Tretinoin

cytochrome P450 family 26 subfamily A member 1 ; Homo sapiens







145 Article(s)
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101 16933217 Evidence for a functional genetic polymorphism of the human retinoic acid-metabolizing enzyme CYP26A1, an enzyme that may be involved in spina bifida. 2006 Jun 3
102 17059167 Homology model of human retinoic acid metabolising enzyme cytochrome P450 26A1 (CYP26A1): active site architecture and ligand binding. 2006 Aug 2
103 15589975 Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides. 2005 Jan 1 4
104 15703382 Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death. 2005 May 2
105 15714209 Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells. 2005 Feb 28 2
106 15745819 Potent and selective [2-imidazol-1-yl-2-(6-alkoxy-naphthalen-2-yl)-1-methyl-ethyl]-dimethyl-amines as retinoic acid metabolic blocking agents (RAMBAs). 2005 Mar 15 1
107 15896339 Regulation of CYP26A1 expression by selective RAR and RXR agonists in human NB4 promyelocytic leukemia cells. 2005 Jun 1 5
108 16143075 [Study on the synergic effect of all-trans retinoic acid combined with IFN-alpha on the proliferation and differentiation of HL-60 cells]. 2005 Sep 1
109 16194896 Regulation of a highly specific retinoic acid-4-hydroxylase (CYP26A1) enzyme and all-trans-retinoic acid metabolism in human intestinal, liver, endothelial, and acute promyelocytic leukemia cells. 2005 Oct 12
110 16279770 Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays. 2005 Nov 17 1
111 14532297 A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid. 2004 Jan 2 3
112 14704332 Regulation of hepatic retinol metabolism: perspectives from studies on vitamin A status. 2004 Jan 2
113 15281009 The effect of cellular retinoic acid binding protein-I expression on the CYP26-mediated catabolism of all-trans retinoic acid and cell proliferation in head and neck squamous cell carcinoma. 2004 Aug 1
114 15291358 Nuclear retinoid receptors are involved in N-(4-hydroxyphenyl) retinamide (Fenretinide)-induced gene expression and growth inhibition in HL-60 acute myeloid leukemia cells. 2004 May 2
115 15451545 Delivery of all trans-retinoic acid (RA) to hepatocyte cell line from RA/galactosyl alpha-cyclodextrin inclusion complex. 2004 Nov 1
116 12711469 Cutaneous expression of cytochrome P450 CYP2S1: individuality in regulation by therapeutic agents for psoriasis and other skin diseases. 2003 Apr 19 2
117 12870655 Transcript profiling of cytochrome P450 genes in HL-60 human leukemic cells: upregulation of CYP1B1 by all-trans-retinoic acid. 2003 Jun 1
118 11912557 Retinoic acid 4-hydroxylase-mediated catabolism of all-trans retinoic acid and the cell proliferation in head and neck squamous cell carcinoma. 2002 Apr 8
119 11953746 Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development. 2002 May 2
120 11994980 all-trans-Retinoic acid-induced expression and regulation of retinoic acid 4-hydroxylase (CYP26) in human promyelocytic leukemia. 2002 May 10
121 12054474 Cloning of rat cytochrome P450RAI (CYP26) cDNA and regulation of its gene expression by all-trans-retinoic acid in vivo. 2002 May 15 5
122 11302942 Effects of receptor-selective retinoids on CYP26 gene expression and metabolism of all-trans-retinoic acid in intestinal cells. 2001 May 1
123 11309353 Enhanced turnover of all-trans-retinoic acid and increased formation of polar metabolites in head and neck squamous cell carcinoma lines compared with normal oral keratinocytes. 2001 Apr 3
124 11471143 Differential expression of chicken CYP26 in anterior versus posterior limb bud in response to retinoic acid. 2001 Jul 1 2
125 11522124 Roles of cytochrome p450 in development. 2001 1
126 11606945 Retinoic acid metabolism. 2001 Nov 1
127 11690641 Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells. 2001 Oct 31 1
128 11766909 Retinoic acid homeostasis: retinoic acid regulates liver retinol esterification as well as its own catabolic oxidation in liver. 2001 Dec 3
129 10702251 4-hydroxyretinoic acid, a novel substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. 2000 Mar 10 1
130 10727725 Patterns of CYP26 expression in human prenatal cephalic and hepatic tissues indicate an important role during early brain development. 2000 Mar 15 3
131 10862743 Regulation of retinoic acid signaling during lung morphogenesis. 2000 Jul 1
132 10953040 Induction of the cytochrome P450 gene CYP26 during mucous cell differentiation of normal human tracheobronchial epithelial cells. 2000 Sep 2
133 11023996 Regulation of CYP26 (cytochrome P450RAI) mRNA expression and retinoic acid metabolism by retinoids and dietary vitamin A in liver of mice and rats. 2000 Oct 1
134 11025452 Retinol conversion to retinoic acid is impaired in breast cancer cell lines relative to normal cells. 2000 Nov 6
135 11082432 Metabolism of vitamin A and its active metabolite all-trans-retinoic acid in small intestinal enterocytes. 2000 Dec 2
136 10421060 The vitamin A metabolism and expression of retinoid-binding proteins differ in HaCaT cells and normal human keratinocytes. 1999 Jun 1
137 10479456 Retinoic acid hydroxylase (CYP26) is a key enzyme in neuronal differentiation of embryonal carcinoma cells. 1999 Sep 15 1
138 10540859 [Basic aspects of vitamin A--chemical structure, physiological functions and metabolism]. 1999 Oct 1
139 9564181 The cloning and characterization of a novel cytochrome P450 family, CYP26, with specificity toward retinoic acid. 1998 Mar 2
140 9716180 Human retinoic acid (RA) 4-hydroxylase (CYP26) is highly specific for all-trans-RA and can be induced through RA receptors in human breast and colon carcinoma cells. 1998 Aug 7
141 9857269 Metabolism of retinoic acid: implications for development and cancer. 1998 1
142 9228017 cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450. 1997 Jul 25 6
143 9228041 CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family. 1997 Jul 25 1
144 8601734 Retinoic acid isomers applied to human skin in vivo each induce a 4-hydroxylase that inactivates only trans retinoic acid. 1996 Feb 1
145 8757760 Liarozole inhibits human epidermal retinoic acid 4-hydroxylase activity and differentially augments human skin responses to retinoic acid and retinol in vivo. 1996 Aug 1