Dabigatran

carboxylesterase 1 ; Homo sapiens







18 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33179295 The impact of ABCB1 and CES1 polymorphisms on dabigatran pharmacokinetics and pharmacodynamics in patients with atrial fibrillation. 2021 May 3
2 33440670 Pharmacogenetics of Direct Oral Anticoagulants: A Systematic Review. 2021 Jan 11 1
3 33935512 The Impact of ABCB1 and CES1 Polymorphisms on Dabigatran Pharmacokinetics in Healthy Chinese Subjects. 2021 2
4 32134727 Effect of CES1 and ABCB1 genotypes on the pharmacokinetics and clinical outcomes of dabigatran etexilate in patients with atrial fibrillation and chronic kidney disease. 2020 Mar 5 2
5 32564268 Effect of Sex, Use of Pantoprazole and Polymorphisms in SLC22A1, ABCB1, CES1, CYP3A5 and CYP2D6 on the Pharmacokinetics and Safety of Dabigatran. 2020 Aug 1
6 32899083 Left atrial appendage thrombus formation in a patient with atrial fibrillation on dabigatran therapy associated with CES1 and ABCB1 genetic polymorphisms: A case report. 2020 Sep 4 4
7 30658513 Pharmacogenomics of Novel Direct Oral Anticoagulants: Newly Identified Genes and Genetic Variants. 2019 Jan 17 1
8 30850966 Genetic determinants of dabigatran safety (CES1 gene rs2244613 polymorphism) in the Russian population: multi-ethnic analysis. 2019 Jun 2
9 31104266 A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Model of Dabigatran Etexilate, Dabigatran and Dabigatran Glucuronide in Healthy Adults and Renally Impaired Patients. 2019 Dec 2
10 29867495 Left Atrial Appendage Thrombus Formation in a Patient on Dabigatran Therapy Associated With ABCB1 and CES-1 Genetic Defect. 2018 2
11 30100750 The impact of ABCB1 (rs1045642 and rs4148738) and CES1 (rs2244613) gene polymorphisms on dabigatran equilibrium peak concentration in patients after total knee arthroplasty. 2018 1
12 27261537 Pharmacogenetics of dabigatran etexilate interindividual variability. 2016 Aug 3
13 27614009 Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender. 2016 Nov 1 13
14 24212377 Impact of endogenous esterase activity on in vitro p-glycoprotein profiling of dabigatran etexilate in Caco-2 monolayers. 2014 Feb 5
15 24212379 Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis. 2014 Feb 6
16 24988246 The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect. 2014 1
17 23239178 Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the investigation of in vitro dabigatran etexilate metabolism. 2013 Feb 2
18 23467860 Genetic determinants of dabigatran plasma levels and their relation to bleeding. 2013 Apr 2 1