Dinoprostone

prostaglandin E receptor 4 (subtype EP4) ; Mus musculus







227 Article(s)
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151 20470757 PGE2 inhibits natural killer and gamma delta T cell cytotoxicity triggered by NKR and TCR through a cAMP-mediated PKA type I-dependent signaling. 2010 Sep 15 1
152 20483760 The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity. 2010 Jun 15 1
153 20566843 Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis. 2010 Jul 6 1
154 20633531 Promotion of interferon-gamma production by natural killer cells via suppression of murine peritoneal macrophage prostaglandin E₂ production using intravenous anesthetic propofol. 2010 Oct 1
155 20671216 A maladaptive role for EP4 receptors in podocytes. 2010 Oct 4
156 20857620 Prostaglandin EP receptors and their roles in mucosal protection and ulcer healing in the gastrointestinal tract. 2010 5
157 19023895 Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation. 2009 Jun 1
158 19157987 Roles of prostaglandin E receptors in stress responses. 2009 Feb 1
159 19344793 Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice. 2009 Jul 1
160 19407341 Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor. 2009 Jul 3 1
161 19419302 PGE2 signaling through the EP4 receptor on fibroblasts upregulates RANKL and stimulates osteolysis. 2009 Oct 3
162 19628768 Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4. 2009 Aug 1
163 19881295 Phosphodiesterase 3 and 4 negatively regulate receptor activator of nuclear factor-kappaB ligand-mediated osteoclast formation by prostaglandin E2. 2009 Nov 1
164 19923455 Matrix metalloproteinase (MMP)-1 and MMP-3 induce macrophage MMP-9: evidence for the role of TNF-alpha and cyclooxygenase-2. 2009 Dec 15 1
165 18045572 Prostaglandin E2 inhibits mineralization and enhances matrix metalloproteinase-13 in mature cementoblasts mainly via the EP4 pathway. 2008 Mar 3
166 18270204 Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activation. 2008 Apr 11 5
167 18406186 Effect of deletion of the prostaglandin EP2 receptor on the anabolic response to prostaglandin E2 and a selective EP2 receptor agonist. 2008 Jun 1
168 18410593 Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease. 2008 May 1
169 18787774 PGE2-receptor subtype EP4-dependent adherence of mastocytoma P-815 cells to matrix components in subcutaneous tissues overlaying inside surface of air pouch cavity in CDF1 mouse. 2008 Aug 1
170 18815228 Essential role of EP3 subtype in prostaglandin E2-induced adhesion of mouse cultured and peritoneal mast cells to the Arg-Gly-Asp-enriched matrix. 2008 Nov 1
171 17008451 The prevention of colitis by E Prostanoid receptor 4 agonist through enhancement of epithelium survival and regeneration. 2007 Jan 2
172 17075575 Prostaglandin E2 is required for ultraviolet B-induced skin inflammation via EP2 and EP4 receptors. 2007 Jan 2
173 17199550 Cyclooxygenase-2-dependent prostaglandin E(2) upregulates interleukin (IL)-1alpha-induced IL-6 generation in mouse cementoblasts. 2007 Jan 1
174 17332329 Cyclooxygenase-2 inhibits UVB-induced apoptosis in mouse skin by activating the prostaglandin E2 receptors, EP2 and EP4. 2007 Mar 1 1
175 17401137 Prostaglandin E2-EP4 receptor promotes endothelial cell migration via ERK activation and angiogenesis in vivo. 2007 Jun 8 2
176 17585336 Activation of PKA and phosphorylation of sodium-dependent vitamin C transporter 2 by prostaglandin E2 promote osteoblast-like differentiation in MC3T3-E1 cells. 2007 Oct 2
177 17635857 Prostaglandin E2 induces vascular relaxation by E-prostanoid 4 receptor-mediated activation of endothelial nitric oxide synthase. 2007 Sep 3
178 17890674 PGE2 activates cementoclastogenesis by cementoblasts via EP4. 2007 Oct 1
179 19847955 Roles of cyclooxygenase-2 and prostaglandin E receptors in gastric mucosal defense in Helicobacter pylori-infected mice. 2007 Jun 1
180 16338931 Targeting prostaglandin E2 receptors as an alternative strategy to block cyclooxygenase-2-dependent extracellular matrix-induced matrix metalloproteinase-9 expression by macrophages. 2006 Feb 10 2
181 16519664 The opioid peptide nociceptin/orphanin FQ mediates prostaglandin E2-induced allodynia, tactile pain associated with nerve injury. 2006 Feb 1
182 16766399 Ocular inflammatory responses in the EP2 and EP4 receptor knockout mice. 2006 Jun 1
183 16997129 Activation of prostaglandin E receptor EP4 subtype suppresses food intake in mice. 2006 Oct 3
184 17175225 Protective effect of prostaglandin E2 receptors EP2 and EP4 in alloimmune response in vivo. 2006 Dec 2
185 15619665 SC-19220, antagonist of prostaglandin E2 receptor EP1, inhibits osteoclastogenesis by RANKL. 2005 Jan 1
186 15647289 Prostaglandin E2 enhances osteoclastic differentiation of precursor cells through protein kinase A-dependent phosphorylation of TAK1. 2005 Mar 25 2
187 15813989 Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins. 2005 Jan 17 1
188 15834134 Prostaglandin E2 receptors EP2 and EP4 are down-regulated during differentiation of mouse osteoclasts from their precursors. 2005 Jun 24 2
189 15869929 Osteopenia and impaired fracture healing in aged EP4 receptor knockout mice. 2005 Jul 1
190 15976003 Dominant role of prostaglandin E2 EP4 receptor in furosemide-induced salt-losing tubulopathy: a model for hyperprostaglandin E syndrome/antenatal Bartter syndrome. 2005 Aug 1
191 16108069 Significance and therapeutic potential of prostaglandin E2 receptor in hepatic ischemia/reperfusion injury in mice. 2005 Sep 1
192 16185283 Differential expression of E prostanoid receptors in murine and human non-melanoma skin cancer. 2005 Oct 2
193 16189372 Evaluation of selective prostaglandin E2 (PGE2) receptor agonists as therapeutic agents for the treatment of asthma. 2005 Sep 27 2
194 15113745 Stimulation of renin release by prostaglandin E2 is mediated by EP2 and EP4 receptors in mouse kidneys. 2004 Sep 1
195 15123528 Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4. 2004 May 25 2
196 15123663 Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation. 2004 Jul 9 1
197 15127302 PGE2 stimulates Cl- secretion in murine M-1 cortical collecting duct cells in an autocrine manner. 2004 Jul 1
198 15336550 Microarray evaluation of EP4 receptor-mediated prostaglandin E2 suppression of 3T3-L1 adipocyte differentiation. 2004 Sep 24 2
199 12740571 Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells. 2003 Jun 2
200 14569157 [Pathophysiological roles of the prostanoids in the cardiovascular system: studies using mice deficient in prostanoid receptors]. 2003 Nov 1