olaparib

breast cancer 1, early onset ; Mus musculus







18 Article(s)
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1 35406579 Combinations of ATR, Chk1 and Wee1 Inhibitors with Olaparib Are Active in Olaparib Resistant Brca1 Proficient and Deficient Murine Ovarian Cells. 2022 Apr 1 4
2 33767581 Preclinical evaluation of radiation therapy of BRCA1-associated mammary tumors using a mouse model. 2021 1
3 33984694 PARP inhibitor olaparib has a potential to increase the effectiveness of electrochemotherapy in BRCA1 mutated breast cancer in mice. 2021 Aug 1
4 34126369 Corrigendum to "PARP inhibitor olaparib has a potential to increase the effectiveness of electrochemotherapy in BRCA1 mutated breast cancer in mice" [Bioelectrochemistry 2021 (140) 107832]. 2021 Oct 1
5 34504648 Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status. 2021 Aug 31 2
6 32134529 Olaparib and enzalutamide synergistically suppress HCC progression via the AR-mediated miR-146a-5p/BRCA1 signaling. 2020 Apr 3
7 32218813 Pharmacological ascorbate induces 'BRCAness' and enhances the effects of Poly(ADP-Ribose) polymerase inhibitors against BRCA1/2 wild-type ovarian cancer. 2020 Apr 1
8 32368391 CDK9 inhibitor CDKI-73 is synergetic lethal with PARP inhibitor olaparib in BRCA1 wide-type ovarian cancer. 2020 1
9 32444694 Combined PARP and ATR inhibition potentiates genome instability and cell death in ATM-deficient cancer cells. 2020 Jun 1
10 32546644 Functional Categorization of BRCA1 Variants of Uncertain Clinical Significance in Homologous Recombination Repair Complementation Assays. 2020 Sep 1 1
11 32604417 The PARP inhibitor, olaparib, depletes the ovarian reserve in mice: implications for fertility preservation. 2020 Aug 1 1
12 30414739 Cyclin D1 silencing impairs DNA double strand break repair, sensitizes BRCA1 wildtype ovarian cancer cells to olaparib. 2019 Jan 1
13 30025822 Radiosensitization by the PARP inhibitor olaparib in BRCA1-proficient and deficient high-grade serous ovarian carcinomas. 2018 Sep 3
14 27943283 Prophylactic window therapy with the clinical poly(ADP-ribose) polymerase inhibitor olaparib delays BRCA1-deficient mammary tumour formation in mice. 2017 Mar 1
15 28069724 Synthetic Lethality Exploitation by an Anti-Trop-2-SN-38 Antibody-Drug Conjugate, IMMU-132, Plus PARP Inhibitors in BRCA1/2-wild-type Triple-Negative Breast Cancer. 2017 Jul 1 2
16 27323902 A phase I followed by a randomized phase II trial of two cycles carboplatin-olaparib followed by olaparib monotherapy versus capecitabine in BRCA1- or BRCA2-mutated HER2-negative advanced breast cancer as first line treatment (REVIVAL): study protocol for a randomized controlled trial. 2016 Jun 21 1
17 27498558 Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies. 2016 Aug 8 1
18 22759740 Poly (ADP-ribose) polymerase inhibitors: on the horizon of tailored and personalized therapies for epithelial ovarian cancer. 2012 Sep 1