pyrazolanthrone

mitogen-activated protein kinase 9 ; Homo sapiens







22 Article(s)
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1 34411914 Tingenone and 22-hydroxytingenone target oxidative stress through downregulation of thioredoxin, leading to DNA double-strand break and JNK/p38-mediated apoptosis in acute myeloid leukemia HL-60 cells. 2021 Oct 1
2 31348577 Stanniocalcin-1 mediates negative regulatory action of epidermal layer on expression of matrix-related genes in dermal fibroblasts. 2019 Nov 2
3 28138710 Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway. 2017 Mar 1
4 27096061 Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes. 2016 Jan 2
5 27580989 Curcumin Suppresses Proliferation and Migration and Induces Apoptosis on Human Placental Choriocarcinoma Cells via ERK1/2 and SAPK/JNK MAPK Signaling Pathways. 2016 Oct 1 2
6 23172806 Apoptosis induced by para-phenylenediamine involves formation of ROS and activation of p38 and JNK in chang liver cells. 2014 Sep 2
7 25198581 mGluR3 promotes proliferation of human embryonic cortical neural progenitor cells by activating ERK1/2 and JNK2 signaling pathway in vitro. 2014 Sep 6 1
8 25435694 Decrease of PKB/Akt Phosphorylation is Partially Mediated by SAPK/JNK Activation in Serum-free L6 Myoblasts Starved with Low Glucose. 2014 Nov 2
9 23624146 Inhibition of SAPK/JNK leads to enhanced IL-1-induced IL-6 synthesis in osteoblasts. 2013 Jul 15 1
10 22870247 Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancer. 2012 1
11 20511679 Studies on molecular mechanisms of growth inhibitory effects of thymoquinone against prostate cancer cells: role of reactive oxygen species. 2010 Jun 1
12 19107874 Oxidative stress resistance through blocking Hsp60 translocation followed by SAPK/JNK inhibition in aged human diploid fibroblasts. 2009 Jan 2
13 19302787 Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress. 2009 Mar 4 2
14 19385049 Concurrent protective and destructive signaling of JNK2 in neuroblastoma cells. 2009 Jun 1
15 19852810 AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis. 2009 Oct 23 2
16 18847500 Downregulation of CD147 expression alters cytoskeleton architecture and inhibits gelatinase production and SAPK pathway in human hepatocellular carcinoma cells. 2008 Oct 11 1
17 16337741 Induction of apoptosis and cell cycle arrest by a specific c-Jun NH2-terminal kinase (JNK) inhibitor, SP-600125, in gastrointestinal cancers. 2006 Sep 28 1
18 16410344 Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts. 2006 Mar 1
19 16979204 Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes. 2006 Nov 15 1
20 15908180 Synergistic activation of JNK/SAPK induced by TNF-alpha and IFN-gamma: apoptosis of pancreatic beta-cells via the p53 and ROS pathway. 2005 Dec 1
21 15113050 Erianin induces a JNK/SAPK-dependent metabolic inhibition in human umbilical vein endothelial cells. 2004 Mar-Apr 1
22 12898508 Jun N-terminal kinase pathway enhances signaling of monocytic differentiation of human leukemia cells induced by 1,25-dihydroxyvitamin D3. 2003 Aug 15 1