Xanthine

dipeptidyl peptidase 4 ; Homo sapiens







18 Article(s)
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1 34222724 Linagliptin, A Xanthine-Based Dipeptidyl Peptidase-4 Inhibitor, Ameliorates Experimental Autoimmune Myocarditis. 2021 Jun 1
2 27180612 Pharmacokinetic and pharmacodynamic evaluation of linagliptin for the treatment of type 2 diabetes mellitus, with consideration of Asian patient populations. 2017 Jan 1
3 27560285 Discovery of novel xanthine compounds targeting DPP-IV and GPR119 as anti-diabetic agents. 2016 Nov 29 3
4 29879349 [Synthesis and biological activity of substituted xanthines as DPP-Ⅳ inhibitors]. 2016 Jun 1
5 24481594 Molecular dynamic simulations reveal the mechanism of binding between xanthine inhibitors and DPP-4. 2014 Feb 2
6 25065332 Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor, decreases serum uric acid levels in type 2 diabetic patients partly by suppressing xanthine oxidase activity. 2014 Sep 20 1
7 25756669 More effective DPP4 inhibitors as antidiabetics based on sitagliptin applied QSAR and clinical methods. 2014 3
8 23305140 3D QSAR and docking study of gliptin derivatives as DPP-IV inhibitors. 2013 May 1
9 23358258 Synthesis and biological evaluation of xanthine derivatives on dipeptidyl peptidase 4. 2013 4
10 23748509 Clinical utility of the dipeptidyl peptidase-4 inhibitor linagliptin. 2013 May 1
11 24900744 Integrated Synthesis and Testing of Substituted Xanthine Based DPP4 Inhibitors: Application to Drug Discovery. 2013 Aug 8 1
12 22420306 Linagliptin: a novel methylxanthin based approved dipeptidyl peptidase-4 inhibitor. 2012 Jun 1
13 21916836 Linagliptin: a novel xanthine-based dipeptidyl peptidase-4 inhibitor for treatment of type II diabetes mellitus. 2011 Sep 1
14 19947894 Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes. 2010 Jan 3
15 19426127 Inhibition of dipeptidyl peptidase 4 by BI-1356, a new drug for the treatment of beta-cell failure in type 2 diabetes. 2009 Jun 1
16 18485703 3,5-Dihydro-imidazo[4,5-d]pyridazin-4-ones: a class of potent DPP-4 inhibitors. 2008 Jun 1 1
17 17352678 Aromatic heterocycle-based DPP-IV inhibitors: xanthines and related structural types. 2007 2
18 18052023 8-(3-(R)-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a highly potent, selective, long-acting, and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. 2007 Dec 27 1