Irinotecan

RAD50 double strand break repair protein ; Homo sapiens







4 Article(s)
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1 29340025 The novel ATM inhibitor (AZ31) enhances antitumor activity in patient derived xenografts that are resistant to irinotecan monotherapy. 2017 Dec 19 1
2 24934408 Synthetic lethality in ATM-deficient RAD50-mutant tumors underlies outlier response to cancer therapy. 2014 Sep 1
3 25185187 RADical response puts an exceptional responder in CHKmate: a synthetic lethal curative response to DNA-damaging chemotherapy? 2014 Sep 1
4 18941461 Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines. 2008 Nov 18 1