5 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 35194903 | XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA. | 2022 May | 2 |
2 | 31669203 | PARP1 blockade is synthetically lethal in XRCC1 deficient sporadic epithelial ovarian cancers. | 2020 Jan 28 | 1 |
3 | 33425022 | XRCC1 deficient triple negative breast cancers are sensitive to ATR, ATM and Wee1 inhibitor either alone or in combination with olaparib. | 2020 | 1 |
4 | 27559053 | Drug-Driven Synthetic Lethality: Bypassing Tumor Cell Genetics with a Combination of AsiDNA and PARP Inhibitors. | 2017 Feb 15 | 1 |
5 | 24770870 | Base excision repair defects invoke hypersensitivity to PARP inhibition. | 2014 Aug | 1 |