2-chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamide

adenosine A3 receptor ; Homo sapiens







16 Article(s)
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1 35039871 2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines. 2022 Mar 2
2 35215276 A3 Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity. 2022 Jan 28 1
3 34660262 A3 Adenosine and P2X7 Purinergic Receptors as New Targets for an Innovative Pharmacological Therapy of Malignant Pleural Mesothelioma. 2021 1
4 34671996 Randomised clinical trial: A phase 2 double-blind study of namodenoson in non-alcoholic fatty liver disease and steatohepatitis. 2021 Dec 2
5 31714673 Activation of adenosine A3 receptor inhibits inflammatory cytokine production in colonic mucosa of patients with ulcerative colitis by down-regulating the nuclear factor-kappa B signaling. 2020 Jan 1
6 29170977 Species differences and mechanism of action of A3 adenosine receptor allosteric modulators. 2018 Mar 1
7 29309765 Molecular dissection of the human A3 adenosine receptor coupling with β-arrestin2. 2018 Feb 1
8 30292756 Probing structure-activity relationship in β-arrestin2 recruitment of diversely substituted adenosine derivatives. 2018 Dec 2
9 21520073 P-glycoprotein mediates resistance to A3 adenosine receptor agonist 2-chloro-N6-(3-iodobenzyl)-adenosine-5'-n-methyluronamide in human leukemia cells. 2012 Feb 1
10 22878643 The adenosine A3 receptor agonist Cl-IB-MECA induces cell death through Ca²⁺/ROS-dependent down regulation of ERK and Akt in A172 human glioma cells. 2012 Dec 3
11 19161279 A series of 2,4-disubstituted quinolines as a new class of allosteric enhancers of the adenosine A3 receptor. 2009 Feb 26 1
12 19284749 Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor. 2009 Apr 9 1
13 19639281 Medicinal chemistry of the A3 adenosine receptor: agonists, antagonists, and receptor engineering. 2009 1
14 18059189 Cl-IB-MECA inhibits human thyroid cancer cell proliferation independently of A3 adenosine receptor activation. 2008 Feb 2
15 18079280 Dual purinergic synaptic transmission in the human enteric nervous system. 2008 Feb 2
16 16051194 A novel adenosine analog, thio-Cl-IB-MECA, induces G0/G1 cell cycle arrest and apoptosis in human promyelocytic leukemia HL-60 cells. 2005 Sep 15 1