olmesartan

angiotensinogen ; Rattus norvegicus







49 Article(s)
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1 32106816 High-dose nitrate therapy recovers the expression of subtypes α1 and β-adrenoceptors and Ang II receptors of the renal cortex in rats with myocardial infarction-induced heart failures. 2020 Feb 27 1
2 32585603 The effect of olmesartan on aortic intimal thickening after balloon injury through Apelin/APJ. 2020 Nov - Dec 2
3 28656296 The ACE2-Ang (1-7)-Mas receptor axis attenuates cardiac remodeling and fibrosis in post-myocardial infarction. 2017 Aug 2
4 26763849 The angiotensin II receptor antagonist, losartan, enhances regulator of G protein signaling 2 mRNA expression in vascular smooth muscle cells of Wistar rats. 2016 May 2
5 24817138 Role of intrarenal (pro)renin receptor in ischemic acute kidney injury in rats. 2015 Apr 1
6 25487981 Effects of olmesartan therapy on the expression of lung adrenoceptors in rats with chronic heart failure. 2015 Mar 2
7 24291173 Olmesartan protects against oxidative stress possibly through the Nrf2 signaling pathway and inhibits inflammation in daunorubicin-induced nephrotoxicity in rats. 2014 Feb 1
8 24770651 Regulation of apelin and its receptor expression in adipose tissues of obesity rats with hypertension and cultured 3T3-L1 adipocytes. 2014 2
9 24847907 Mitochondrial KATP channel involvement in angiotensin II-induced autophagy in vascular smooth muscle cells. 2014 Jul 2
10 24910532 Detailed localization of augmented angiotensinogen mRNA and protein in proximal tubule segments of diabetic kidneys in rats and humans. 2014 1
11 25089522 Cytosolic CARP promotes angiotensin II- or pressure overload-induced cardiomyocyte hypertrophy through calcineurin accumulation. 2014 2
12 23459599 Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats. 2013 May 2
13 23698111 Angiotensin-converting enzyme inhibitor does not suppress renal angiotensin II levels in angiotensin I-infused rats. 2013 2
14 24342995 Mechanisms with clinical implications for atrial fibrillation-associated remodeling: cathepsin K expression, regulation, and therapeutic target and biomarker. 2013 Dec 16 1
15 22318512 Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats. 2012 May 1
16 22496409 Enhanced intrarenal receptor-mediated prorenin activation in chronic progressive anti-thymocyte serum nephritis rats on high salt intake. 2012 Jul 1 1
17 21536991 Activation of estrogen receptor-α and of angiotensin-converting enzyme 2 suppresses ischemic brain damage in oophorectomized rats. 2011 Jun 2
18 21602711 Olmesartan ameliorates peripheral nerve dysfunction in Zucker diabetic fatty rats. 2011 Jul 2
19 21716329 Angiotensin II shifts insulin signaling into vascular remodeling from glucose metabolism in vascular smooth muscle cells. 2011 Oct 1
20 20601457 ANG II inhibits insulin-mediated production of PI 3,4,5-trisphosphates via a Ca2+-dependent but PKC-independent pathway in the cardiomyocytes. 2010 Sep 1
21 20827339 Inhibitory effects of olmesartan on catecholamine secretion from the perfused rat adrenal medulla. 2010 Aug 2
22 20876084 Beneficial effects of olmesartan, an angiotensin II receptor type 1 antagonist, in rats with dilated cardiomyopathy. 2010 Nov 1
23 20965209 Aging impairs myocardium-induced dilation in coronary arterioles: role of hydrogen peroxide and angiotensin. 2010 Nov-Dec 1
24 19171689 Olmesartan improves left ventricular function in pressure-overload hypertrophied rat heart by blocking angiotensin II receptor with synergic effects of upregulation of angiotensin converting enzyme 2. 2009 Apr 1
25 19261744 Angiotensin II type 1 receptor blocker attenuates the activation of ERK and NADPH oxidase by mechanical strain in mesangial cells in the absence of angiotensin II. 2009 May 1
26 19466524 Favorable cardiac and aortic remodeling in olmesartan-treated spontaneously hypertensive rats. 2009 May 1
27 19662023 Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats. 2009 Oct 1
28 18256306 Angiotensin II accelerates osteoporosis by activating osteoclasts. 2008 Jul 2
29 18360051 Olmesartan ameliorates progressive glomerular injury in subtotal nephrectomized rats through suppression of superoxide production. 2008 Feb 1
30 18583318 Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment. 2008 Aug 1
31 18633182 Cellular physiology of rat cardiac myocytes in cardiac fibrosis: in vitro simulation using the cardiac myocyte/cardiac non-myocyte co-culture system. 2008 Apr 2
32 18725581 Effect of olmesartan on tissue expression balance between angiotensin II receptor and its inhibitory binding molecule. 2008 Oct 5
33 16934905 Role of angiotensin II type-1 and type-2 receptors on vascular smooth muscle cell growth and glucose metabolism in diabetic rats. 2007 Mar 1
34 16331107 Opposing actions of angiotensin II type 1 and 2 receptors on plasma cholesterol levels in rats. 2006 Jan 2
35 16546478 Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance. 2006 Apr 2
36 16685209 Synergistic effect of mechanical stretch and angiotensin II on superoxide production via NADPH oxidase in vascular smooth muscle cells. 2006 Jun 1
37 16755152 Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan. 2006 Mar 1
38 16767106 Angiotensin II-dependent Src and Smad1 signaling pathway is crucial for the development of diabetic nephropathy. 2006 Sep 1
39 17345786 Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme. 2006 Nov 4
40 15867141 Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats. 2005 Jun 2
41 15963646 Angiotensin type 1 receptor blockage improves ischemic injury following transient focal cerebral ischemia. 2005 1
42 16053988 Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy. 2005 Jul 1
43 16143317 Chronic administration of olmesartan attenuates the exaggerated pressor response to glutamate in the rostral ventrolateral medulla of SHR. 2005 Oct 5 2
44 16416656 The angiotensin-II (AT-II) receptor blocker olmesartan reduces renal damage in animal models of hypertension and diabetes. 2005 1
45 16419651 Olmesartan ameliorates insulin sensitivity by modulating tumor necrosis factor-alpha and cyclic AMP in skeletal muscle. 2005 Sep 1
46 14732213 Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells. 2004 Jan 1 2
47 12871826 An angiotensin II type 1 receptor antagonist, olmesartan medoxomil, improves experimental liver fibrosis by suppression of proliferation and collagen synthesis in activated hepatic stellate cells. 2003 Jul 3
48 14574081 Effects of olmesartan, an angiotensin II receptor blocker, on mechanically-modulated genes in cardiac myocytes. 2003 May 1
49 8566137 Pharmacology of CS-866, a novel nonpeptide angiotensin II receptor antagonist. 1995 Oct 16 1