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mitogen-activated protein kinase 1 ; Homo sapiens







96 Article(s)
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51 26089952 Polypeptide Fraction from Arca subcrenata Induces Apoptosis and G2/M Phase Arrest in HeLa Cells via ROS-Mediated MAPKs Pathways. 2015 1
52 26107995 Functionalized Multiwalled Carbon Nanotubes as Carriers of Ruthenium Complexes to Antagonize Cancer Multidrug Resistance and Radioresistance. 2015 Jul 15 1
53 26212545 Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells. 2015 Sep 1 2
54 26465677 A Novel Platinum-Maurocalcine Conjugate Induces Apoptosis of Human Glioblastoma Cells by Acting through the ROS-ERK/AKT-p53 Pathway. 2015 Dec 7 1
55 26642060 bFGF-Regulating MAPKs Are Involved in High Glucose-Mediated ROS Production and Delay of Vascular Endothelial Cell Migration. 2015 3
56 24122234 Amsacrine suppresses matrix metalloproteinase-2 (MMP-2)/MMP-9 expression in human leukemia cells. 2014 May 2
57 24555485 Synergistic induction of apoptosis by methylseleninic acid and cisplatin, the role of ROS-ERK/AKT-p53 pathway. 2014 Apr 7 1
58 24586814 The pentachlorophenol metabolite tetrachlorohydroquinone induces massive ROS and prolonged p-ERK expression in splenocytes, leading to inhibition of apoptosis and necrotic cell death. 2014 2
59 24930757 Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways. 2014 Sep 2
60 25044446 Oxidized HDL induces cytotoxic effects: implications for atherogenic mechanism. 2014 Nov 1
61 25065405 Mitochondrial dynamics regulate melanogenesis through proteasomal degradation of MITF via ROS-ERK activation. 2014 Nov 4
62 25135223 Strategy to enhance the anticancer efficacy of X-ray radiotherapy in melanoma cells by platinum complexes, the role of ROS-mediated signaling pathways. 2014 Nov 1 1
63 23220614 MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells. 2013 Mar 1
64 23353183 Crosstalk from survival to necrotic death coexists in DU-145 cells by curcumin treatment. 2013 May 1
65 23416140 JNK and p38 MAPK regulate oxidative stress and the inflammatory response in chlorpyrifos-induced apoptosis. 2013 Apr 26 1
66 23696052 Biomarkers of sensitivity to potent and selective antitumor 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F203) in ovarian cancer. 2013 Oct 1
67 23707387 Cross talk between p38MAPK and ERK is mediated through MAPK-mediated protein phosphatase 2A catalytic subunit α and MAPK phosphatase-1 expression in human leukemia U937 cells. 2013 Sep 1
68 23733672 Surfactin-induced apoptosis through ROS-ERS-Ca2+-ERK pathways in HepG2 cells. 2013 2
69 23758151 Induction of miR-21-PDCD4 signaling by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS-mediated MAPK pathways. 2013 1
70 23876460 Cadmium induces N-cadherin cleavage via ERK-mediated γ-secretase activation in C6 astroglia cells. 2013 Oct 24 1
71 24001789 ZnO nanoparticles induce TNF-α expression via ROS-ERK-Egr-1 pathway in human keratinocytes. 2013 Dec 2
72 21882190 High glucose-induced repression of RAR/RXR in cardiomyocytes is mediated through oxidative stress/JNK signaling. 2012 Jun 1
73 22288910 Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell line. 2012 Mar 19 1
74 22544998 Oxidative stress and microglial cells in Parkinson's disease. 2012 1
75 21453688 Vitamin K3-2,3-epoxide induction of apoptosis with activation of ROS-dependent ERK and JNK protein phosphorylation in human glioma cells. 2011 Aug 15 1
76 21620957 ROS-activated p38 MAPK/ERK-Akt cascade plays a central role in palmitic acid-stimulated hepatocyte proliferation. 2011 Jul 15 4
77 21998736 β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells. 2011 4
78 19700217 Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells. 2010 Jun 1
79 19939451 Rac/ROS-related protein kinase C and phosphatidylinositol-3-kinase signaling are involved in a negative regulating cascade in B cell activation by antibody-mediated cross-linking of MHC class II molecules. 2010 Jan 1
80 20360613 Role of endothelin-1 receptor blockers on hemodynamic parameters and oxidative stress. 2010 Jan-Feb 1
81 20368806 Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation. 2010 Apr 2 2
82 20402656 Cytotoxicity of a vanadyl(IV) complex with a multidentate oxygen donor in osteoblast cell lines in culture. 2010 Jan 1
83 20430109 Japanese encephalitis virus down-regulates thioredoxin and induces ROS-mediated ASK1-ERK/p38 MAPK activation in human promonocyte cells. 2010 Aug 2
84 20432471 Caffeine induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-fos pathway and activation of p38 MAPK/c-jun pathway. 2010 Sep 3
85 19009558 Upregulation of Fas and FasL in Taiwan cobra phospholipase A2-treated human neuroblastoma SK-N-SH cells through ROS- and Ca2+-mediated p38 MAPK activation. 2009 Jan 1 3
86 19249354 Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption. 2009 Jun 1
87 19720122 Arachidonic acid induces Fas and FasL upregulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-Fos pathway and activation of p38 MAPK/ATF-2 pathway. 2009 Dec 15 2
88 20150959 Regulation of chemokine production via oxidative pathway in HeLa cells. 2009 1
89 18064629 All-trans retinoic acid attenuates ultraviolet radiation-induced down-regulation of aquaporin-3 and water permeability in human keratinocytes. 2008 May 1
90 18723357 Development and biological evaluation of C(60) fulleropyrrolidine-thalidomide dyad as a new anti-inflammation agent. 2008 Sep 15 1
91 16632126 Notoginsenoside R1 inhibits TNF-alpha-induced fibronectin production in smooth muscle cells via the ROS/ERK pathway. 2006 May 1 3
92 16904205 Increased stability of P21(WAF1/CIP1) mRNA is required for ROS/ERK-dependent pancreatic adenocarcinoma cell growth inhibition by pyrrolidine dithiocarbamate. 2006 Sep 1
93 15880691 Inhibition of extracellular signal regulated kinase (ERK) leads to apoptosis inducing factor (AIF) mediated apoptosis in epithelial breast cancer cells: the lack of effect of ERK in p53 mediated copper induced apoptosis. 2005 Aug 15 1
94 15226155 EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1/2 are required for ROS-induced renal cell death. 2004 Nov 1
95 12151316 Proteasome inhibitors stimulate interleukin-8 expression via Ras and apoptosis signal-regulating kinase-dependent extracellular signal-related kinase and c-Jun N-terminal kinase activation. 2002 Aug 1
96 9546582 Identification and activation of mitogen-activated protein (MAP) kinase in normal human osteoblastic and bone marrow stromal cells: attenuation of MAP kinase activation by cAMP, parathyroid hormone and forskolin. 1998 Jan 2