Valsartan

angiotensinogen ; Rattus norvegicus







97 Article(s)
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1 34075552 Sacubitril/Valsartan Decreases Atrial Fibrillation Susceptibility by Inhibiting Angiotensin II-Induced Atrial Fibrosis Through p-Smad2/3, p-JNK, and p-p38 Signaling Pathways. 2022 Feb 3
2 33779339 Time-Dependent Effects of Individual and Combined Treatments With Nebivolol, Lisinopril, and Valsartan on Blood Pressure and Vascular Reactivity to Angiotensin II and Norepinephrine. 2021 Sep 2
3 34400686 Cardioprotective effects of early intervention with sacubitril/valsartan on pressure overloaded rat hearts. 2021 Aug 16 2
4 34431038 Blocking angiotensin 2 receptor attenuates diabetic nephropathy via mitigating ANGPTL2/TL4/NF-κB expression. 2021 Sep 2
5 32466632 Regulation of epithelial mesenchymal transition by the renin-angiotensin system: a role for klotho in renal tubular epithelial cells. 2020 Jan-Feb 1
6 33425219 AT1R/GSK-3β/mTOR Signaling Pathway Involved in Angiotensin II-Induced Neuronal Apoptosis after HIE Both In Vitro and In Vivo. 2020 2
7 31030610 Strong and Sustained Antihypertensive Effect of Small Interfering RNA Targeting Liver Angiotensinogen. 2019 Jun 1
8 31803758 Activation of the Human Angiotensin-(1-12)-Chymase Pathway in Rats With Human Angiotensinogen Gene Transcripts. 2019 1
9 29620193 Influence of the interaction between Ac‑SDKP and Ang II on the pathogenesis and development of silicotic fibrosis. 2018 Jun 2
10 29981238 Angiotensin II, a stress-related neuropeptide in the CNS, facilitates micturition reflex in rats. 2018 Sep 1
11 26728369 [Valsartan inhibits angiotensin II-Notch signaling of mesangial cells induced by high glucose]. 2016 Jan 2
12 27050934 Valsartan attenuates intimal hyperplasia in balloon-injured rat aortic arteries through modulating the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis. 2016 May 15 2
13 25362207 Angiotensin receptor neprilysin inhibitor LCZ696 attenuates cardiac remodeling and dysfunction after myocardial infarction by reducing cardiac fibrosis and hypertrophy. 2015 Jan 1
14 25460028 Effects and underlying mechanisms of human opiorphin on cardiovascular activity in anesthetized rats. 2015 Feb 15 1
15 25823960 Novel mechanism of cardiac protection by valsartan: synergetic roles of TGF-β1 and HIF-1α in Ang II-mediated fibrosis after myocardial infarction. 2015 Aug 3
16 26195268 Angiotensin type 1 receptor mediates renal production and conversion of prostaglandins E2 to F2α in conscious diabetic rats. 2015 Dec 1
17 26202363 Valsartan Reduced Atrial Fibrillation Susceptibility by Inhibiting Atrial Parasympathetic Remodeling through MAPKs/Neurturin Pathway. 2015 1
18 26330760 Trichostatin A Modulates Angiotensin II-induced Vasoconstriction and Blood Pressure Via Inhibition of p66shc Activation. 2015 Sep 2
19 24420538 Aliskiren reduces myocardial ischemia-reperfusion injury by a bradykinin B2 receptor- and angiotensin AT2 receptor-mediated mechanism. 2014 Apr 3
20 24445059 Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation. 2014 Jan 3
21 24486428 Opiorphin increases blood pressure of conscious rats through renin-angiotensin system (RAS). 2014 May 1
22 25014676 Valsartan decreases neointimal hyperplasia in balloon-injured rat aortic arteries by upregulating HO-1 and inhibiting angiotensin II type 1 receptor. 2014 Aug 21 1
23 25431019 Angiotensin II acting on brain AT1 receptors induces adrenaline secretion and pressor responses in the rat. 2014 Nov 28 1
24 23190689 Powerful vascular protection by combining cilnidipine with valsartan in stroke-prone, spontaneously hypertensive rats. 2013 Apr 2
25 23288202 Downregulation of the cardiotrophin-1 gene expression by valsartan and spironolactone in hypertrophied heart rats in vivo and rat cardiomyocyte H9c2 cell line in vitro: a novel mechanism of cardioprotection. 2013 Apr 1
26 22222314 Restoration of the blood pressure circadian rhythm by direct renin inhibition and blockade of angiotensin II receptors in mRen2.Lewis hypertensive rats. 2012 Feb 3
27 22792802 [Effect of Astragali Radix injection on myocardial cell mitochondrial structure and function in process of reversing myocardial cell hypertrophy]. 2012 Apr 2
28 23141017 [Effects of valsartan on aortic angiotensin converting enzyme 2 expression after aortic balloon injury in rats]. 2012 Aug 1
29 21293118 Effects of an N-type calcium antagonist on angiotensin II-renin feedback. 2011 3
30 21355302 [Protective effect of valsartan or/and ligustrazine on hippocampal neuronal loss in rats with vascular dementia]. 2011 Jan 1
31 21418803 [Effect of valsartan on vasoconstriction induced by the chronic injury of the adventitia in the rat collared carotid artery]. 2011 Jan 3
32 19769609 (Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation. 2010 Mar 1
33 20175999 Effect of angiotensin II on the WNK-OSR1/SPAK-NCC phosphorylation cascade in cultured mpkDCT cells and in vivo mouse kidney. 2010 Mar 19 2
34 20571281 Role of Fosinopril and Valsartan on Klotho Gene Expression Induced by Angiotensin II in Rat Renal Tubular Epithelial Cells. 2010 5
35 19145780 p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats. 2009 Jan 3
36 19246637 Angiotensin II induces renal plasminogen activator inhibitor-1 and cyclooxygenase-2 expression post-transcriptionally via activation of the mRNA-stabilizing factor human-antigen R. 2009 Apr 2
37 19662023 Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats. 2009 Oct 1
38 17965735 Effects of angiotensin II blockade on inflammation-induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers. 2008 Jan 1
39 18023891 An angiotensin II receptor antagonist reduces inflammatory parameters in two models of colitis. 2008 Feb 7 2
40 18406589 Effect of total flavonoid fraction of Astragalus complanatus R. Brown on angiotensin II-induced portal-vein contraction in hypertensive rats. 2008 Sep 1
41 18560380 Angiotensin II promotes NO production, inhibits apoptosis and enhances adhesion potential of bone marrow-derived endothelial progenitor cells. 2008 Jul 1
42 18566342 Redox-sensitive signaling by angiotensin II involves oxidative inactivation and blunted phosphorylation of protein tyrosine phosphatase SHP-2 in vascular smooth muscle cells from SHR. 2008 Jul 18 1
43 18619357 [Changes of c-fos, c-jun mRNA expressions in cardiomyocyte hypertrophy induced by angiotensin II and effects of tanshinone II A]. 2008 Apr 1
44 18846332 Changes of c-fos and c-jun mRNA expression in angiotensin II-induced cardiomyocyte hypertrophy and effects of sodium tanshinone IIA sulfonate. 2008 Oct 2
45 18853116 Effect of sodium tanshinone II A sulfonate on cardiac myocyte hypertrophy and its underlying mechanism. 2008 Sep 1
46 19020766 Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan. 2008 Dec 2
47 19080339 Effect of valsartan on the expression of angiotensin II receptors in the lung of chronic antigen exposure rats. 2008 Nov 20 1
48 17068200 Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1. 2007 Feb 1
49 17211247 Pressor response induced by central angiotensin II is mediated by activation of Rho/Rho-kinase pathway via AT1 receptors. 2007 Feb 1
50 17533199 NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat. 2007 Aug 1