Simvastatin

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angiotensinogen ; Rattus norvegicus







28 Article(s)
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1 29460135 Simvastatin reduces adrenal catecholamine secretion evoked by stimulation of cholinergic nicotinic and angiotensinergic AT1 receptors. 2018 Mar 2
2 25492829 The effect of simvastatin and pravastatin on arterial blood pressure, baroreflex, vasoconstrictor, and hypertensive effects of angiotensin II in Sprague-Dawley rats. 2014 Dec 4
3 22083280 Simvastatin ameliorates angiotensin II-induced endothelial dysfunction through restoration of Rho-BH4-eNOS-NO pathway. 2012 Feb 2
4 22233179 Oral simvastatin reduces the hypertensive response to air-jet stress. 2012 Apr 2
5 19515066 Simvastatin inhibits angiotensin II-induced cardiac cell hypertrophy: role of Homer 1a. 2010 Jan 5
6 20117462 Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation. 2010 Feb 2 1
7 20489687 Simvastatin reduces pressor response to centrally administered angiotensin II. 2010 Sep 3
8 21152444 Statins inhibit angiotensin II/Smad pathway and related vascular fibrosis, by a TGF-β-independent process. 2010 Nov 30 1
9 19298698 Synergism of simvastatin with losartan prevents angiotensin II-induced cardiomyocyte apoptosis in vitro. 2009 Apr 4
10 18172037 Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling. 2008 Jan 22 1
11 17161379 Effects of statin treatment and withdrawal on angiotensin II-induced phosphorylation of p38 MAPK and ERK1/2 in cultured vascular smooth muscle cells. 2007 Feb 2 2
12 17463319 Angiotensin II increases expression of alpha1C subunit of L-type calcium channel through a reactive oxygen species and cAMP response element-binding protein-dependent pathway in HL-1 myocytes. 2007 May 25 2
13 17592071 HMG-CoA reductase inhibitors decrease angiotensin II-induced vascular fibrosis: role of RhoA/ROCK and MAPK pathways. 2007 Aug 1
14 17878758 Simvastatin reverses target organ damage and oxidative stress in Angiotensin II hypertension: comparison with apocynin, tempol, and hydralazine. 2007 Sep 4
15 18091590 Upregulation of angiotensin II-AT1 receptors during statin withdrawal in vascular smooth muscle cells. 2007 Dec 2
16 16449352 Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells. 2006 Jul 3
17 16628357 [Simvastatin inhibits hypertension-induced cardiac hypertrophy in rats through activation of heme oxygenase-1/carbon monoxide pathway]. 2006 Apr 25 1
18 16280288 Simvastatin and losartan enhance nitric oxide and reduce oxidative stress in salt-induced hypertension. 2005 Nov 1
19 15213258 Simvastatin modulates angiotensin II signaling pathway by preventing Rac1-mediated upregulation of p27. 2004 Jul 7
20 14512087 HMG CoA reductase inhibitor suppresses the expression of tissue factor and plasminogen activator inhibitor-1 induced by angiotensin II in cultured rat aortic endothelial cells. 2003 Jun 1 3
21 12154104 Simvastatin prevents angiotensin II-induced cardiac alteration and oxidative stress. 2002 Aug 7
22 11714734 Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy. 2001 Nov 5
23 11794990 [Simvastatin attenuates cardiovascular effects and oxidative stress induced by angiotensin II]. 2001 Nov 3
24 11868908 Simvastatin induces apoptosis of cultured rat cardiomyocytes. 2001 1
25 10413074 Differential effects of pravastatin, simvastatin, and atorvastatin on Ca2+ release and vascular reactivity. 1999 Jul 1
26 10440099 Lovastatin prevents angiotensin II-induced cardiac hypertrophy in cultured neonatal rat heart cells. 1999 Jul 2 2
27 10561812 Simvastatin inhibits cardiac hypertrophy and angiotensin-converting enzyme activity in rats with aortic stenosis. 1999 Nov 1
28 12013483 Inhibition of smooth muscle cell calcium mobilization and aortic ring contraction by lactone vastatins. 1996 Jan 3