gamma-Aminobutyric Acid

glutamate-ammonia ligase (glutamine synthetase) ; Mus musculus







56 Article(s)
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1 34676525 GAD67-mediated GABA Synthesis and Signaling Impinges on Directing Basket Cell Axonal Projections Toward Purkinje Cells in the Cerebellum. 2021 Oct 21 4
2 34702328 Synaptic dysfunction of Aldh1a1 neurons in the ventral tegmental area causes impulsive behaviors. 2021 Oct 26 6
3 31898404 Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory. 2020 Jul 2
4 31178551 Capacitation of mouse sperm is modulated by gamma-aminobutyric acid (GABA) concentration. 2019 Aug 9 3
5 31294445 Loss of Cln5 leads to altered Gad1 expression and deficits in interneuron development in mice. 2019 Oct 1 2
6 30719253 Effects of Jobelyn® on Isoniazid-Induced Seizures, Biomarkers of Oxidative Stress and Glutamate Decarboxylase Activity in Mice. 2018 Nov-Dec 1
7 27662193 Overexpression of Glutamate Decarboxylase in Mesenchymal Stem Cells Enhances Their Immunosuppressive Properties and Increases GABA and Nitric Oxide Levels. 2016 1
8 27705802 Cytosolic Accumulation of L-Proline Disrupts GABA-Ergic Transmission through GAD Blockade. 2016 Oct 4 2
9 25545713 GAD65/GAD67 double knockout mice exhibit intermediate severity in both cleft palate and omphalocele compared with GAD67 knockout and VGAT knockout mice. 2015 Mar 12 3
10 25742870 ¹H- and ¹³C-NMR spectroscopy of Thy-1-APPSL mice brain extracts indicates metabolic changes in Alzheimer's disease. 2015 Apr 2
11 26370162 Gad1 mRNA as a reliable indicator of altered GABA release from orexigenic neurons in the hypothalamus. 2015 Nov 8
12 24682237 Expression of GAD67 and Dlx5 in the taste buds of mice genetically lacking Mash1. 2014 Jun 2
13 25565962 Glutamic acid decarboxylase 67 expression by a distinct population of mouse vestibular supporting cells. 2014 5
14 23486948 Rapid, activity-independent turnover of vesicular transmitter content at a mixed glycine/GABA synapse. 2013 Mar 13 1
15 20664610 Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine. 2011 Feb 4
16 21039523 GAD65 is essential for synthesis of GABA destined for tonic inhibition regulating epileptiform activity. 2010 Dec 2
17 21049022 Expression of GABAergic receptors in mouse taste receptor cells. 2010 Oct 26 6
18 19233937 Altered responses to propofol, but not ketamine, in mice deficient in the 65-kilodalton isoform of glutamate decarboxylase. 2009 May 2
19 19571163 Thermal hyperalgesia via supraspinal mechanisms in mice lacking glutamate decarboxylase 65. 2009 Oct 1
20 17936537 Prenatal hypoxia down regulates the GABA pathway in newborn mice cerebral cortex; partial protection by MgSO4. 2008 Feb 1
21 18384748 GABA and synaptic inhibition of mouse cerebellum lacking glutamate decarboxylase 67. 2008 Jun 6 1
22 17113713 GABA-synthesizing enzyme, GAD67, from dermal fibroblasts: evidence for a new skin function. 2007 Feb 4
23 17482148 Role of glutamate decarboxylase (GAD) isoform, GAD65, in GABA synthesis and transport into synaptic vesicles-Evidence from GAD65-knockout mice studies. 2007 Jun 18 2
24 17849453 Experimental induction of palate shelf elevation in glutamate decarboxylase 67-deficient mice with cleft palate due to vertically oriented palatal shelf. 2007 Oct 2
25 16516347 Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools. 2006 May-Jun 2
26 16573556 Antigen-presenting cells expressing glutamate decarboxylase 67 were identified as epithelial cells in glutamate decarboxylase 67-GFP knock-in mouse thymus. 2006 Mar 2
27 16672340 Multidirectional and multizonal tangential migration of GABAergic interneurons in the developing cerebral cortex. 2006 Jun 1
28 15647480 Relationship of brain-derived neurotrophic factor and its receptor TrkB to altered inhibitory prefrontal circuitry in schizophrenia. 2005 Jan 12 1
29 16270167 Gaba- and serotonin-immunoreactive structures and ca(2+)-binding protein in the neocortex of the reeler mouse mutant. 2005 Nov 2
30 15036622 Altered taste function in mice deficient in the 65-kDa isoform of glutamate decarboxylase. 2004 Feb 19 1
31 15525333 First direct demonstration of extensive GABA synthesis in mouse cerebellar neuronal cultures. 2004 Nov 1
32 15839244 [GABA-, serotonin-immunoreactive structures and Ca2+-binding protein in the neocortex of reeler mutant mice]. 2004 4
33 14534141 Multimodal tangential migration of neocortical GABAergic neurons independent of GPI-anchored proteins. 2003 Dec 2
34 12271488 Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons. 2002 Oct 14 2
35 11178105 Dynamic expression of a glutamate decarboxylase gene in multiple non-neural tissues during mouse development. 2001 4
36 10700583 Region-specific localization of glutamine synthetase immunoreactivity in the mouse olfactory bulb: implications for neuron-glia interaction in bulbar synaptic plasticity. 2000 Feb 28 4
37 10872731 Immunohistochemical studies of the structural bases of inhibition in the central cerebellar nuclei in mice. 2000 Mar-Apr 2
38 10987822 Structure of the mouse glutamate decarboxylase 65 gene and its promoter: preferential expression of its promoter in the GABAergic neurons of transgenic mice. 2000 Oct 2
39 9990087 Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. 1999 Feb 16 2
40 10501472 Synaptic localization of the 67,000 mol. wt isoform of glutamate decarboxylase and transmitter function of GABA in the mouse cerebellum lacking the 65,000 mol. wt isoform. 1999 5
41 9527896 Toxicity of dieldrin for dopaminergic neurons in mesencephalic cultures. 1998 Apr 4
42 9874145 A synthetic standard for competitive RT-PCR quantitation of 13 GABA receptor type A subunit mRNAs in rats and mice. 1998 Nov 1 1
43 9219949 A ventrodorsal GABA gradient in the embryonic retina prior to expression of glutamate decarboxylase. 1997 Aug 4
44 8954733 GABAergic neurons in the embryonic olfactory pit/vomeronasal organ: maintenance of functional GABAergic synapses in olfactory explants. 1996 Dec 15 2
45 7894697 Rapid assay for gamma-aminobutyric acid in mouse brain synaptosomes using gas chromatography-mass spectrometry. 1994 Dec 2 4
46 1458185 [The possible participation of the GABA metabolic system in the mechanisms of the protective action of L-aspartate in hypoxia in an enclosed space]. 1992 Jul-Aug 1
47 2904818 Effects of pharmacological manipulations on basal and newly synthesized levels of GABA, glutamate, aspartate and glutamine in mouse brain cortex. 1988 Dec 1 1
48 2874558 In situ hybridization to localize mRNA encoding the neurotransmitter synthetic enzyme glutamate decarboxylase in mouse cerebellum. 1986 Aug 4
49 6146727 Metabolic fate of [14C]-glutamine in mouse cerebral neurons in primary cultures. 1984 1
50 6151865 Proline, glutamate and glutamine metabolism in mouse brain synaptosomes. 1984 Dec 10 1