olaparib

poly(ADP-ribose) polymerase 2 ; Homo sapiens







12 Article(s)
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1 35349716 PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites. 2022 Apr 22 2
2 35430559 Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancer. 2022 Jun 5 1
3 33637776 BKM120 sensitizes BRCA-proficient triple negative breast cancer cells to olaparib through regulating FOXM1 and Exo1 expression. 2021 Feb 26 1
4 34461785 Three-component Castagnoli-Cushman reaction with ammonium acetate delivers 2-unsubstituted isoquinol-1-ones as potent inhibitors of poly(ADP-ribose) polymerase (PARP). 2021 Dec 1
5 34880209 FDI-6 inhibits the expression and function of FOXM1 to sensitize BRCA-proficient triple-negative breast cancer cells to Olaparib by regulating cell cycle progression and DNA damage repair. 2021 Dec 8 2
6 32221289 Differential regulation of breast cancer bone metastasis by PARP1 and PARP2. 2020 Mar 27 2
7 30116283 Advances in the use of PARP inhibitor therapy for breast cancer. 2018 1
8 29262611 PARP inhibition causes premature loss of cohesion in cancer cells. 2017 Nov 28 6
9 26931795 New Targeted Agents in Gynecologic Cancers: Synthetic Lethality, Homologous Recombination Deficiency, and PARP Inhibitors. 2016 Mar 1
10 25757679 Olaparib: an oral PARP-1 and PARP-2 inhibitor with promising activity in ovarian cancer. 2015 4
11 22524618 The combination of olaparib and camptothecin for effective radiosensitization. 2012 Apr 23 1
12 18800822 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1. 2008 Oct 23 1