| 1 |
33713301 | Protective Effects of Novel Substituted Triazinoindole Inhibitors of Aldose Reductase and Epalrestat in Neuron-like PC12 Cells and BV2 Rodent Microglial Cells Exposed to Toxic Models of Oxidative Stress: Comparison with the Pyridoindole Antioxidant Stobadine. | 2021 Jun |
1 |
| 2 |
34738094 | Role of the Polyol Pathway in Locomotor Recovery and Wallerian Degeneration after Spinal Cord Contusion Injury. | 2021 |
1 |
| 3 |
30109747 | Artichoke leaf extract, as AKR1B1 inhibitor, decreases sorbitol level in the rat eye lenses under high glucose conditions ex vivo. | 2018 Dec |
2 |
| 4 |
25986969 | The inhibitory effect of Isoflavones isolated from Caesalpinia pulcherrima on aldose reductase in STZ induced diabetic rats. | 2015 Jul 25 |
2 |
| 5 |
26272532 | Effects of aldose reductase inhibitor on microneurographically assessed peripheral sympathetic nerve activity in rats. | 2015 Dec |
1 |
| 6 |
26291727 | A novel carboxymethylated mercaptotriazinoindole inhibitor of aldose reductase interferes with the polyol pathway in streptozotocin-induced diabetic rats. | 2015 |
1 |
| 7 |
25985564 | A novel zwitterionic inhibitor of aldose reductase interferes with polyol pathway in ex vivo and in vivo models of diabetic complications. | 2014 Oct |
1 |
| 8 |
22710095 | Osmotic stress, not aldose reductase activity, directly induces growth factors and MAPK signaling changes during sugar cataract formation. | 2012 Aug |
2 |
| 9 |
21376710 | Aldose reductase deficiency protects sugar-induced lens opacification in rats. | 2011 May 30 |
3 |
| 10 |
19902381 | The anti-necrosis role of hypoxic preconditioning after acute anoxia is mediated by aldose reductase and sorbitol pathway in PC12 cells. | 2010 Jul |
1 |
| 11 |
20197634 | Hyperglycemia impairs acetylcholine-induced vasodilation of retinal arterioles through polyol pathway-independent mechanisms in rats. | 2010 |
1 |
| 12 |
18569331 | In vitro aldose reductase inhibitory activity of some flavonyl-2,4-thiazolidinediones. | 2008 Jun |
3 |
| 13 |
16718375 | Long-term effect of Trigonella foenum graecum and its combination with sodium orthovanadate in preventing histopathological and biochemical abnormalities in diabetic rat ocular tissues. | 2006 Sep |
1 |
| 14 |
15755558 | A potent sorbitol dehydrogenase inhibitor exacerbates sympathetic autonomic neuropathy in rats with streptozotocin-induced diabetes. | 2005 Apr |
1 |
| 15 |
15171691 | Alteration of urinary sorbitol excretion in WBN-kob diabetic rats - treatment with an aldose reductase inhibitor. | 2004 Jun |
1 |
| 16 |
15321028 | Anticataract activity of analogs of a sorbitol dehydrogenase inhibitor. | 2004 Aug |
1 |
| 17 |
12604220 | Regulation of aldose reductase and the polyol pathway activity by nitric oxide. | 2003 Feb 1 |
3 |
| 18 |
12663474 | Diabetes can alter the signal transduction pathways in the lens of rats. | 2003 Apr |
1 |
| 19 |
12684816 | Colocalization of polyol-metabolizing enzymes and immunological detection of fructated proteins in the female reproductive system of the rat. | 2003 Apr |
1 |
| 20 |
12773033 | A highly selective, non-hydantoin, non-carboxylic acid inhibitor of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran- 2-sulfonyl)-2-H-pyridazin-3-one. | 2003 Jun 5 |
1 |
| 21 |
12881532 | Aldose reductase induced by hyperosmotic stress mediates cardiomyocyte apoptosis: differential effects of sorbitol and mannitol. | 2003 Oct 3 |
2 |
| 22 |
14551351 | Osmoregulation of aldose reductase and sorbitol dehydrogenase in cultivated interstitial cells of rat renal inner medulla. | 2003 Nov |
1 |
| 23 |
12167599 | Expression of aldose reductase in developing rat kidney. | 2002 Sep |
2 |
| 24 |
11520112 | Biochemical and morphological changes during development of sugar cataract in Otsuka Long-Evans Tokushima fatty (OLETF) rat. | 2001 Sep |
1 |
| 25 |
12035507 | [Diabetic neuropathies. Metabolism of sorbitol in sciatic nerve tissue in streptozotocin diabetes]. | 2001 Sep-Oct |
1 |
| 26 |
10068486 | Iris vasculopathy in galactose-fed rats. | 1999 Feb |
1 |
| 27 |
10440899 | Characterization of polyol pathway in Schwann cells isolated from adult rat sciatic nerves. | 1999 Aug 15 |
3 |
| 28 |
9686698 | Reduced nerve blood flow in diabetic rats: relationship to nitric oxide production and inhibition of aldose reductase. | 1998 Jul |
1 |
| 29 |
9695123 | Effects of two aldose reductase inhibitors upon sorbitol output, D-glucose metabolism and insulin release in islets from normal and hereditarily diabetic rats. | 1998 Jun |
1 |
| 30 |
9716718 | Expression of Na+/Cl-/betaine and Na+/myo-inositol transporters, aldose reductase and sorbitol dehydrogenase in macula densa cells of the kidney. | 1998 Oct |
1 |
| 31 |
9949255 | Rat renal expression of mRNA coding for aldose reductase and sorbitol dehydrogenase and its osmotic regulation in inner medullary collecting duct cells. | 1998 |
2 |
| 32 |
10599142 | [Correction of diabetic neuropathies using aldose reductase inhibitors and pikamilon]. | 1998 Nov-Dec |
1 |
| 33 |
10959252 | Correction of nerve conduction and endoneurial blood flow deficits by the aldose reductase inhibitor, tolrestat, in diabetic rats. | 1998 |
2 |
| 34 |
9505366 | [Role of aldose reductase inhibitors in the development of peripheral neuropathy in experimental diabetes]. | 1997 May-Jun |
1 |
| 35 |
8733731 | Aldose reductase and sorbitol dehydrogenase activities in diabetic brain: in vivo kinetic studies using 19F 3-FDG NMR in rats. | 1996 Feb 29 |
2 |
| 36 |
8785398 | Aldose reductase and myo-inositol transporter mRNA are independently regulated in rat renal medulla. | 1996 Feb |
1 |
| 37 |
8809342 | Role of lipid aldehydes in cataractogenesis: 4-hydroxynonenal-induced cataract. | 1996 Jun |
1 |
| 38 |
8872957 | Potassium depletion modulates aldose reductase mRNA in rat renal inner medulla. | 1996 Sep |
1 |
| 39 |
8889497 | Activation of aldose reductase in rat lens and metal-ion chelation by aldose reductase inhibitors and lipoic acid. | 1996 Oct |
2 |
| 40 |
8954157 | Effect of hyperglycemia on the polyol pathway in rat kidney during the perinatal period. | 1996 Nov 15 |
1 |
| 41 |
7503236 | Renal inner medullary sorbitol metabolism. | 1995 Nov |
1 |
| 42 |
7564101 | Time-dependent aspects of osmolyte changes in rat kidney, urine, blood and lens with sorbinil and galactose feeding. | 1995 Aug |
2 |
| 43 |
7752919 | Acetyl-L-carnitine corrects the altered peripheral nerve function of experimental diabetes. | 1995 May |
1 |
| 44 |
7859946 | Inhibition of sorbitol dehydrogenase. Effects on vascular and neural dysfunction in streptozocin-induced diabetic rats. | 1995 Feb |
1 |
| 45 |
8786718 | Identification of galactitol 2-phosphate and galactitol 3-phosphate in the lens of galactose-fed rats. | 1995 Dec |
1 |
| 46 |
8027986 | Novel spirosuccinimide aldose reductase inhibitors derived from isoquinoline-1,3-diones: 2-[(4-bromo-2-fluorophenyl)methyl]-6- fluorospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrone and congeners. 1. | 1994 Jun 24 |
1 |
| 47 |
8040341 | The linked roles of nitric oxide, aldose reductase and, (Na+,K+)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat. | 1994 Aug |
1 |
| 48 |
8129726 | Control of glucokinase translocation in rat hepatocytes by sorbitol and the cytosolic redox state. | 1994 Feb 15 |
1 |
| 49 |
8241288 | Control of sorbitol metabolism in renal inner medulla of diabetic rats: regulation by substrate, cosubstrate and products of the aldose reductase reaction. | 1993 Nov 25 |
2 |
| 50 |
8325441 | Acetyl-L-carnitine corrects electroretinographic deficits in experimental diabetes. | 1993 Aug |
1 |