| 1 |
35013861 | Bioactive components to inhibit foam cell formation in atherosclerosis. | 2022 Mar |
1 |
| 2 |
34153284 | Carboxylesterase 1d (Ces1d) does not contribute to cholesteryl ester hydrolysis in the liver. | 2021 |
2 |
| 3 |
34234263 | Copy number variation in the CES1 gene and the risk of non-alcoholic fatty liver in a Chinese Han population. | 2021 Jul 7 |
2 |
| 4 |
34436484 | Acyl-Coenzyme A: Cholesterol Acyltransferase (ACAT) in Cholesterol Metabolism: From Its Discovery to Clinical Trials and the Genomics Era. | 2021 Aug 14 |
4 |
| 5 |
32258948 | Hepatocyte-Specific Expression of Human Carboxylesterase 1 Attenuates Diet-Induced Steatohepatitis and Hyperlipidemia in Mice. | 2020 Apr |
1 |
| 6 |
32466188 | Genetic Analysis Reveals a Significant Contribution of CES1 to Prostate Cancer Progression in Taiwanese Men. | 2020 May 25 |
2 |
| 7 |
30901224 | Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion. | 2019 May 3 |
1 |
| 8 |
29247837 | Cholesterol ester hydrolase inhibitors reduce the production of synaptotoxic amyloid-β oligomers. | 2018 Mar |
1 |
| 9 |
29321244 | Silencing carboxylesterase 1 in human THP-1 macrophages perturbs genes regulated by PPARγ/RXR and RAR/RXR: down-regulation of CYP27A1-LXRα signaling. | 2018 Feb 9 |
4 |
| 10 |
28349866 | Bolstering cholesteryl ester hydrolysis in liver: A hepatocyte-targeting gene delivery strategy for potential alleviation of atherosclerosis. | 2017 Jun |
2 |
| 11 |
29050765 | Alveolar macrophages from tuberculosis patients display an altered inflammatory gene expression profile. | 2017 Dec |
1 |
| 12 |
29911769 | [Design and development of fluorescent probe substrates for carboxylesterase 1 using BODIPY as the basic fluorophore]. | 2017 Jan |
2 |
| 13 |
24512105 | Association between copy number variation losses and alcohol dependence across African American and European American ethnic groups. | 2014 May |
1 |
| 14 |
23468884 | Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function. | 2013 |
2 |
| 15 |
23744992 | Liver-specific cholesteryl ester hydrolase deficiency attenuates sterol elimination in the feces and increases atherosclerosis in ldlr-/- mice. | 2013 Aug |
1 |
| 16 |
24028971 | MiR-9 reduces human acyl-coenzyme A:cholesterol acyltransferase-1 to decrease THP-1 macrophage-derived foam cell formation. | 2013 Nov |
1 |
| 17 |
24051439 | A simple method for the determination of the cholesterol esterase activity. | 2013 |
1 |
| 18 |
22262001 | Early steps in reverse cholesterol transport: cholesteryl ester hydrolase and other hydrolases. | 2012 Apr |
1 |
| 19 |
21081832 | Depot-specific expression of lipolytic genes in human adipose tissues--association among CES1 expression, triglyceride lipase activity and adiposity. | 2011 |
1 |
| 20 |
19878739 | Macrophage cholesteryl ester mobilization and atherosclerosis. | 2010 Jan-Feb |
2 |
| 21 |
20530478 | Activity-based protein profiling identifies a host enzyme, carboxylesterase 1, which is differentially active during hepatitis C virus replication. | 2010 Aug 13 |
1 |
| 22 |
20947831 | The critical role of neutral cholesterol ester hydrolase 1 in cholesterol removal from human macrophages. | 2010 Nov 26 |
1 |
| 23 |
19062296 | Comparison of benzil and trifluoromethyl ketone (TFK)-mediated carboxylesterase inhibition using classical and 3D-quantitative structure-activity relationship analysis. | 2009 Jan 1 |
1 |
| 24 |
19293413 | ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial. | 2009 Mar 18 |
1 |
| 25 |
20403742 | Horse carboxylesterases: evidence for six CES1 and four families of CES genes on chromosome 3. | 2009 Mar |
1 |
| 26 |
18000807 | Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT). | 2008 Jan 1 |
1 |
| 27 |
18078940 | Conjugated and non-conjugated octadecaenoic acids affect differently intestinal acyl coenzyme A: cholesterol acyltransferase activity. | 2008 May |
2 |
| 28 |
18762277 | Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages. | 2008 Oct |
3 |
| 29 |
18779653 | Inhibition of acyl-coenzyme A:cholesterol acyltransferase stimulates cholesterol efflux from macrophages and stimulates farnesoid X receptor in hepatocytes. | 2008 Aug 31 |
6 |
| 30 |
16971496 | Stable overexpression of human macrophage cholesteryl ester hydrolase results in enhanced free cholesterol efflux from human THP1 macrophages. | 2007 Jan |
16 |
| 31 |
17123760 | Glabrol, an acyl-coenzyme A: cholesterol acyltransferase inhibitor from licorice roots. | 2007 Apr 4 |
1 |
| 32 |
17950700 | Cholesterol regulates ACAT2 gene expression and enzyme activity in human hepatoma cells. | 2007 Dec 14 |
2 |
| 33 |
16495773 | Pharmacological profile of SMP-797, a novel acyl-coenzyme a: cholesterol acyltransferase inhibitor with inducible effect on the expression of low-density lipoprotein receptor. | 2006 Feb |
1 |
| 34 |
16554527 | Effect of ACAT inhibition on the progression of coronary atherosclerosis. | 2006 Mar 23 |
1 |
| 35 |
16753029 | Cholesterol sensing, trafficking, and esterification. | 2006 |
2 |
| 36 |
16832167 | And then there were acyl coenzyme A:cholesterol acyl transferase inhibitors. | 2006 Aug |
1 |
| 37 |
16962139 | Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1. | 2006 Oct 13 |
2 |
| 38 |
16024911 | Redistribution of macrophage cholesteryl ester hydrolase from cytoplasm to lipid droplets upon lipid loading. | 2005 Oct |
1 |
| 39 |
16081098 | Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. | 2005 Sep 9 |
1 |
| 40 |
16131527 | Human liver cholesteryl ester hydrolase: cloning, molecular characterization, and role in cellular cholesterol homeostasis. | 2005 Nov 17 |
1 |
| 41 |
16503866 | Inhibitors of acyl-coenzyme a: cholesterol acyltransferase. | 2005 Dec |
3 |
| 42 |
15164335 | Cholesterol absorption and hepatic acyl-coenzyme A:cholesterol acyltransferase activity play major roles in lipemic response to dietary cholesterol and fat in laboratory opossums. | 2004 Jun |
2 |
| 43 |
15317807 | Effects of 25-hydroxycholesterol on cholesterol esterification and sterol regulatory element-binding protein processing are dissociable: implications for cholesterol movement to the regulatory pool in the endoplasmic reticulum. | 2004 Nov 5 |
5 |
| 44 |
15533865 | Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions. | 2004 Nov 23 |
1 |
| 45 |
12533546 | Cholesterol is superior to 7-ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1. | 2003 Mar 28 |
2 |
| 46 |
12725862 | Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition. | 2003 Apr |
3 |
| 47 |
12773168 | Human carboxylesterase 1: from drug metabolism to drug discovery. | 2003 Jun |
1 |
| 48 |
12837853 | Mobilization of cytoplasmic CE droplets by overexpression of human macrophage cholesteryl ester hydrolase. | 2003 Oct |
1 |
| 49 |
11684695 | Mutant acyl-coenzyme A:cholesterol acyltransferase 1 devoid of cysteine residues remains catalytically active. | 2002 Jan 4 |
1 |
| 50 |
11772425 | Inhibition of acyl coenzyme A-cholesterol acyltransferase: a possible treatment of atherosclerosis? | 2002 Jan |
2 |