saxagliptin

dipeptidyl peptidase 4 ; Homo sapiens







164 Article(s)
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1 33961299 Effects of 27 CYP3A4 protein variants on saxagliptin metabolism in vitro. 2022 Feb 2
2 34841901 Targeting the NOD-Like Receptor Pyrin Domain Containing 3 Inflammasome to Improve Healing of Diabetic Wounds. 2022 Jan 13 1
3 35388920 New enantioselective liquid chromatography method development and validation of dipeptidyl peptidase IV inhibitors using a macrocyclic glycopeptide (vancomycin) chiral stationary phase under polar ionic mode condition. 2022 Jul 2
4 32741073 Dipeptidyl peptidase-4 inhibitor treatment and the risk of bullous pemphigoid and skin-related adverse events: A systematic review and meta-analysis of randomized controlled trials. 2021 Mar 1
5 32809070 Real-world adherence, persistence, and in-class switching during use of dipeptidyl peptidase-4 inhibitors: a systematic review and meta-analysis involving 594,138 patients with type 2 diabetes. 2021 Jan 1
6 33068301 Saxagliptin and vildagliptin lowered albuminuria in patients with diabetes and hypertension independent on glycaemic control. 2021 Mar 1
7 34384428 Impact on decision making framework for medicine purchasing in Chinese public hospital decision-making: determining the value of five dipeptidyl peptidase 4 (DPP-4) inhibitors. 2021 Aug 12 1
8 34484112 Cost-Effectiveness of Dipeptidylpeptidase-4 Inhibitors Added to Metformin in Patients With Type 2 Diabetes in China. 2021 2
9 34737703 Effect of CYP3A4 Inhibitors and Inducers on Pharmacokinetics and Pharmacodynamics of Saxagliptin and Active Metabolite M2 in Humans Using Physiological-Based Pharmacokinetic Combined DPP-4 Occupancy. 2021 2
10 32043288 Adding vitamin D3 to the dipeptidyl peptidase-4 inhibitor saxagliptin has the potential to protect β-cell function in LADA patients: A 1-year pilot study. 2020 Jul 1
11 32587614 From Prediabetes to Type 2 Diabetes Mellitus in Women with Polycystic Ovary Syndrome: Lifestyle and Pharmacological Management. 2020 1
12 32909376 Non-insulin antihyperglycaemic drugs and heart failure: an overview of current evidence from randomized controlled trials. 2020 Sep 10 1
13 32948146 Protective effects of DPP-4 inhibitor on podocyte injury in glomerular diseases. 2020 Sep 18 4
14 32990096 Efficacy and safety of saxagliptin for the treatment of type 2 diabetes mellitus. 2020 Dec 1
15 33001278 The DPP-IV inhibitor saxagliptin promotes the migration and invasion of papillary thyroid carcinoma cells via the NRF2/HO1 pathway. 2020 Oct 1 2
16 33116702 Effect of Saxagliptin, a Dipeptidyl Peptidase 4 Inhibitor, on Non-Alcoholic Fatty Liver Disease. 2020 1
17 33163625 LINAGLIPTIN-INDUCED PANCREATITIS. 2020 Jan-Feb 1
18 30500110 Pharmacokinetic Interaction Study Between Saxagliptin and Omeprazole, Famotidine, or Magnesium and Aluminum Hydroxides Plus Simethicone in Healthy Subjects: An Open-Label Randomized Crossover Study. 2019 May 1
19 30639312 The DPP-4 inhibitor saxagliptin ameliorates ox-LDL-induced endothelial dysfunction by regulating AP-1 and NF-κB. 2019 May 15 1
20 30767126 Cardiovascular Protection with Anti-hyperglycemic Agents. 2019 Jun 2
21 30942641 The protective effects of saxagliptin against lipopolysaccharide (LPS)-induced inflammation and damage in human dental pulp cells. 2019 Dec 2
22 31018682 Dipeptidyl peptidase-4 inhibitors and cardiovascular and renal disease in type 2 diabetes: What have we learned from the CARMELINA trial? 2019 Jul 1
23 31127397 Assessment of Heart Failure in Diabetes Cardiovascular Outcomes Trials: Is What We Are Currently Capturing Adequate? 2019 May 24 1
24 31164243 DPP-4 Inhibitor Dose Selection According to Manufacturer Specifications: A Contemporary Experience From UK General Practice. 2019 Aug 2
25 31275243 DPP-4 Inhibition and the Path to Clinical Proof. 2019 1
26 31308448 Effect of Saxagliptin on Endothelial Function in Patients with Type 2 Diabetes: A Prospective Multicenter Study. 2019 Jul 15 1
27 31364869 Saxagliptin suppresses degradation of type II collagen and aggrecan in primary human chondrocytes: a therapeutic implication in osteoarthritis. 2019 Dec 1
28 31737185 DPP-4 inhibitor saxagliptin ameliorates oxygen deprivation/reoxygenation-induced brain endothelial injury. 2019 3
29 31792328 DPP8 is a novel therapeutic target for multiple myeloma. 2019 Dec 2 1
30 29122893 Prospective Postmarketing Surveillance of Acute Myocardial Infarction in New Users of Saxagliptin: A Population-Based Study. 2018 Jan 1
31 29270818 The influence of anti-hyperglycemic drug therapy on cardiovascular and heart failure outcomes in patients with type 2 diabetes mellitus. 2018 May 2
32 29359260 Clinical impact of oral antidiabetic medications in heart failure patients. 2018 May 1
33 29520964 Type 2 diabetes mellitus and heart failure: a position statement from the Heart Failure Association of the European Society of Cardiology. 2018 May 1
34 29549573 Pharmacovigilance Evaluation of the Association Between DPP-4 Inhibitors and Heart Failure: Stimulated Reporting and Moderation by Drug Interactions. 2018 Apr 2
35 29679391 Cardiovascular effects of sitagliptin - An anti-diabetes medicine. 2018 Jul 1
36 29682682 Molecular and clinical roles of incretin-based drugs in patients with heart failure. 2018 May 1
37 29724198 The synergistic effects of saxagliptin and metformin on CD34+ endothelial progenitor cells in early type 2 diabetes patients: a randomized clinical trial. 2018 May 3 1
38 29807374 [Diabetes Mellitus Type 2: Recent Publications and New Drugs]. 2018 Jun 1
39 29912623 Saxagliptin Upregulates Nesfatin-1 Secretion and Ameliorates Insulin Resistance and Metabolic Profiles in Type 2 Diabetes Mellitus. 2018 Sep 2
40 30249630 Efficacy and tolerability of novel triple combination therapy in drug-naïve patients with type 2 diabetes from the TRIPLE-AXEL trial: protocol for an open-label randomised controlled trial. 2018 Sep 24 1
41 30487758 Saxagliptin but Not Sitagliptin Inhibits CaMKII and PKC via DPP9 Inhibition in Cardiomyocytes. 2018 1
42 33693068 Anti-Diabetic Agents and Heart Failure - Response to the CARMELINA Study. 2018 Dec 11 1
43 27282159 Clinical Pharmacokinetics and Pharmacodynamics of Saxagliptin, a Dipeptidyl Peptidase-4 Inhibitor. 2017 Jan 3
44 27653447 Heart failure outcomes in clinical trials of glucose-lowering agents in patients with diabetes. 2017 Jan 1
45 28176222 Saxagliptin/Dapagliflozin: A Review in Type 2 Diabetes Mellitus. 2017 Mar 1
46 28182722 Hemoglobin glycation index as a useful predictor of therapeutic responses to dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes. 2017 1
47 28228317 Short-term therapy with combination dipeptidyl peptidase-4 inhibitor saxagliptin/metformin extended release (XR) is superior to saxagliptin or metformin XR monotherapy in prediabetic women with polycystic ovary syndrome: a single-blind, randomized, pilot study. 2017 Jan 1
48 28367418 Micro-Environmental Signature of The Interactions between Druggable Target Protein, Dipeptidyl Peptidase-IV, and Anti-Diabetic Drugs. 2017 Apr-Jun 2
49 28407661 Effect of Saxagliptin on Circulating Endothelial Progenitor Cells and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients. 2017 Jun 1
50 28417296 DPP4 inhibitors and cardiovascular outcomes: safety on heart failure. 2017 May 1