Benzodiazepines

tryptophanyl-tRNA synthetase 1 ; Homo sapiens







14 Article(s)
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Pub. Year
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1 33554986 How does α1Histidine102 affect the binding of modulators to α1β2γ2 GABAA receptors? molecular insights from in silico experiments. 2021 Feb 19 1
2 28445782 The immunohistochemical distribution of the GABAA receptor α1, α2, α3, β2/3 and γ2 subunits in the human thalamus. 2017 Jul 1
3 29138471 α subunits in GABAA receptors are dispensable for GABA and diazepam action. 2017 Nov 14 1
4 26255765 Advances in the pharmacology of lGICs auxiliary subunits. 2015 Nov 1
5 23407108 The benzodiazepine diazepam potentiates responses of α1β2γ2L γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists. 2013 Jun 4
6 23091016 Benzodiazepine treatment induces subtype-specific changes in GABA(A) receptor trafficking and decreases synaptic inhibition. 2012 Nov 6 1
7 20417252 Human locus coeruleus neurons express the GABA(A) receptor gamma2 subunit gene and produce benzodiazepine binding. 2010 Jun 21 1
8 14573876 Recombinant extracellular domain of the three major subunits of GABAA receptor show comparable secondary structure and benzodiazepine binding properties. 2003 Nov 2
9 14597328 Mutations linked to generalized epilepsy in humans reduce GABA(A) receptor current. 2003 Nov 1
10 12171574 Mapping of the benzodiazepine recognition site on GABA(A) receptors. 2002 Aug 1
11 10871693 Role of the GABA(A)beta2, GABA(A)alpha6, GABA(A)alpha1 and GABA(A)gamma2 receptor subunit genes cluster in drug responses and the development of alcohol dependence. 2000 Nov-Dec 1
12 9238062 A point mutation in the gamma2 subunit of gamma-aminobutyric acid type A receptors results in altered benzodiazepine binding site specificity. 1997 Aug 5 1
13 9014159 The gamma 2 subunit of the GABAA receptor is concentrated in synaptic junctions containing the alpha 1 and beta 2/3 subunits in hippocampus, cerebellum and globus pallidus. 1996 1
14 1321425 Human chromosomal localization of genes encoding the gamma 1 and gamma 2 subunits of the gamma-aminobutyric acid receptor indicates that members of this gene family are often clustered in the genome. 1992 Jul 1 1