| 1 |
19185518 | A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells. | 2009 Feb 20 |
1 |
| 2 |
19586919 | Inhibition and activation by CD244 depends on CD2 and phospholipase C-gamma1. | 2009 Sep 11 |
1 |
| 3 |
17234744 | Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2- versus IL-15-activated NK cells. | 2007 May 1 |
1 |
| 4 |
15240680 | Adenosine acts through A2 receptors to inhibit IL-2-induced tyrosine phosphorylation of STAT5 in T lymphocytes: role of cyclic adenosine 3',5'-monophosphate and phosphatases. | 2004 Jul 15 |
4 |
| 5 |
12637316 | IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells. | 2003 Jul 1 |
2 |
| 6 |
11815609 | Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain. | 2002 Apr 5 |
1 |
| 7 |
11909529 | The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3. | 2002 Mar 19 |
1 |
| 8 |
11278301 | Ultraviolet radiation inhibits interleukin-2-induced tyrosine phosphorylation and the activation of STAT5 in T lymphocytes. | 2001 Apr 20 |
3 |
| 9 |
10861847 | Mercuric chloride stimulates distinct signal transduction pathway for DNA synthesis in a T-cell line, CTLL-2. | 2000 Jun 6 |
1 |
| 10 |
10898499 | Co-stimulation of IL-2 production by CD28 is independent of tyrosine-based signaling motifs in a murine T cell hybridoma. | 2000 Jun |
1 |
| 11 |
10499915 | Cytotoxic T lymphocyte antigen 4 (CTLA-4) engagement delivers an inhibitory signal through the membrane-proximal region in the absence of the tyrosine motif in the cytoplasmic tail. | 1999 Sep 20 |
1 |
| 12 |
9079703 | Interleukin-2 (IL-2)-mediated induction of the IL-2 receptor alpha chain gene. Critical role of two functionally redundant tyrosine residues in the IL-2 receptor beta chain cytoplasmic domain and suggestion that these residues mediate more than Stat5 activation. | 1997 Mar 28 |
6 |
| 13 |
9200434 | The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms. | 1997 Jul 1 |
2 |
| 14 |
9578412 | Role of interleukin (IL)-2 and IL-15 in the tumour progression of a melanoma cell line MELP, derived from an IL-2 progressor patient. | 1997 Aug |
1 |
| 15 |
8643566 | Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling. | 1996 May 28 |
2 |
| 16 |
8671684 | Demonstration of a cross-talk between IL-2 and IL-5 in phosphorylation of IL-2 and IL-5 receptor beta chains. | 1996 Jun |
2 |
| 17 |
8977326 | The role of tyrosine phosphorylation and PTP-1C in CTLA-4 signal transduction. | 1996 Dec |
1 |
| 18 |
9384701 | Gene therapy with modified tumor cells enables T-cell activation by stimulating pathways required for signal transduction. | 1996 Sep |
2 |
| 19 |
7489734 | Differences in the interleukin-2 (IL-2) receptor system in human and mouse: alpha chain is required for formation of the functional mouse IL-2 receptor. | 1995 Nov |
3 |
| 20 |
7499411 | Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association. | 1995 Dec 1 |
1 |
| 21 |
7543676 | Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. | 1995 Aug 1 |
1 |
| 22 |
7593241 | Regulation of apoptosis of interleukin 2-dependent mouse T-cell line by protein tyrosine phosphorylation and polyamines. | 1995 Dec |
1 |
| 23 |
7744803 | Protein-tyrosine kinase-dependent activation of STAT transcription factors in interleukin-2- or interleukin-4-stimulated T lymphocytes. | 1995 May 12 |
1 |
| 24 |
7759480 | Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide. | 1995 May 26 |
1 |
| 25 |
7781605 | Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways. | 1995 Jun 1 |
2 |
| 26 |
7515100 | The Src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line. | 1994 Jun 1 |
3 |
| 27 |
8088325 | Gene transfer of the interleukin (IL)-2 receptor beta chain into an IL-7-dependent pre-B cell line permits IL-2-driven proliferation: tyrosine phosphorylation of Shc is induced by IL-2 but not IL-7. | 1994 Sep |
1 |
| 28 |
8207200 | Signal transduction mediated by the reconstituted IL-2 receptor. Evidence for a cell type-specific function of IL-2 receptor beta-chain. | 1994 Jun 15 |
1 |
| 29 |
8294403 | The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation. | 1994 Jan 21 |
4 |
| 30 |
7682694 | Murine T-lymphocyte proliferation induced by interleukin 2 correlates with a transient increase in p56lck kinase activity and the tyrosine phosphorylation of a 97-kDa protein. | 1993 Apr 15 |
3 |
| 31 |
7685905 | Interleukin 2 regulates Raf-1 kinase activity through a tyrosine phosphorylation-dependent mechanism in a T-cell line. | 1993 Jun 15 |
5 |
| 32 |
7686931 | Altered protein tyrosine phosphorylation in anergic Th1 cells. | 1993 Jul 1 |
1 |
| 33 |
8103063 | Reduced CD3-mediated protein tyrosine phosphorylation in anergic CD4+ and CD8+ T cells. | 1993 Sep 1 |
2 |
| 34 |
8483935 | Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction. | 1993 May 1 |
2 |
| 35 |
1357030 | Anergic Th1 cells express altered levels of the protein tyrosine kinases p56lck and p59fyn. | 1992 Nov 1 |
1 |
| 36 |
1384486 | Interleukin-2 (IL-2) induces erythroid differentiation and tyrosine phosphorylation in ELM-I-1 cells transfected with a human IL-2 receptor beta chain cDNA. | 1992 Oct 15 |
2 |
| 37 |
1467516 | Activation of the erythropoietin receptor by the Friend spleen focus-forming virus gp55 glycoprotein induces constitutive protein tyrosine phosphorylation. | 1992 Dec 15 |
1 |
| 38 |
1652056 | Interleukin 2- and polyomavirus middle T antigen-induced modification of phosphatidylinositol 3-kinase activity in activated T lymphocytes. | 1991 Sep |
2 |
| 39 |
1655887 | IL-2 binding activates a tyrosine-phosphorylated phosphatidylinositol-3-kinase. | 1991 Oct 1 |
2 |
| 40 |
1713578 | Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase. | 1991 Aug 5 |
1 |
| 41 |
1850360 | Interleukin 2 stimulates serine phosphorylation of CD45 in CTLL-2.4 cells. | 1991 Apr |
3 |
| 42 |
1996324 | Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line. | 1991 Feb 15 |
2 |
| 43 |
2007186 | Ligand-stimulated tyrosine phosphorylation of the IL-2 receptor beta chain and receptor-associated proteins. | 1991 Jan |
4 |
| 44 |
1690713 | Protein tyrosine phosphorylation associated with activation of the interleukin 2 receptor. | 1990 Apr 5 |
4 |
| 45 |
1697878 | Tyrosine phosphorylation is an obligatory event in IL-2 secretion. | 1990 Oct 1 |
2 |
| 46 |
2334739 | Differential effects of interleukin-2 and interleukin-4 on protein tyrosine phosphorylation in factor-dependent murine T cells. | 1990 May 2 |
4 |
| 47 |
3259228 | Activation of a tyrosine protein kinase is an early event in the stimulation of T lymphocytes by interleukin-2. | 1988 May 25 |
4 |
| 48 |
3260330 | Hematopoietic growth factors activate the tyrosine phosphorylation of distinct sets of proteins in interleukin-3-dependent murine cell lines. | 1988 May |
1 |