Vildagliptin

dipeptidyl peptidase 4 ; Homo sapiens







285 Article(s)
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101 24485397 The dipeptidyl peptidase-4 inhibitor vildagliptin does not affect ex vivo cytokine response and lymphocyte function in patients with type 2 diabetes mellitus. 2014 Mar 1
102 24547938 Vildagliptin, a dipeptidyl peptidase-4 inhibitor, for the treatment of type 2 diabetes. 2014 Apr 3
103 24604395 Efficacy and Safety of Vildagliptin as Add-on to Metformin in Japanese Patients with Type 2 Diabetes Mellitus. 2014 Jun 1
104 24612221 Glucagon dynamics during hypoglycaemia and food-re-challenge following treatment with vildagliptin in insulin-treated patients with type 2 diabetes. 2014 Sep 1
105 24627624 Effect of vildagliptin add-on treatment to metformin on plasma asymmetric dimethylarginine in type 2 diabetes mellitus patients. 2014 2
106 24638989 Vildagliptin: a review of its use in type 2 diabetes mellitus. 2014 Apr 1
107 24640595 Capillary zone electrophoresis for determination of vildagliptin (a DPP-4 inhibitor) in pharmaceutical formulation and comparative study with HPLC. 2014 Feb 1
108 24682379 Efficacy of vildagliptin versus sulfonylureas as add-on therapy to metformin: comparison of results from randomised controlled and observational studies. 2014 Jul 2
109 24802729 Is there an impact of treatment with DPP-4 inhibitors on lymphocyte subpopulations in type 2 diabetic patients? 2014 1
110 24837407 Vildagliptin , a DPP-4 inhibitor for the twice-daily treatment of type 2 diabetes mellitus with or without metformin. 2014 Jun 1
111 24939431 Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes. 2014 Sep 1
112 24977657 The dipeptidyl peptidase-4 inhibitor vildagliptin has the capacity to repair β-cell dysfunction and insulin resistance. 2014 Oct 1
113 25171159 DPP-4 inhibitors: pharmacological differences and their clinical implications. 2014 Sep 1
114 25204760 Dipeptidyl peptidase-4 inhibitor (vildagliptin) improves glycemic control after meal tolerance test by suppressing glucagon release. 2014 Dec 1
115 25411599 Efficacy and safety of nateglinide plus vildagliptin combination therapy compared with switching to vildagliptin in type 2 diabetes patients inadequately controlled with nateglinide. 2014 Jul 1
116 25429228 Changes in body weight after 24 weeks of vildagliptin therapy as a function of fasting glucose levels in patients with type 2 diabetes. 2014 1
117 25597711 [Combination therapy of metformin vs dipeptidulpeptidase inhibitors and sulfonylureas in type 2 diabetes: clinical and economic impact]. 2014 Oct-Dec 1
118 22882290 Studies in rodents with the dipeptidyl peptidase-4 inhibitor vildagliptin to evaluate possible drug-induced pancreatic histological changes that are predictive of pancreatitis and cancer development in man. 2013 Jan 1
119 23318959 Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity. 2013 Jun 1
120 23323612 Dipeptidyl peptidase-4 inhibitors and angioedema: a class effect? 2013 Apr 1
121 23430354 Effects of vildagliptin/metformin therapy on patient-reported outcomes: work productivity, patient satisfaction, and resource utilization. 2013 Feb 1
122 23431062 Clinical evidence and mechanistic basis for vildagliptin's effect in combination with insulin. 2013 2
123 23488656 Effects of vildagliptin versus sitagliptin, on cardiac function, heart rate variability and mitochondrial function in obese insulin-resistant rats. 2013 Jul 1
124 23501107 A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site. 2013 May 3 2
125 23650450 Managing diabetic patients with moderate or severe renal impairment using DPP-4 inhibitors: focus on vildagliptin. 2013 1
126 23659561 Treatment adherence with vildagliptin compared to sulphonylurea as add-on to metformin in Muslim patients with type 2 diabetes mellitus fasting during Ramadan. 2013 Jul 1
127 23707531 Cardiovascular pleiotropic actions of DPP-4 inhibitors: a step at the cutting edge in understanding their additional therapeutic potentials. 2013 Sep 1
128 23711060 [Use of vildagliptin from an internal disease specialists point of view]. 2013 Apr 1
129 23782587 Pharmacokinetic and pharmacodynamic interaction of vildagliptin and voglibose in Japanese patients with Type 2 diabetes. 2013 Aug 3
130 23818788 Profile of vildagliptin in type 2 diabetes: efficacy, safety, and patient acceptability. 2013 1
131 23821355 Experience with vildagliptin in patients ≥75 years with type 2 diabetes and moderate or severe renal impairment. 2013 Dec 1
132 23848558 Cognitive and functional influences of vildagliptin, a DPP-4 inhibitor, added to ongoing metformin therapy in elderly with type 2 diabetes. 2013 Sep 1
133 23990203 Association between urinary albumin excretion and low-density lipoprotein heterogeneity following treatment of type 2 diabetes patients with the dipeptidyl peptidase-4 inhibitor, vildagliptin: a pilot study. 2013 Dec 1
134 24068868 Dipeptidyl peptidase-4 inhibitors in type 2 diabetes therapy--focus on alogliptin. 2013 1
135 24137964 [A combination of dipeptidyl peptidase-4 inhibitor and metformin in the treatment of patients with type 2 diabetes mellitus: effective control of glycemia, weight, and quantitative body composition]. 2013 1
136 24163113 Dipeptidyl peptidase-4 inhibition in patients with type 2 diabetes treated with saxagliptin, sitagliptin, or vildagliptin. 2013 Dec 3
137 24185376 Novel water-soluble prodrugs of acyclovir cleavable by the dipeptidyl-peptidase IV (DPP IV/CD26) enzyme. 2013 4
138 25671081 The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins. 2013 1
139 22051153 Effects of vildagliptin on postprandial markers of bone resorption and calcium homeostasis in recently diagnosed, well-controlled type 2 diabetes patients. 2012 Jun 1
140 22191695 The efficacy and safety of vildagliptin in patients with type 2 diabetes: a meta-analysis of randomized clinical trials. 2012 Aug 1
141 22339447 Clinical pharmacokinetics and pharmacodynamics of vildagliptin. 2012 Mar 1 8
142 22390829 Reply to: Ahren B et al. Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans. Diabetes Obes Metab 2011; 13(9): 775-783 and Ahren B et al. Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin. Diabetes Obes Metab 2011; 13(3): 193-203. 2012 Apr 1
143 22397507 Combination therapy with metformin plus vildagliptin in type 2 diabetes mellitus. 2012 Jun 1
144 22442825 Mechanism-based population modelling of the effects of vildagliptin on GLP-1, glucose and insulin in patients with type 2 diabetes. 2012 Mar 1
145 22442826 Mechanism-based population pharmacokinetic modelling in diabetes: vildagliptin as a tight binding inhibitor and substrate of dipeptidyl peptidase IV. 2012 Mar 6
146 22456294 Effects of meal timing relative to dosing on the pharmacokinetics and pharmacodynamics of vildagliptin in Japanese patients with Type 2 diabetes. 2012 Apr 2
147 22661900 Evidence to support the use of vildagliptin monotherapy in the treatment of type 2 diabetes mellitus. 2012 1
148 22672501 Effects of a vildagliptin/metformin combination on markers of atherosclerosis, thrombosis, and inflammation in diabetic patients with coronary artery disease. 2012 Jun 6 1
149 22686547 Comparative clinical pharmacokinetics of dipeptidyl peptidase-4 inhibitors. 2012 Aug 1 1
150 22690943 One-year safety, tolerability and efficacy of vildagliptin in patients with type 2 diabetes and moderate or severe renal impairment. 2012 Nov 1