1-isopropyldiazen-1-ium-1,2-diolate

p21 (RAC1) activated kinase 1 ; Homo sapiens







23 Article(s)
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1 33495806 P21‑activated kinase 1 mediates angiotensin II‑induced differentiation of human atrial fibroblasts via the JNK/c‑Jun pathway. 2021 Mar 1
2 34403739 Amyloid-β induced membrane damage instigates tunneling nanotube-like conduits by p21-activated kinase dependent actin remodulation. 2021 Dec 1 2
3 32240651 PAK1 inhibitor IPA-3 mitigates metastatic prostate cancer-induced bone remodeling. 2020 Jul 1
4 31304555 Targeting Phosphorylation of p21-activated Kinase 1 at Thr423 Induces Cell Cycle Arrest and Apoptosis in Cutaneous T-cell Lymphoma Cells. 2019 Oct 1 2
5 31516713 Effect of P21-activated kinase 1 (PAK-1) inhibition on cancer cell growth, migration, and invasion. 2019 Oct 3
6 31614827 Simultaneous Inhibition of BCR-ABL1 Tyrosine Kinase and PAK1/2 Serine/Threonine Kinase Exerts Synergistic Effect against Chronic Myeloid Leukemia Cells. 2019 Oct 12 1
7 28972183 The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)-mediated glucose uptake into skeletal muscle cells. 2017 Nov 17 2
8 25956913 Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis. 2015 May 9 2
9 26255026 Cx43 increases serum induced filopodia formation via activation of p21-activated protein kinase 1. 2015 Nov 1
10 26379399 β-elemene enhances the radiosensitivity of gastric cancer cells by inhibiting Pak1 activation. 2015 Sep 14 3
11 24844382 Uptake of Shiga-toxigenic Escherichia coli SubAB by HeLa cells requires an actin- and lipid raft-dependent pathway. 2014 Oct 1
12 25174975 Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer. 2014 Aug 29 1
13 23153508 Rac1/PAK1 signaling promotes epithelial-mesenchymal transition of podocytes in vitro via triggering β-catenin transcriptional activity under high glucose conditions. 2013 Feb 2
14 23246867 A p21-activated kinase (PAK1) signaling cascade coordinately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells. 2013 Mar 15 4
15 23361053 Regulation of tamoxifen sensitivity by a PAK1-EBP1 signalling pathway in breast cancer. 2013 Feb 19 1
16 23894351 IPA-3 inhibits the growth of liver cancer cells by suppressing PAK1 and NF-κB activation. 2013 2
17 25034104 p21-activated kinase inhibitors. 2013 1
18 22369945 Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity. 2012 Mar 16 1
19 22869096 The response to PAK1 inhibitor IPA3 distinguishes between cancer cells with mutations in BRAF and Ras oncogenes. 2012 Jul 4
20 21969371 Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo. 2011 Dec 2 2
21 22096607 p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112. 2011 1
22 19723886 An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently. 2009 Sep 1
23 18420139 An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase. 2008 Apr 1