Reactive Oxygen Species

mitogen-activated protein kinase 1 ; Homo sapiens







336 Article(s)
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101 28524116 Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells. 2017 May 18 4
102 28545088 Transcriptional activation of HIF-1 by a ROS-ERK axis underlies the resistance to photodynamic therapy. 2017 1
103 28548942 The N-terminal tail coordinates with carbohydrate recognition domain to mediate galectin-3 induced apoptosis in T cells. 2017 Jul 25 2
104 28572156 G-protein-coupled receptor kinase-2 is a critical regulator of TNFα signaling in colon epithelial cells. 2017 Jun 27 3
105 28595656 ROS production induced by BRAF inhibitor treatment rewires metabolic processes affecting cell growth of melanoma cells. 2017 Jun 8 1
106 28893319 Sophoridine induces apoptosis and S phase arrest via ROS-dependent JNK and ERK activation in human pancreatic cancer cells. 2017 Sep 11 1
107 28944886 Sulforaphane induces p53‑deficient SW480 cell apoptosis via the ROS‑MAPK signaling pathway. 2017 Nov 5
108 25876056 PM2.5-induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF-κB-dependent pathway. 2016 Jan 1
109 26320741 The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytes. 2016 Nov 2
110 26711691 Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis. 2016 May 15 1
111 26804739 Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition. 2016 Jan 25 1
112 26808296 Helicobacter pylori induces Snail expression through ROS-mediated activation of Erk and inactivation of GSK-3β in human gastric cancer cells. 2016 Dec 4
113 26810068 GRIM-19 inhibition induced autophagy through activation of ERK and HIF-1α not STAT3 in Hela cells. 2016 Jul 3
114 26840563 Oxidation of heat shock protein 60 and protein disulfide isomerase activates ERK and migration of human hepatocellular carcinoma HepG2. 2016 Mar 8 3
115 26889254 Protocatechuic aldehyde inhibits TNF-α-induced fibronectin expression in human umbilical vein endothelial cells via a c-Jun N-terminal kinase dependent pathway. 2016 Jan 2
116 27016209 Giganteaside D induces ROS-mediated apoptosis in human hepatocellular carcinoma cells through the MAPK pathway. 2016 Aug 2
117 27035858 Inhibition of autophagic flux by ROS promotes apoptosis during DTT-induced ER/oxidative stress in HeLa cells. 2016 Jun 3
118 27052425 Nox4 has a crucial role in uric acid‑induced oxidative stress and apoptosis in renal tubular cells. 2016 May 2
119 27058530 Power Frequency Magnetic Fields Affect the p38 MAPK-Mediated Regulation of NB69 Cell Proliferation Implication of Free Radicals. 2016 Apr 6 1
120 27248323 Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2. 2016 Jul 12 2
121 27278736 Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways. 2016 Aug 3
122 27313009 Urban particulate matter down-regulates filaggrin via COX2 expression/PGE2 production leading to skin barrier dysfunction. 2016 Jun 17 2
123 27318969 16-hydroxy-cleroda-3,13-dien-16,15-olide induced glioma cell autophagy via ROS generation and activation of p38 MAPK and ERK-1/2. 2016 Jul 2
124 27423393 PINK1 alleviates palmitate induced insulin resistance in HepG2 cells by suppressing ROS mediated MAPK pathways. 2016 Sep 9 1
125 27572503 Curcumin inhibits H2O2-induced invasion and migration of human pancreatic cancer via suppression of the ERK/NF-κB pathway. 2016 Oct 1
126 27577048 The oncometabolite R-2-hydroxyglutarate activates NF-κB-dependent tumor-promoting stromal niche for acute myeloid leukemia cells. 2016 Aug 31 1
127 27941930 ERK-mediated NF-κB activation through ASIC1 in response to acidosis. 2016 Dec 12 3
128 28111550 N-n-butyl Haloperidol Iodide Protects against Hypoxia/Reoxygenation Injury in Cardiac Microvascular Endothelial Cells by Regulating the ROS/MAPK/Egr-1 Pathway. 2016 3
129 25138434 Quercetin induces mitochondrial-derived apoptosis via reactive oxygen species-mediated ERK activation in HL-60 leukemia cells and xenograft. 2015 Jul 1
130 25249341 Mitochondrial KATP Channels Control Glioma Radioresistance by Regulating ROS-Induced ERK Activation. 2015 Aug 3
131 25471815 α-Tocopherol protects renal cells from nicotine- or oleic acid-provoked oxidative stress via inducing heme oxygenase-1. 2015 Mar 1
132 25540919 Resveratrol prevents high glucose-induced epithelial-mesenchymal transition in renal tubular epithelial cells by inhibiting NADPH oxidase/ROS/ERK pathway. 2015 Feb 15 1
133 25546605 Regulation of hypoxia-inducible factor-1a by reactive oxygen species: new developments in an old debate. 2015 May 1
134 25606812 Fucoidan protects ARPE-19 cells from oxidative stress via normalization of reactive oxygen species generation through the Ca²⁺-dependent ERK signaling pathway. 2015 May 1
135 25714249 Chlorogenic acid enhances the effects of 5-fluorouracil in human hepatocellular carcinoma cells through the inhibition of extracellular signal-regulated kinases. 2015 Jun 2
136 25891473 Anti-proliferative and pro-apoptotic activities of Alpinia oxyphylla on HepG2 cells through ROS-mediated signaling pathway. 2015 Jul 1 1
137 25903517 Phosphoinositide and Erk signaling pathways mediate activity-driven rodent olfactory sensory neuronal survival and stress mitigation. 2015 Aug 1
138 25919890 Undifferentiated Neuroblastoma Cells Are More Sensitive to Photogenerated Oxidative Stress Than Differentiated Cells. 2015 Sep 2
139 25965299 Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells. 2015 May 12 1
140 25982794 Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway. 2015 Jun 3
141 26086160 Reactive oxygen species mediate nitric oxide production through ERK/JNK MAPK signaling in HAPI microglia after PFOS exposure. 2015 Oct 15 2
142 26164795 III-10, a newly synthesized flavonoid, induces cell apoptosis with the involvement of reactive oxygen species-mitochondria pathway in human hepatocellular carcinoma cells. 2015 Oct 5 2
143 26222138 NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages. 2015 1
144 26288183 Inhibition of Autophagy Potentiated the Antitumor Effect of Nedaplatin in Cisplatin-Resistant Nasopharyngeal Carcinoma Cells. 2015 3
145 26322231 Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation. 2015 2
146 26472194 ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine. 2015 Dec 2
147 26500049 SL4, a chalcone-based compound, induces apoptosis in human cancer cells by activation of the ROS/MAPK signalling pathway. 2015 Dec 2
148 24361401 Simulated microgravity increases heavy ion radiation-induced apoptosis in human B lymphoblasts. 2014 Mar 3 2
149 24424405 FFAs-ROS-ERK/P38 pathway plays a key role in adipocyte lipotoxicity on osteoblasts in co-culture. 2014 Jun 6
150 24448387 9-Hydroxypheophorbide α-mediated photodynamic therapy induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in Hep-2 cells via ROS-mediated suppression of the ERK pathway. 2014 Mar 2