Steroids

heat shock protein 90 alpha family class A member 1 ; Homo sapiens







66 Article(s)
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1 33846988 Targeting the HSP90-CDC37-kinase chaperone cycle: A promising therapeutic strategy for cancer. 2022 Jan 2
2 34432285 MicroRNAs and Heat Shock Proteins in Breast Cancer Biology. 2022 1
3 32776605 Heat shock protein HSP90 immunoexpression in equine endometrium during oestrus, dioestrus and anoestrus. 2021 Jan 2
4 33245994 Assay design and development strategies for finding Hsp90 inhibitors and their role in human diseases. 2021 May 2
5 33390129 Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro Degenerative Diseases. 2021 1
6 34420854 Corticosteroid receptors as a model for the Hsp90•immunophilin-based transport machinery. 2021 Oct 2
7 32612187 Glucocorticoid receptor complexes form cooperatively with the Hsp90 co-chaperones Pp5 and FKBPs. 2020 Jul 1 4
8 29941666 Chaperone Activity and Dimerization Properties of Hsp90α and Hsp90β in Glucocorticoid Receptor Activation by the Multiprotein Hsp90/Hsp70-Dependent Chaperone Machinery. 2018 Sep 5
9 28700526 Urinary Macrophage Migration Inhibitory Factor as a Noninvasive Biomarker in Pediatric Henoch-Schönlein Purpura Nephritis. 2017 Aug 1
10 27769261 Steroid resistance in COPD is associated with impaired molecular chaperone Hsp90 expression by pro-inflammatory lymphocytes. 2016 Oct 21 3
11 28508980 An adult case of severe steroid-resistant Henoch-Schönlein purpura nephritis treated with intravenous cyclophosphamide and tonsillectomy. 2016 Nov 1
12 25986567 Steroid Receptor-Associated Immunophilins: Candidates for Diverse Drug-Targeting Approaches in Disease. 2015 2
13 24171710 Leflunomide in addition to steroids improves proteinuria and renal function in adult Henoch-Schoenlein nephritis with nephrotic proteinuria. 2014 Feb 1
14 22447868 Fluorescent protein-labeled glucocorticoid receptor alpha isoform trafficking in cultured human trabecular meshwork cells. 2012 May 17 2
15 21799260 FKBP immunophilins and Alzheimer's disease: a chaperoned affair. 2011 Aug 1
16 21968922 Biochemical reconstitution of steroid receptor•Hsp90 protein complexes and reactivation of ligand binding. 2011 Sep 21 4
17 20166544 [Adult case of severe Henoch-Schönlein purpura associated with steroid-resistant nephrotic syndrome successfully treated with intravenous cyclophosphamide]. 2010 1
18 20829124 High-yield expression and purification of the Hsp90-associated p23, FKBP52, HOP and SGTα proteins. 2010 Oct 15 1
19 19581287 Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta. 2009 Sep 1
20 18573821 Patients with multiple sclerosis resisted to glucocorticoid therapy: abnormal expression of heat-shock protein 90 in glucocorticoid receptor complex. 2008 Aug 2
21 16431970 Heat shock protein 90 is an essential molecular chaperone for nuclear transport of glucocorticoid receptor beta. 2006 Feb 1
22 16610357 Chaperoning of glucocorticoid receptors. 2006 3
23 15759036 Regulation of glucocorticoid receptor steroid binding and trafficking by the hsp90/hsp70-based chaperone machinery: implications for clinical intervention. 2005 May 1
24 16087666 Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone. 2005 Oct 7 2
25 15046863 Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation. 2004 Apr 7 1
26 15242338 Role of molecular chaperones in steroid receptor action. 2004 2
27 12563018 Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery. 2003 Feb 1
28 12807878 Visualization and mechanism of assembly of a glucocorticoid receptor.Hsp70 complex that is primed for subsequent Hsp90-dependent opening of the steroid binding cleft. 2003 Sep 12 5
29 12897402 Stress protein expression in the Alzheimer-diseased choroid plexus. 2003 Jun 1
30 12093808 Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly. 2002 Sep 13 6
31 11123263 Heat-shock factor-1, steroid hormones, and regulation of heat-shock protein expression in the heart. 2001 Jan 1
32 11146632 The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins. 2001 Jan 1
33 11170435 Evidence for iterative ratcheting of receptor-bound hsp70 between its ATP and ADP conformations during assembly of glucocorticoid receptor.hsp90 heterocomplexes. 2001 Jan 30 5
34 11677765 Glucocorticoid receptor and heat shock protein 90 in peripheral blood mononuclear cells from asthmatics. 2001 Oct 2
35 11803001 [Glucocorticoid receptor and HSP 90 mRNA expression in peripheral blood mononuclear cell from steroid resistant asthmatics]. 2001 Jul 2
36 10702249 The Hsp organizer protein hop enhances the rate of but is not essential for glucocorticoid receptor folding by the multiprotein Hsp90-based chaperone system. 2000 Mar 10 4
37 10764743 Stepwise assembly of a glucocorticoid receptor.hsp90 heterocomplex resolves two sequential ATP-dependent events involving first hsp70 and then hsp90 in opening of the steroid binding pocket. 2000 Jun 16 6
38 9880522 Neuronal nitric-oxide synthase is regulated by the Hsp90-based chaperone system in vivo. 1999 Jan 15 3
39 9990042 The molecular chaperone Hsp90 can negatively regulate the activity of a glucocorticosteroid-dependent promoter. 1999 Feb 16 1
40 10567384 Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery. 1999 Nov 26 1
41 10597896 Interactions of Hsp90 with histones and related peptides. 1999 2
42 9148915 Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation. 1997 May 16 7
43 9183567 Steroid receptor interactions with heat shock protein and immunophilin chaperones. 1997 Jun 2
44 9228040 The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin. 1997 Jul 25 1
45 9261129 Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70. 1997 Aug 22 5
46 8621522 Use of the thiol-specific derivatizing agent N-iodoacetyl-3-[125I]iodotyrosine to demonstrate conformational differences between the unbound and hsp90-bound glucocorticoid receptor hormone binding domain. 1996 Apr 12 2
47 8776730 Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. 1996 Jun 2
48 8856970 Molecular chaperoning of steroid hormone receptors. 1996 1
49 8939864 Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23. 1996 Dec 6 1
50 7625750 Connection between immunosuppressants and steroids via HSP90. 1995 Jun 12 1