Dinoprostone

prostaglandin E receptor 4 (subtype EP4) ; Mus musculus







227 Article(s)
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51 27734267 Anti-Inflammatory and Neuroprotective Effects of PGE2 EP4 Signaling in Models of Parkinson's Disease. 2017 Jun 1
52 27797821 Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium. 2017 Jan 4 3
53 27864128 Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice. 2017 Feb 1
54 28062696 Prostaglandin E2 Inhibition of IL-27 Production in Murine Dendritic Cells: A Novel Mechanism That Involves IRF1. 2017 Feb 15 1
55 28086956 Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide. 2017 Jan 5 4
56 28104442 Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis. 2017 Apr 10 1
57 28281561 EP2 receptor antagonism reduces peripheral and central hyperalgesia in a preclinical mouse model of endometriosis. 2017 Mar 10 1
58 28341741 Endogenous prostaglandin E2 amplifies IL-33 production by macrophages through an E prostanoid (EP)2/EP4-cAMP-EPAC-dependent pathway. 2017 May 19 2
59 28432343 COX-1/PGE2/EP4 alleviates mucosal injury by upregulating β-arr1-mediated Akt signaling in colitis. 2017 Apr 21 2
60 28438981 Acute inflammation reveals GABAA receptor-mediated nociception in mouse dorsal root ganglion neurons via PGE2 receptor 4 signaling. 2017 Apr 2
61 28465762 Paricalcitol Pretreatment Attenuates Renal Ischemia-Reperfusion Injury via Prostaglandin E2 Receptor EP4 Pathway. 2017 1
62 28592915 Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE2 and Cytokines. 2017 1
63 28604806 Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf. 2017 1
64 28611444 EP4 inhibition attenuates the development of diabetic and non-diabetic experimental kidney disease. 2017 Jun 13 1
65 28872079 [Mechanisms for the regulatory effect of prostaglandin E2/prostaglandin E receptor 4 on high mobility group box-1 protein in lipopolysaccharide-induced sepsis in mouse peritoneal macrophage]. 2017 Aug 28 1
66 28918839 Prostaglandin E2 Induces Prorenin-Dependent Activation of (Pro)renin Receptor and Upregulation of Cyclooxygenase-2 in Collecting Duct Cells. 2017 Sep 1
67 28920002 EP4 Antagonism by E7046 diminishes Myeloid immunosuppression and synergizes with Treg-reducing IL-2-Diphtheria toxin fusion protein in restoring anti-tumor immunity. 2017 3
68 26189370 Prostaglandin E2-EP4 signaling persistently amplifies CD40-mediated induction of IL-23 p19 expression through canonical and non-canonical NF-κB pathways. 2016 Mar 3
69 26543101 Microsomal Prostaglandin E Synthase-1-Derived PGE2 Inhibits Vascular Smooth Muscle Cell Calcification. 2016 Jan 1
70 26639895 Role of EP2 and EP4 receptors in airway microvascular leak induced by prostaglandin E2. 2016 Mar 5
71 26989254 Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis. 2016 Mar 18 1
72 27032908 The prostaglandin E2/EP4 receptor/cyclic AMP/T-type Ca(2+) channel pathway mediates neuritogenesis in sensory neuron-like ND7/23 cells. 2016 Mar 2
73 27190998 Prostaglandin E Receptor Subtype 4 Signaling in the Heart: Role in Ischemia/Reperfusion Injury and Cardiac Hypertrophy. 2016 5
74 27245461 Vascular Smooth Muscle-Specific EP4 Receptor Deletion in Mice Exacerbates Angiotensin II-Induced Renal Injury. 2016 Oct 20 4
75 27298516 An EP2 Agonist Facilitates NMDA-Induced Outward Currents and Inhibits Dendritic Beading through Activation of BK Channels in Mouse Cortical Neurons. 2016 2
76 27351842 Myeloid Cell Prostaglandin E2 Receptor EP4 Modulates Cytokine Production but Not Atherogenesis in a Mouse Model of Type 1 Diabetes. 2016 7
77 27450806 Abrogation of prostaglandin E-EP4 signaling in osteoblasts prevents the bone destruction induced by human prostate cancer metastases. 2016 Sep 9 1
78 27502370 Prostaglandin E2 Reduces Cardiac Contractility via EP3 Receptor. 2016 Aug 2
79 27664754 The EP1/EP3 receptor agonist 17-pt-PGE2 acts as an EP4 receptor agonist on endothelial barrier function and in a model of LPS-induced pulmonary inflammation. 2016 Dec 1
80 28955904 Prostaglandin E2 facilitates subcellular translocation of the EP4 receptor in neuroectodermal NE-4C stem cells. 2016 Sep 9
81 25110149 Cerebral ischemia increases bone marrow CD4+CD25+FoxP3+ regulatory T cells in mice via signals from sympathetic nervous system. 2015 Jan 1
82 25205726 Mechanisms for proteinase-activated receptor 1-triggered prostaglandin E2 generation in mouse osteoblastic MC3T3-E1 cells. 2015 Feb 1
83 25510249 Activation of prostaglandin E2-EP4 signaling reduces chemokine production in adipose tissue. 2015 Feb 6
84 25669961 Antagonist of prostaglandin E2 receptor 4 induces metabolic alterations in liver of mice. 2015 Mar 6 1
85 25757564 Prostaglandin E2 transactivates the colony-stimulating factor-1 receptor and synergizes with colony-stimulating factor-1 in the induction of macrophage migration via the mitogen-activated protein kinase ERK1/2. 2015 Jun 1
86 25785867 Prostaglandin E2 promotes proliferation of skeletal muscle myoblasts via EP4 receptor activation. 2015 3
87 26100911 Disruption of prostaglandin E2 receptor EP4 impairs urinary concentration via decreasing aquaporin 2 in renal collecting ducts. 2015 Jul 7 1
88 26103450 Activation of EP4 receptors prevents endotoxin-induced neutrophil infiltration into the airways and enhances microvascular barrier function. 2015 Sep 1
89 26118414 Endogenous prostaglandin E2 potentiates anti-inflammatory phenotype of macrophage through the CREB-C/EBP-β cascade. 2015 Sep 1
90 26121313 Prostaglandin E2 increases proximal tubule fluid reabsorption, and modulates cultured proximal tubule cell responses via EP1 and EP4 receptors. 2015 Sep 5
91 26228894 Prostaglandin E-mediated molecular mechanisms driving remodeling of the ductus arteriosus. 2015 Oct 2
92 26308623 The Prostaglandin E2 Receptor EP4 Regulates Obesity-Related Inflammation and Insulin Sensitivity. 2015 1
93 26312751 Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair. 2015 1
94 26378024 Prostaglandin E receptor 4 (EP4) promotes colonic tumorigenesis. 2015 Oct 20 2
95 26400926 Skin-Derived Mesenchymal Stem Cells Alleviate Atherosclerosis via Modulating Macrophage Function. 2015 Nov 1
96 23929707 Mesenchymal stem cells alleviate bacteria-induced liver injury in mice by inducing regulatory dendritic cells. 2014 Feb 1
97 24146253 Prostaglandin E2 inhibits elastogenesis in the ductus arteriosus via EP4 signaling. 2014 Jan 28 1
98 24284792 Prostaglandin E2 induces chloride secretion through crosstalk between cAMP and calcium signaling in mouse inner medullary collecting duct cells. 2014 Feb 1 5
99 24355567 PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis. 2014 Feb 15 2
100 24418675 BMP-2 induces ATF4 phosphorylation in chondrocytes through a COX-2/PGE2 dependent signaling pathway. 2014 Mar 3