quinone

heat shock protein 90 alpha family class A member 1 ; Homo sapiens







20 Article(s)
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1 32799638 Identification of the naphthoquinone derivative inhibitors binding site in heat shock protein 90: an induced-fit docking, molecular dynamics and 3D-QSAR study. 2021 Oct 1
2 32868290 Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF2. 2020 Oct 26 1
3 25572106 New, non-quinone fluorogeldanamycin derivatives strongly inhibit Hsp90. 2015 Jan 19 1
4 25668752 Reaction design, discovery, and development as a foundation to function-oriented synthesis. 2015 Mar 17 1
5 26674599 HSP90 Inhibitor Geldanamycin as a Radiation Response Modificator in Human Blood Cells. 2015 Jan-Mar 1
6 24682466 19-substituted benzoquinone ansamycin heat shock protein-90 inhibitors: biological activity and decreased off-target toxicity. 2014 Jun 1
7 25117641 Anti-tumor activity of WK88-1, a novel geldanamycin derivative, in gefitinib-resistant non-small cell lung cancers with Met amplification. 2014 Oct 1
8 23710334 DTNQ-Pro, a Mimetic Dipeptide, Sensitizes Human Colon Cancer Cells to 5-Fluorouracil Treatment. 2013 1
9 23167798 Biological evaluation of 3-acyl-2-arylamino-1,4-naphthoquinones as inhibitors of Hsp90 chaperoning function. 2012 2
10 21156818 Role for NAD(P)H:quinone oxidoreductase 1 and manganese-dependent superoxide dismutase in 17-(allylamino)-17-demethoxygeldanamycin-induced heat shock protein 90 inhibition in pancreatic cancer cells. 2011 Mar 1
11 19908836 Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone. 2010 Jan 14 1
12 19308924 Rational biosynthetic engineering for optimization of geldanamycin analogues. 2009 May 4 1
13 19441108 Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma. 2009 Jul 1
14 19952119 The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo. 2009 Dec 1
15 18393300 Stability of the Hsp90 inhibitor 17AAG hydroquinone and prevention of metal-catalyzed oxidation. 2008 Dec 1
16 19568319 Synthesis of a versatile metacyclophane macrolactam. 2008 Jan 1 1
17 17662999 Mechanistic studies on Hsp90 inhibition by ansamycin derivatives. 2007 Sep 14 1
18 17163756 Tumor selectivity of Hsp90 inhibitors: the explanation remains elusive. 2006 Jun 20 1
19 15867239 Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers. 2005 May 1 2
20 15202892 Biotinylated geldanamycin. 2004 Jun 25 1