Cysteine

ret proto-oncogene ; Homo sapiens







151 Article(s)
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Pub. Year
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51 12095936 Molecular mechanisms of RET activation in human cancer. 2002 Jun 1
52 12168961 Prophylactic thyroidectomy in MEN 2A syndrome: experience in a single center. 2002 Aug 1
53 11245446 Increased in vivo phosphorylation of ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2B. 2001 Feb 15 1
54 11280716 A large family with hereditary MTC: role of RET genetic analysis in differential diagnosis between MEN 2A and FMTC. 2001 Jan 2
55 11314023 Expression and alternative splicing of c-ret RNA in papillary thyroid carcinomas. 2001 Feb 15 1
56 11331212 Presentation of a kindred with familial medullary thyroid carcinoma and Cys611Phe mutation of the RET proto-oncogene demonstrating low grade malignancy. 2001 May 1
57 11338505 [Molecular diagnosis of multiple type 2 endocrine neoplasia]. 2001 1
58 11386462 A family of multiple endocrine neoplasia type 2A with the RET proto-oncogene mutation in codon 618 (Cys-->Arg). 2001 Apr 2
59 11491658 Osmotic stress-mediated activation of RET kinases involves intracellular disulfide-bonded dimer formation. 2001 Jun 2
60 11564708 Inhibition of Ret oncogene activity by the protein tyrosine phosphatase SHP1. 2001 Oct 1
61 11564857 The sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis. 2001 Oct 9
62 12182058 [Proto-oncogene RET somatic mutations in medullary thyroid carcinoma]. 2001 1
63 10637293 Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases. 2000 Jan 2
64 10879045 [Mechanism of carcinogenesis by germline mutation of protooncogene in hereditary tumors]. 2000 Jun 1
65 10918602 A novel type of mutation in the cysteine rich domain of the RET receptor causes ligand independent activation. 2000 Jul 13 3
66 10982477 Familial form of hirschsprung disease: nucleotide sequence studies reveal point mutations in the RET proto-oncogene in two of six families but not in other candidate genes. 2000 Sep 4 1
67 11213488 Molecular mechanism of activation and superactivation of Ret tyrosine kinases by ultraviolet light irradiation. 2000 Winter 8
68 9950371 High prevalence of the C634Y mutation in the RET proto-oncogene in MEN 2A families in Spain. 1999 Jan 4
69 10049754 Mechanism of Ret activation by a mutation at aspartic acid 631 identified in sporadic pheochromocytoma. 1999 Feb 24 3
70 10091505 [Ret-protooncogene mutation, verified by molecular genetic methods, in a Hungarian MEN Type 2a family]. 1999 Feb 14 1
71 10323403 A novel 9-base pair duplication in RET exon 8 in familial medullary thyroid carcinoma. 1999 May 2
72 10442282 [A case of multiple endocrine neoplasia type 2A (MEN2A) with a mutation in the RET gene]. 1999 Jun 1
73 10484798 Familial medullary thyroid carcinoma: presymptomatic diagnosis and management in children. 1999 Sep 1
74 10490816 The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein. 1999 Aug 26 3
75 10549772 Mutational analysis of the RET proto-oncogene in a kindred with multiple endocrine neoplasia type 2A and Hirschsprung's disease. 1999 Oct 2
76 10628190 [Molecular genetic study of medullary thyroid cancer]. 1999 Dec 5 2
77 9384613 Hirschsprung disease in MEN 2A: increased spectrum of RET exon 10 genotypes and strong genotype-phenotype correlation. 1998 Jan 7
78 9452046 Cys 634 mutations in the RET proto-oncogene in Spanish families affected by MEN 2A. 1998 2
79 9452064 Duplication of 9 base pairs in the critical cysteine-rich domain of the RET proto-oncogene causes multiple endocrine neoplasia type 2A. 1998 1
80 9539934 Molecular diagnosis of multiple endocrine neoplasia type 2A. 1998 Jan 1
81 9587071 27-bp deletion in the ret proto-oncogene as a somatic mutation associated with medullary thyroid carcinoma. 1998 Apr 2
82 9589057 [Genetic testing for ret mutation for early diagnosis and treatment in familial medullary thyroid carcinoma: a case report]. 1998 Apr 1
83 9620546 Full activation of MEN2B mutant RET by an additional MEN2A mutation or by ligand GDNF stimulation. 1998 May 7 1
84 9621513 Mutational analysis of the RET proto-oncogene in 71 Japanese patients with medullary thyroid carcinoma. 1998 2
85 9681851 Molecular mechanisms of development of multiple endocrine neoplasia 2 by RET mutations. 1998 Jun 3
86 9681852 Association of multiple endocrine neoplasia type 2 and Hirschsprung disease. 1998 Jun 3
87 9745455 Molecular analysis of the ret and GDNF genes in a family with multiple endocrine neoplasia type 2A and Hirschsprung disease. 1998 Sep 1
88 9748280 RGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily. 1998 Oct 2 1
89 9794240 RET cooperates with RB/p53 inactivation in a somatic multi-step model for murine thyroid cancer. 1998 Sep 24 1
90 9879991 Dual effect on the RET receptor of MEN 2 mutations affecting specific extracytoplasmic cysteines. 1998 Dec 3 6
91 9881906 Mutations of ret proto-oncogene in 3 Korean families with MEN 2A: clinical use of new restriction sites for genetic diagnosis. 1998 Aug 2
92 10027003 Mechanisms of development of multiple endocrine neoplasia type 2 and Hirschsprung's disease by ret mutations. 1998 4
93 10640177 First continuous human pheochromocytoma cell line: KNA. Biological, cytogenetic and molecular characterization of KNA cells. 1998 Mar 1
94 9012462 The different RET-activating capability of mutations of cysteine 620 or cysteine 634 correlates with the multiple endocrine neoplasia type 2 disease phenotype. 1997 Feb 1 8
95 9096326 The core domain of a new retina specific RGS protein stimulates the GTPase activity of transducin in vitro. 1997 Apr 1 1
96 9096393 Development of medullary thyroid carcinoma in transgenic mice expressing the RET protooncogene altered by a multiple endocrine neoplasia type 2A mutation. 1997 Apr 1 1
97 9097963 A duplication of 12 bp in the critical cysteine rich domain of the RET proto-oncogene results in a distinct phenotype of multiple endocrine neoplasia type 2A. 1997 Apr 4
98 9111993 A Cys634Gly substitution of the RET proto-oncogene in a family with recurrence of multiple endocrine neoplasia type 2A and cutaneous lichen amyloidosis. 1997 Feb 1
99 9150704 Molecular analysis of the RET proto-oncogene in patients with sporadic medullary thyroid carcinoma: a novel point mutation in the extracellular cysteine-rich domain. 1997 Apr 1
100 9160884 A complex nine base pair deletion in RET exon 11 common in sporadic medullary thyroid carcinoma. 1997 May 1 1