpene from rosemary, prevents UV-induced expression of matrix metalloproteinases in human skin fibroblasts and keratinocytes. 2013 May 4
182 23633517 RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species. 2013 Sep 3
183 23684072 Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: role for reactive oxygen species-enhanced MEK/ERK activation. 2013 Aug 4
184 23684917 Quercetin-3-O-(2″-galloyl)-α-l-rhamnopyranoside inhibits TNF-α-activated NF-κB-induced inflammatory mediator production by suppressing ERK activation. 2013 Aug 1
185 23708648 Khat (Catha edulis) generates reactive oxygen species and promotes hepatic cell apoptosis via MAPK activation. 2013 Aug 1
186 23729024 Effectiveness of miltefosine treatment in targeting anti-leishmanial HO-1/Nrf-2-mediated oxidative responses in visceral leishmaniasis patients. 2013 Sep 1
187 23743194 Synergistic induction of cancer cell death and reduction of clonogenic resistance by cisplatin and FK228. 2013 Jun 28 1
188 23760395 Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling. 2013 May 3
189 23837948 Selenocystine potentiates cancer cell apoptosis induced by 5-fluorouracil by triggering reactive oxygen species-mediated DNA damage and inactivation of the ERK pathway. 2013 Dec 2
190 24008236 Endothelial nitric oxide synthase phosphorylation at Threonine 495 and mitochondrial reactive oxygen species formation in response to a high H₂O₂ concentration. 2013 1
191 24040019 Synergistic apoptosis of CML cells by buthionine sulfoximine and hydroxychavicol correlates with activation of AIF and GSH-ROS-JNK-ERK-iNOS pathway. 2013 1
192 24094550 Regulation of ROS-independent ERK signaling rescues replicative cellular senescence in ex vivo expanded human c-kit-positive cardiac progenitor cells. 2013 Oct 25 3
193 24097820 Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance. 2013 Oct 15 2
194 24367671 Peripheral neutrophil functions and cell signalling in Crohn`s disease. 2013 1
195 24383372 TGF-beta1-Induced MAPK activation promotes collagen synthesis, nodule formation, redox stress and cellular senescence in porcine aortic valve interstitial cells. 2013 Sep 1
196 21870211 Imaging the impact of Nox4 in cycling hypoxia-mediated U87 glioblastoma invasion and infiltration. 2012 Aug 2
197 21899994 Danshen-Gegen decoction protects against hypoxia/reoxygenation-induced apoptosis by inhibiting mitochondrial permeability transition via the redox-sensitive ERK/Nrf2 and PKCε/mKATP pathways in H9c2 cardiomyocytes. 2012 Jan 15 1
198 21964032 Extracellular cysteine (Cys)/cystine (CySS) redox regulates metabotropic glutamate receptor 5 activity. 2012 Mar 2
199 21984483 Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells. 2012 Jan 1
200 22045026 Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. 2012 Jan 5