| 1 |
34528073 | Inhibiting with-no-lysine kinases enhances K+/Cl- cotransporter 2 activity and limits status epilepticus. | 2022 Apr 29 |
4 |
| 2 |
35352582 | KCC2 receptor upregulation potentiates antinociceptive effect of GABAAR agonist on remifentanil-induced hyperalgesia. | 2022 Jan-Dec |
3 |
| 3 |
35448033 | NKCC1 Deficiency in Forming Hippocampal Circuits Triggers Neurodevelopmental Disorder: Role of BDNF-TrkB Signalling. | 2022 Apr 15 |
2 |
| 4 |
33539918 | KCC2 is required for the survival of mature neurons but not for their development. | 2021 Jan-Jun |
2 |
| 5 |
34500023 | Developmental dysregulation of excitatory-to-inhibitory GABA-polarity switch may underlie schizophrenia pathology: A monozygotic-twin discordant case analysis in human iPS cell-derived neurons. | 2021 Nov |
1 |
| 6 |
34707084 | Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission. | 2021 Oct 27 |
1 |
| 7 |
34858138 | WNK3 Maintains the GABAergic Inhibitory Tone, Synaptic Excitation and Neuronal Excitability via Regulation of KCC2 Cotransporter in Mature Neurons. | 2021 |
1 |
| 8 |
35095429 | Striatal Chloride Dysregulation and Impaired GABAergic Signaling Due to Cation-Chloride Cotransporter Dysfunction in Huntington's Disease. | 2021 |
2 |
| 9 |
31930378 | GABA in, garbage out: AIS-located proteasomes regulate the developmental GABA switch. | 2020 Feb 3 |
1 |
| 10 |
33060559 | Environmental regulation of the chloride transporter KCC2: switching inflammation off to switch the GABA on? | 2020 Oct 15 |
2 |
| 11 |
30417726 | Furosemide Unmasks Inhibitory Dysfunction after Spinal Cord Injury in Humans: Implications for Spasticity. | 2019 May 1 |
1 |
| 12 |
30576625 | Pathogenic potential of human SLC12A5 variants causing KCC2 dysfunction. | 2019 May 1 |
6 |
| 13 |
30977423 | The etiological contribution of GABAergic plasticity to the pathogenesis of neuropathic pain. | 2019 Jan-Dec |
1 |
| 14 |
31803025 | Identification of KCC2 Mutations in Human Epilepsy Suggests Strategies for Therapeutic Transporter Modulation. | 2019 |
1 |
| 15 |
28057537 | The chloride co-transporters, NKCC1 and KCC2, in experimental autoimmune encephalomyelitis (EAE). | 2017 Mar 6 |
2 |
| 16 |
28888841 | Implications of the N-terminal heterogeneity for the neuronal K-Cl cotransporter KCC2 function. | 2017 Nov 15 |
2 |
| 17 |
26510764 | Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target. | 2016 Jan 1 |
2 |
| 18 |
26733678 | KCC2 rescues functional deficits in human neurons derived from patients with Rett syndrome. | 2016 Jan 19 |
1 |
| 19 |
26780567 | KCC2 knockdown impairs glycinergic synapse maturation in cultured spinal cord neurons. | 2016 Jun |
1 |
| 20 |
27130838 | The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition. | 2016 Dec |
1 |
| 21 |
27180051 | Altered expression of KCC2 in GABAergic interneuron contributes prenatal stress-induced epileptic spasms in infant rat. | 2016 Jul |
1 |
| 22 |
27211329 | Carbonic anhydrase inhibition and the management of neuropathic pain. | 2016 Aug |
1 |
| 23 |
27277799 | BDNF Signaling Promotes Vestibular Compensation by Increasing Neurogenesis and Remodeling the Expression of Potassium-Chloride Cotransporter KCC2 and GABAA Receptor in the Vestibular Nuclei. | 2016 Jun 8 |
1 |
| 24 |
27720487 | Stress Increases Ethanol Self-Administration via a Shift toward Excitatory GABA Signaling in the Ventral Tegmental Area. | 2016 Oct 19 |
1 |
| 25 |
29143559 | K+-Cl- co-transporter 2 (KCC2) - a membrane trafficking perspective. | 2016 Sep - Dec |
4 |
| 26 |
24909111 | K-Cl cotransporter KCC2--a moonlighting protein in excitatory and inhibitory synapse development and function. | 2015 Apr |
2 |
| 27 |
25307426 | Hyperactivation of BDNF-TrkB signaling cascades in human hypothalamic hamartoma (HH): a potential mechanism contributing to epileptogenesis. | 2015 Feb |
2 |
| 28 |
25644702 | An evolutionarily conserved switch in response to GABA affects development and behavior of the locomotor circuit of Caenorhabditis elegans. | 2015 Apr |
1 |
| 29 |
25834055 | Contribution of the potassium-chloride cotransporter KCC2 to the strength of inhibition in the neonatal rodent spinal cord in vitro. | 2015 Apr 1 |
1 |
| 30 |
25878279 | Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain. | 2015 Apr 15 |
1 |
| 31 |
26388734 | Prenatal Hypoxia-Ischemia Induces Abnormalities in CA3 Microstructure, Potassium Chloride Co-Transporter 2 Expression and Inhibitory Tone. | 2015 |
1 |
| 32 |
26441542 | Development and regulation of chloride homeostasis in the central nervous system. | 2015 |
1 |
| 33 |
26528127 | Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia. | 2015 |
3 |
| 34 |
26858607 | Mild KCC2 Hypofunction Causes Inconspicuous Chloride Dysregulation that Degrades Neural Coding. | 2015 |
3 |
| 35 |
24225328 | Seizure-induced disinhibition of the HPA axis increases seizure susceptibility. | 2014 Jan |
1 |
| 36 |
24388924 | Depolarizing chloride gradient in developing cochlear nucleus neurons: underlying mechanism and implication for calcium signaling. | 2014 Mar 7 |
1 |
| 37 |
24615367 | Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain. | 2014 May |
1 |
| 38 |
24835171 | Changes in spinal inhibitory networks induced by furosemide in humans. | 2014 Jul 1 |
1 |
| 39 |
24983520 | Erythropoietin attenuates loss of potassium chloride co-transporters following prenatal brain injury. | 2014 Jul |
1 |
| 40 |
25009229 | Cortical GABAergic excitation contributes to epileptic activities around human glioma. | 2014 Jul 9 |
2 |
| 41 |
25072038 | GABAergic signaling as therapeutic target for autism spectrum disorders. | 2014 |
1 |
| 42 |
25249941 | Metaplasticity and behavior: how training and inflammation affect plastic potential within the spinal cord and recovery after injury. | 2014 |
1 |
| 43 |
25454160 | BDNF-trkB-KCC2-GABA pathway may be related to chronic stress-induced hyperalgesia at both the spinal and supraspinal level. | 2014 Dec |
2 |
| 44 |
23061490 | Bumetanide reduces seizure frequency in patients with temporal lobe epilepsy. | 2013 Jan |
2 |
| 45 |
23341142 | Coupling between GABA-A receptor and chloride transporter underlies ionic plasticity in cerebellar Purkinje neurons. | 2013 Jun |
1 |
| 46 |
23663753 | An unexpected role of neuroligin-2 in regulating KCC2 and GABA functional switch. | 2013 May 12 |
1 |
| 47 |
23964205 | Functional role of ambient GABA in refining neuronal circuits early in postnatal development. | 2013 |
2 |
| 48 |
24139641 | Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2. | 2013 Dec |
1 |
| 49 |
22238092 | GABA is excitatory in adult vasopressinergic neuroendocrine cells. | 2012 Jan 11 |
1 |
| 50 |
22363264 | Role of the neuronal K-Cl co-transporter KCC2 in inhibitory and excitatory neurotransmission. | 2012 |
2 |