Chlorides

solute carrier family 12 member 5 ; Homo sapiens







101 Article(s)
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Pub. Year
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1 34883135 CNS pharmacology of NKCC1 inhibitors. 2022 Mar 1 1
2 35159205 The GABA Polarity Shift and Bumetanide Treatment: Making Sense Requires Unbiased and Undogmatic Analysis. 2022 Jan 24 1
3 35448033 NKCC1 Deficiency in Forming Hippocampal Circuits Triggers Neurodevelopmental Disorder: Role of BDNF-TrkB Signalling. 2022 Apr 15 1
4 33239270 KCC2 Chloride Transport Contributes to the Termination of Ictal Epileptiform Activity. 2021 Mar-Apr 7
5 33640193 The Multifaceted Roles of KCC2 in Cortical Development. 2021 May 1
6 34620512 Pharmacological tools to target NKCC1 in brain disorders. 2021 Dec 1
7 34707084 Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission. 2021 Oct 27 2
8 34849164 Role of the cation-chloride-cotransporters in the circadian system. 2021 Sep 1
9 34858138 WNK3 Maintains the GABAergic Inhibitory Tone, Synaptic Excitation and Neuronal Excitability via Regulation of KCC2 Cotransporter in Mature Neurons. 2021 1
10 34955901 Contribution of Smoothened Receptor Signaling in GABAergic Neurotransmission and Chloride Homeostasis in the Developing Rodent Brain. 2021 1
11 30871970 KCC2 membrane diffusion tunes neuronal chloride homeostasis. 2020 Jun 1 2
12 31826658 KCC2 Much Chloride Might Not Be the Only Problem. 2020 Jan-Feb 1
13 31930378 GABA in, garbage out: AIS-located proteasomes regulate the developmental GABA switch. 2020 Feb 3 1
14 32064760 Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons. 2020 Apr 3 2
15 32078115 Caffeine exposure ameliorates acute ischemic cell death in avian developing retina. 2020 Mar 1
16 32322187 Chloride - The Underrated Ion in Nociceptors. 2020 2
17 32359429 Nest Carbon Dioxide Masks GABA-Dependent Seizure Susceptibility in the Naked Mole-Rat. 2020 Jun 8 1
18 32769979 Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization. 2020 Aug 7 2
19 32892950 Coordinated downregulation of KCC2 and GABAA receptor contributes to inhibitory dysfunction during seizure induction. 2020 Nov 12 1
20 33266310 The Therapeutic Potential of Neuronal K-Cl Co-Transporter KCC2 in Huntington's Disease and Its Comorbidities. 2020 Nov 30 2
21 30417726 Furosemide Unmasks Inhibitory Dysfunction after Spinal Cord Injury in Humans: Implications for Spasticity. 2019 May 1 1
22 30590202 Cervical spinal contusion alters Na+-K+-2Cl- and K+-Cl- cation-chloride cotransporter expression in phrenic motor neurons. 2019 Mar 2
23 30784026 A Preliminary Study Evaluating the Safety and Efficacy of Bumetanide, an NKCC1 Inhibitor, in Patients with Drug-Resistant Epilepsy. 2019 Mar 1
24 31174368 Amyloid Precursor Protein (APP) and GABAergic Neurotransmission. 2019 Jun 6 1
25 31315039 Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes. 2019 Jul 16 4
26 31803025 Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation. 2019 2
27 31806759 5-HT2A receptor activation normalizes stress-induced dysregulation of GABAergic signaling in the ventral tegmental area. 2019 Dec 5 2
28 32010056 Role of NKCC1 and KCC2 in Epilepsy: From Expression to Function. 2019 2
29 28677029 The Role of K+-Cl--Cotransporter-2 in Neuropathic Pain. 2018 Jan 4
30 29218745 Expression of the potassium-chloride co-transporter, KCC2, within the avian song system. 2018 Apr 15 1
31 29729285 Chloride transporters and GABA polarity in developmental, neurological and psychiatric conditions. 2018 Jul 1
32 29782876 Chloride cotransporter KCC2 is essential for GABAergic inhibition in the SCN. 2018 Aug 1
33 30169756 KCC2 Regulates Dendritic Spine Formation in a Brain-Region Specific and BDNF Dependent Manner. 2018 Nov 1 1
34 30406192 Role of the K+-Cl- Cotransporter KCC2a Isoform in Mammalian Respiration at Birth. 2018 Sep-Oct 1
35 28057537 The chloride co-transporters, NKCC1 and KCC2, in experimental autoimmune encephalomyelitis (EAE). 2017 Mar 6 2
36 28333147 Solute carrier family 12 member 5 promotes tumor invasion/metastasis of bladder urothelial carcinoma by enhancing NF-κB/MMP-7 signaling pathway. 2017 Mar 23 2
37 28450542 Neuronal Chloride Regulation via KCC2 Is Modulated through a GABAB Receptor Protein Complex. 2017 May 31 5
38 28803659 Seizing Control of KCC2: A New Therapeutic Target for Epilepsy. 2017 Sep 1
39 28888841 Implications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function. 2017 Nov 15 1
40 29176664 GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase. 2017 Nov 24 2
41 29184062 Molecular architecture of potassium chloride co-transporter KCC2. 2017 Nov 28 1
42 26427846 Enhanced expression of potassium-chloride cotransporter KCC2 in human temporal lobe epilepsy. 2016 Sep 2
43 26506510 Nonsynaptic glycine release is involved in the early KCC2 expression. 2016 Jul 1
44 26780567 KCC2 knockdown impairs glycinergic synapse maturation in cultured spinal cord neurons. 2016 Jun 1
45 27002180 GABAA receptor-mediated neurotransmission: Not so simple after all. 2016 Sep 1 1
46 27513374 Compromised GABAergic inhibition contributes to tumor-associated epilepsy. 2016 Oct 1
47 27852771 Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model. 2016 Nov 16 4
48 27881775 A Biophysical Model for Cytotoxic Cell Swelling. 2016 Nov 23 1
49 29143559 K+-Cl- co-transporter 2 (KCC2) - a membrane trafficking perspective. 2016 Sep - Dec 1
50 24909111 K-Cl cotransporter KCC2--a moonlighting protein in excitatory and inhibitory synapse development and function. 2015 Apr 1