vandetanib

epidermal growth factor receptor ; Mus musculus







13 Article(s)
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1 27549668 Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation. 2016 Aug 5
2 22611027 Vandetanib, an inhibitor of VEGF receptor-2 and EGF receptor, suppresses tumor development and improves prognosis of liver cancer in mice. 2012 Jul 15 4
3 20629091 Targeted molecular therapy of head and neck squamous cell carcinoma with the tyrosine kinase inhibitor vandetanib in a mouse model. 2011 Mar 2
4 21220477 Targeted therapy of VEGFR2 and EGFR significantly inhibits growth of anaplastic thyroid cancer in an orthotopic murine model. 2011 Apr 15 1
5 18347145 Dual inhibition of VEGFR and EGFR signaling reduces the incidence and size of intestinal adenomas in Apc(Min/+) mice. 2008 Mar 2
6 18698025 Vandetanib inhibits growth of adenoid cystic carcinoma in an orthotopic nude mouse model. 2008 Aug 15 3
7 17639056 A transplantable human medullary thyroid carcinoma as a model for RET tyrosine kinase-driven tumorigenesis. 2007 Jun 2
8 17975157 Investigation of two dosing schedules of vandetanib (ZD6474), an inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling, in combination with irinotecan in a human colon cancer xenograft model. 2007 Nov 1 2
9 16052530 ZD6474 inhibits tumor growth and intraperitoneal dissemination in a highly metastatic orthotopic gastric cancer model. 2006 Jan 15 1
10 16299247 ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors. 2005 Nov 15 2
11 14760102 Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy. 2004 Jan 15 1
12 15886878 The VEGF receptor tyrosine kinase inhibitor, ZD6474, inhibits angiogenesis and affects microvascular architecture within an orthotopically implanted renal cell carcinoma. 2004 1
13 12684431 Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase. 2003 Apr 3