Tetradecanoylphorbol Acetate

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Raf-1 proto-oncogene, serine/threonine kinase ; Homo sapiens







39 Article(s)
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1 30513386 c-Raf participates in adaptive immune response of Nile tilapia via regulating lymphocyte activation. 2019 Mar 1
2 17976640 Regulation of mTOR and S6K1 activation by the nPKC isoforms, PKCepsilon and PKCdelta, in adult cardiac muscle cells. 2007 Dec 1
3 16504566 Methylglyoxal downregulates Raf-1 protein through a ubiquitination-mediated mechanism. 2006 2
4 15567061 Phorbol 12-myristate 13-acetate upregulates cyclooxygenase-2 expression in human pulmonary epithelial cells via Ras, Raf-1, ERK, and NF-kappaB, but not p38 MAPK, pathways. 2005 Mar 4
5 12536201 RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines. 2003 Feb 1
6 12551925 Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. 2003 Apr 11 1
7 12801911 Regulation of ERK-mediated signal transduction by p38 MAP kinase in human monocytic THP-1 cells. 2003 May 2
8 11940578 c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells. 2002 Jun 21 2
9 11956220 Activation of human monoamine oxidase B gene expression by a protein kinase C MAPK signal transduction pathway involves c-Jun and Egr-1. 2002 Jun 21 1
10 12054499 FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway. 2002 May 17 1
11 11257453 Activation of Ras, Raf-1 and protein kinase C in differentiating human neuroblastoma cells after treatment with phorbolester and NGF. 2001 Feb 3
12 11719466 Induction of glucose-regulated protein 78 by chronic hypoxia in human gastric tumor cells through a protein kinase C-epsilon/ERK/AP-1 signaling cascade. 2001 Nov 15 1
13 10825394 Bryostatin 1 induces prolonged activation of extracellular regulated protein kinases in and apoptosis of LNCaP human prostate cancer cells overexpressing protein kinase calpha. 2000 Jun 1
14 10871841 Annexin V inhibits the 12-O-tetradecanoylphorbol-13-acetate-induced activation of Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of Shc in MCF-7 cells. 2000 Jun 8 2
15 10926560 Role of ras-dependent ERK activation in phorbol ester-induced endothelial cell barrier dysfunction. 2000 Aug 1
16 10400418 Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells. 1999 Jul 1
17 10523856 Phorbol ester induced MDR1 expression in K562 cells occurs independently of mitogen-activated protein kinase signaling pathways. 1999 Oct 14 3
18 9632690 Mutations in the hydrophobic surface of an amphipathic groove of 14-3-3zeta disrupt its interaction with Raf-1 kinase. 1998 Jun 26 1
19 9794231 Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms. 1998 Sep 24 2
20 9067628 Activation of Raf-1 and mitogen-activated protein kinases by erythropoietin and inositolphosphate-glycan in normal erythroid progenitor cells: involvement of protein kinase C. 1997 Jan 1
21 9392422 Phorbol ester-induced low density lipoprotein receptor gene expression in HepG2 cells involves protein kinase C-mediated p42/44 MAP kinase activation. 1997 Nov 1
22 8621441 The seven-transmembrane-spanning receptors for endothelin and thrombin cause proliferation of airway smooth muscle cells and activation of the extracellular regulated kinase and c-Jun NH2-terminal kinase groups of mitogen-activated protein kinases. 1996 Mar 8 3
23 8642652 Raf-1 kinase targets GA-binding protein in transcriptional regulation of the human immunodeficiency virus type 1 promoter. 1996 Apr 2
24 8662746 A role for Shc, Grb2, and Raf-1 in FcgammaRI signal relay. 1996 Jun 7 1
25 7478524 Phorbol ester-resistant monoblastoid leukemia cells with a functional mitogen-activated protein kinase cascade but without responsive protein tyrosine phosphatases. 1995 Nov 16 1
26 7534298 The MEK kinase activity of the catalytic domain of RAF-1 is regulated independently of Ras binding in T cells. 1995 Mar 10 1
27 7588214 Forskolin inhibits protein kinase C-induced mitogen activated protein kinase activity in MC3T3-E1 osteoblasts. 1995 Nov 1
28 7717978 The membrane immunoglobulin receptor utilizes a Shc/Grb2/hSOS complex for activation of the mitogen-activated protein kinase cascade in a B-cell line. 1995 Apr 1 2
29 7799956 Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macrophages. 1995 Jan 1
30 7516337 The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase. Evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant. 1994 Jun 24 1
31 7929360 Tumor necrosis factor alpha stimulates AP-1 activity through prolonged activation of the c-Jun kinase. 1994 Oct 21 2
32 7935389 Mechanism of inhibition of Raf-1 by protein kinase A. 1994 Oct 1
33 7936644 Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK: reconstitution of the signalling pathway in vitro. 1994 Nov 2
34 8125975 Cross-linking of surface IgM stimulates the Ras/Raf-1/MEK/MAPK cascade in human B lymphocytes. 1994 Mar 11 2
35 8195229 Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation. 1994 Jun 3 2
36 8288641 Activation of Raf-1 and mitogen-activated protein kinases during monocytic differentiation of human myeloid leukemia cells. 1994 Jan 14 3
37 8223446 Raf-1 is required for T cell IL2 production. 1993 Nov 2
38 1437148 Activation of the c-Raf protein kinase by protein kinase C phosphorylation. 1992 Nov 6
39 1845931 Granulocyte-macrophage colony-stimulating factor and interleukin-3 induce rapid phosphorylation and activation of the proto-oncogene Raf-1 in a human factor-dependent myeloid cell line. 1991 Jan 15 1