Lactic Acid

hydrocarboxylic acid receptor 1 ; Mus musculus







30 Article(s)
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Pub. Year
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1 35107038 Neuronal GPR81 regulates developmental brain angiogenesis and promotes brain recovery after a hypoxic ischemic insult. 2022 Jul 4
2 33430871 Lactate as a metabolite from probiotic Lactobacilli mitigates ethanol-induced gastric mucosal injury: an in vivo study. 2021 Jan 11 2
3 34093243 Hydroxycarboxylic Acid Receptor 1 and Neuroprotection in a Mouse Model of Cerebral Ischemia-Reperfusion. 2021 3
4 34497346 Microbiota-derived lactate promotes hematopoiesis and erythropoiesis by inducing stem cell factor production from leptin receptor+ niche cells. 2021 Sep 1
5 34588991 The Role of cAMP-PKA Pathway in Lactate-Induced Intramuscular Triglyceride Accumulation and Mitochondria Content Increase in Mice. 2021 3
6 31999787 Hydrocarboxylic acid receptor 1 in BAT regulates glucose uptake in mice fed a high-fat diet. 2020 3
7 32071396 The lactate receptor GPR81 promotes breast cancer growth via a paracrine mechanism involving antigen-presenting cells in the tumor microenvironment. 2020 Apr 7
8 32200679 Endothelin-1 Mediates the Systemic and Renal Hemodynamic Effects of GPR81 Activation. 2020 May 2
9 32669546 Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling. 2020 Jul 15 2
10 32848615 Effects of Lactate on One Class of Group III (CT3) Muscle Afferents. 2020 1
11 32899645 The Lactate Receptor HCA1 Is Present in the Choroid Plexus, the Tela Choroidea, and the Neuroepithelial Lining of the Dorsal Part of the Third Ventricle. 2020 Sep 4 1
12 33284607 Dietary Lactate Supplementation Protects against Obesity by Promoting Adipose Browning in Mice. 2020 Dec 16 3
13 30884529 Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation. 2019 Mar 1 5
14 30926749 The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of Gα and Gβγ Subunits. 2019 Jun 5 6
15 31220454 Müller Cell-Localized G-Protein-Coupled Receptor 81 (Hydroxycarboxylic Acid Receptor 1) Regulates Inner Retinal Vasculature via Norrin/Wnt Pathways. 2019 Sep 5
16 29386257 GPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis. 2018 Mar 1 2
17 30424795 Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma. 2018 Nov 13 1
18 30543778 Microbiota-Derived Lactate Accelerates Intestinal Stem-Cell-Mediated Epithelial Development. 2018 Dec 12 1
19 27615440 Lactate produced during labor modulates uterine inflammation via GPR81 (HCA1). 2017 Jan 9
20 28534495 Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1. 2017 May 23 1
21 28978803 Involvement of the metabolic sensor GPR81 in cardiovascular control. 2017 Oct 5 1
22 27846210 Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner. 2016 7
23 25495836 Inhibition of G protein-coupled receptor 81 (GPR81) protects against ischemic brain injury. 2015 Mar 4
24 24486398 Identification of a novel GPR81-selective agonist that suppresses lipolysis in mice without cutaneous flushing. 2014 Mar 15 3
25 24657625 Lactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunity. 2014 Jun 3
26 22434674 3,5-Dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. 2012 Jun 1
27 22842580 Effects of high fat diet on GPR109A and GPR81 gene expression. 2012 Aug 24 1
28 21751047 Inflammation inhibits GPR81 expression in adipose tissue. 2011 Oct 1
29 20374963 An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81. 2010 Apr 7 3
30 19047060 Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81. 2009 Jan 30 6