Amides

dipeptidyl peptidase 4 ; Homo sapiens







33 Article(s)
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1 34702509 Sensing and imaging of exosomal CD26 secreted from cancer cells and 3D colorectal tumor model using a novel near-infrared fluorogenic probe. 2021 Nov 1
2 31640932 Optimization of the benzamide fragment targeting the S2' site leads to potent dipeptidyl peptidase-IV inhibitors. 2020 Jan 4
3 28040864 GLP-1 receptor independent pathways: emerging beneficial effects of GLP-1 breakdown products. 2017 Jun 2
4 28194113 Cardiovascular Benefits of Native GLP-1 and its Metabolites: An Indicator for GLP-1-Therapy Strategies. 2017 2
5 25482888 DPP-4 inhibitors: a patent review (2012 - 2014). 2015 Feb 2
6 25620096 Dipeptidyl-peptidase IV (DPP IV/CD26)-activated prodrugs: a successful strategy for improving water solubility and oral bioavailability. 2015 2
7 24056839 In vitro metabolism of the glucagon-like peptide-1 (GLP-1)-derived metabolites GLP-1(9-36)amide and GLP-1(28-36)amide in mouse and human hepatocytes. 2013 Dec 6
8 22307932 Dipeptidyl peptidase IV (DPPIV/CD26)-based prodrugs of hydroxy-containing drugs. 2012 Apr 3
9 22650224 Non-insulin injectable treatments (glucagon-like peptide-1 and its analogs) and cardiovascular disease. 2012 Jun 1
10 23094100 Allosteric modulation of the activity of the glucagon-like peptide-1 (GLP-1) metabolite GLP-1 9-36 amide at the GLP-1 receptor. 2012 1
11 20018525 Insulin-like actions of glucagon-like peptide-1: a dual receptor hypothesis. 2010 Feb 2
12 20075143 DPP-4 inhibition by sitagliptin improves the myocardial response to dobutamine stress and mitigates stunning in a pilot study of patients with coronary artery disease. 2010 Mar 1
13 20684603 Discovery of 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors. 2010 Aug 12 1
14 21361038 [Design, synthesis and in vitro activity of glycinamide-bearing compounds as DPP-IV inhibitors]. 2010 Nov 2
15 19833514 The design of potent and selective inhibitors of DPP-4: optimization of ADME properties by amide replacements. 2009 Nov 15 1
16 17904681 Decreased dipeptidyl peptidase-IV activity and glucagon-like peptide-1(7-36)amide degradation in type 2 diabetic subjects. 2008 Jan 1
17 18600568 From the bench to the bedside: dipeptidyl peptidase IV inhibitors, a new class of oral antihyperglycemic agents. 2008 Jul 2
18 17675255 Efficient conversion of tetrapeptide-based TSAO prodrugs to the parent drug by dipeptidyl-peptidase IV (DPPIV/CD26). 2007 Nov 1
19 16332437 Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors. 2006 Mar 1 1
20 16913724 Design and discovery of a novel dipeptidyl-peptidase IV (CD26)-based prodrug approach. 2006 Aug 24 3
21 16919457 Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors. 2006 Oct 15 1
22 15728907 Orally active antiviral tripeptide glycyl-prolyl-glycinamide is activated by CD26 (dipeptidyl peptidase IV) before transport across the intestinal epithelium. 2005 Mar 2
23 15863311 Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors. 2005 May 16 1
24 15908206 Discovery of potent and selective orally bioavailable beta-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors. 2005 Jun 15 1
25 14767880 Lys9 for Glu9 substitution in glucagon-like peptide-1(7-36)amide confers dipeptidylpeptidase IV resistance with cellular and metabolic actions similar to those of established antagonists glucagon-like peptide-1(9-36)amide and exendin (9-39). 2004 Feb 1
26 15012592 N-terminal His(7)-modification of glucagon-like peptide-1(7-36) amide generates dipeptidyl peptidase IV-stable analogues with potent antihyperglycaemic activity. 2004 Mar 2
27 15655705 Circulation and degradation of GIP and GLP-1. 2004 Nov-Dec 1
28 12675225 Different inhibition mechanisms of dipeptidyl peptidase IV by tryptophan containing peptides and amides. 2003 1
29 14664713 Novel dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1(7-36)amide have preserved biological activities in vitro conferring improved glucose-lowering action in vivo. 2003 Dec 1
30 10512614 NVP-DPP728 (1-[[[2-[(5-cyanopyridin-2-yl)amino]ethyl]amino]acetyl]-2-cyano-(S)- pyrrolidine), a slow-binding inhibitor of dipeptidyl peptidase IV. 1999 Sep 7 1
31 8798518 Investigation of glucose-dependent insulinotropic polypeptide-(1-42) and glucagon-like peptide-1-(7-36) degradation in vitro by dipeptidyl peptidase IV using matrix-assisted laser desorption/ionization-time of flight mass spectrometry. A novel kinetic approach. 1996 Sep 20 1
32 7883856 Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo. 1995 Mar 1
33 8100523 Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum. 1993 Jun 15 3