Morphine

opioid receptor mu 1 ; Homo sapiens







242 Article(s)
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1 34256067 Experimental considerations for the assessment of in vivo and in vitro opioid pharmacology. 2022 Feb 1
2 35565382 Chronic Cancer Pain: Opioids within Tumor Microenvironment Affect Neuroinflammation, Tumor and Pain Evolution. 2022 Apr 30 1
3 35609510 Effects of the mu-opioid receptor agonist morphine on facial mimicry and emotion recognition. 2022 Aug 2
4 31413370 Morphine coordinates SST and PV interneurons in the prelimbic cortex to disinhibit pyramidal neurons and enhance reward. 2021 Apr 3
5 32800527 A118G polymorphism of OPRM1 gene caused different morphine consumption in female patients after total knee replacement. 2021 Jul 4
6 33184860 Morphine promotes tumorigenesis and cetuximab resistance via EGFR signaling activation in human colorectal cancer. 2021 Jun 4
7 33373630 Ligand based conformational space studies of the μ-opioid receptor. 2021 Mar 3
8 33384303 Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for μ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats. 2021 Mar 1
9 33444617 Probing biased activation of mu-opioid receptor by the biased agonist PZM21 using all atom molecular dynamics simulation. 2021 Mar 15 2
10 33448226 Structural Assessment of Agonist Efficacy in the μ-Opioid Receptor: Morphine and Fentanyl Elicit Different Activation Patterns. 2021 Mar 22 2
11 33624141 μ-Opioid Receptor-Mediated Enteric Glial Activation Is Involved in Morphine-Induced Constipation. 2021 Jul 2
12 33790790 The Balance of MU-Opioid, Dopamine D2 and Adenosine A2A Heteroreceptor Complexes in the Ventral Striatal-Pallidal GABA Antireward Neurons May Have a Significant Role in Morphine and Cocaine Use Disorders. 2021 12
13 33847389 Pharmacogenomics and Morphine. 2021 Sep 1
14 34002697 ß-arrestin 2 germline knockout does not attenuate opioid respiratory depression. 2021 May 18 2
15 34015137 Innate Immune and Neuronal Genetic Markers Are Highly Predictive of Postoperative Pain and Morphine Patient-Controlled Analgesia Requirements in Indian but Not Chinese or Malay Hysterectomy Patients. 2021 Nov 26 1
16 34420144 Modulation of OPRM1 Alternative Splicing by Morphine and HIV-1 Nef. 2021 Aug 21 5
17 34523422 Reviewing pharmacogenetics to advance precision medicine for opioids. 2021 Oct 1
18 34642456 CRHCeA→VTA inputs inhibit the positive ensembles to induce negative effect of opiate withdrawal. 2021 Nov 2
19 34689504 The Influence of OPRM1 A118G Polymorphism on the Dosage of Morphine in Patients with Advanced Liver Cancer. 2021 Nov 4
20 31596498 Opioids differentially modulate two synapses important for pain processing in the amygdala. 2020 Jan 1
21 31790782 Post-trial low dose apomorphine prevents the development of morphine sensitization. 2020 Feb 17 1
22 31958407 Confronting the opioid crisis with basic research in neuropharmacology. 2020 Apr 2
23 31999011 Morphine modulates the expression of mu-opioid receptor exon 5-associated full-length C-terminal splice variants by upregulating miR-378a-3p. 2020 Mar 1
24 32040076 Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu-opioid receptor splice variants. 2020 Jun 1
25 32179045 Assessment of structure-activity relationships and biased agonism at the Mu opioid receptor of novel synthetic opioids using a novel, stable bio-assay platform. 2020 Jul 2
26 32320702 DAMGO-induced μ opioid receptor internalization and recycling restore morphine sensitivity in tolerant rat. 2020 Jul 5 2
27 32344154 HIV and opiates dysregulate K+- Cl- cotransporter 2 (KCC2) to cause GABAergic dysfunction in primary human neurons and Tat-transgenic mice. 2020 Jul 1
28 32362586 Chronic Treatment with Morphine Disrupts Acute Kinase-Dependent Desensitization of GPCRs. 2020 Oct 2
29 32442101 Pharmacogenetics of Postoperative Pain Management: A Review. 2020 Jun 1
30 32497566 The search for opioid analgesics with limited tolerance liability. 2020 Aug 2
31 32513839 Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters. 2020 Sep 2
32 32630190 Molecular Dynamics Simulations to Investigate How PZM21 Affects the Conformational State of the μ-Opioid Receptor Upon Activation. 2020 Jul 1 1
33 32680919 Atomic-Level Characterization of the Methadone-Stabilized Active Conformation of µ-Opioid Receptor. 2020 Oct 1
34 33091380 Affinity, potency, efficacy, selectivity, and molecular modeling of substituted fentanyls at opioid receptors. 2020 Dec 1
35 33185388 Resistin Gene Polymorphism Is an Influencing Factor of Postoperative Pain for Chinese Patients. 2020 Nov 1
36 30166422 The effect of acute morphine on obstructive sleep apnoea: a randomised double-blind placebo-controlled crossover trial. 2019 Feb 1
37 30391425 Determinants of opioid abuse potential: Insights using intracranial self-stimulation. 2019 Feb 2
38 30592275 Pain polymorphisms and opioids: An evidence based review. 2019 Mar 2
39 30682345 Pharmacological activation of dopamine D4 receptor modulates morphine-induced changes in the expression of GAD65/67 and GABAB receptors in the basal ganglia. 2019 Jul 1 5
40 30915986 The mu-opioid receptor is a molecular marker for poor prognosis in hepatocellular carcinoma and represents a potential therapeutic target. 2019 Jun 1
41 30945497 [Electroacupuncture intervention relieves pain possibly by promoting MOR endocytosis in locus coeruleus in bone cancer pain rats with morphine tolerance]. 2019 Mar 25 1
42 31243060 Identification of Abundant and Evolutionarily Conserved Opioid Receptor Circular RNAs in the Nervous System Modulated by Morphine. 2019 Aug 2
43 31316354 Neuropathic Pain Induced Alterations in the Opioidergic Modulation of a Descending Pain Facilitatory Area of the Brain. 2019 2
44 31515267 Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks. 2019 Nov 1 5
45 31717871 Discovery of Novel µ-Opioid Receptor Inverse Agonist from a Combinatorial Library of Tetrapeptides through Structure-Based Virtual Screening. 2019 Oct 27 1
46 31743739 Pharmacological characterization of 17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-[(3'-fluoro-4'-pyridyl)acetamido]morphinan (NFP) as a dual selective MOR/KOR ligand with potential applications in treating opioid use disorder. 2019 Dec 15 1
47 32116679 Desmetramadol Is Identified as a G-Protein Biased µ Opioid Receptor Agonist. 2019 1
48 28591085 Influence of OPRM1 Polymorphism on Postoperative Pain After Intrathecal Morphine Administration in Italian Patients Undergoing Elective Cesarean Section. 2018 Feb 2
49 29344928 Morphine-Mediated Brain Region-Specific Astrocytosis Involves the ER Stress-Autophagy Axis. 2018 Aug 3
50 29716811 Neuropeptide oxytocin enhances μ opioid receptor signaling as a positive allosteric modulator. 2018 May 1