Tolcapone

transthyretin ; Homo sapiens







7 Article(s)
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1 35352593 CSF/plasma levels, transthyretin stabilisation and safety of multiple doses of tolcapone in subjects with hereditary ATTR amyloidosis. 2022 Mar 30 4
2 32324953 Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis. 2021 Jan 2
3 32708961 Formulation of Sustained Release Hydrophilic Matrix Tablets of Tolcapone with the Application of Sedem Diagram: Influence of Tolcapone's Particle Size on Sustained Release. 2020 Jul 17 1
4 32791384 Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin. 2020 Oct 6
5 31119947 Transthyretin stabilization activity of the catechol-O-methyltransferase inhibitor tolcapone (SOM0226) in hereditary ATTR amyloidosis patients and asymptomatic carriers: proof-of-concept study. 2019 Jun 9
6 28298647 Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel. 2017 Mar 15 2
7 26902880 Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity. 2016 Feb 23 7