Tryptophan

indoleamine 2,3-dioxygenase 1 ; Homo sapiens







1003 Article(s)
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851 17933973 Indoleamine 2,3-dioxygenase gene transfer prolongs cardiac allograft survival. 2007 Dec 3
852 17982903 The immunological basis of glutamatergic disturbance in schizophrenia: towards an integrated view. 2007 1
853 17999277 Effect of Kidney-replenishing herb on the indoleamine 2,3-dioxygenase of human syncytiotrophoblasts cultured in vitro and the balance of helper T-cell cytokines. 2007 Nov 2
854 18026683 Evolution of vertebrate indoleamine 2,3-dioxygenases. 2007 Dec 3
855 18055547 Indoleamine 2,3-dioxygenase (IDO): the antagonist of type I interferon-driven skin inflammation? 2007 Dec 2
856 18056175 Expression of indoleamine 2,3-dioxygenase in tumor endothelial cells correlates with long-term survival of patients with renal cell carcinoma. 2007 Dec 1 1
857 18063923 The immune effects of TRYCATs (tryptophan catabolites along the IDO pathway): relevance for depression - and other conditions characterized by tryptophan depletion induced by inflammation. 2007 Dec 4
858 18077563 Genetic and hormonal regulation of tryptophan kynurenine metabolism: implications for vascular cognitive impairment, major depressive disorder, and aging. 2007 Dec 2
859 18094439 The immunoregulatory function of indoleamine 2, 3 dioxygenase and its application in allotransplantation. 2007 Dec 4
860 16139256 Monitoring tryptophan metabolism in chronic immune activation. 2006 Feb 3
861 16261283 Tryptophan degradation increases with stage in patients with rheumatoid arthritis. 2006 May 1
862 16321356 A fluorescence-based assay for indoleamine 2,3-dioxygenase. 2006 Feb 1 1
863 16365430 Nitration and inactivation of IDO by peroxynitrite. 2006 Jan 1 1
864 16368976 Comparison of gamma interferon-mediated antichlamydial defense mechanisms in human and mouse cells. 2006 Jan 1
865 16385630 Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines. 2006 Feb 2
866 16417228 Local expression of indoleamine 2,3-dioxygenase protects engraftment of xenogeneic skin substitute. 2006 Jan 3
867 16476191 Indoleamine-2,3-dioxygenase modulation of allergic immune responses. 2006 Feb 4
868 16477023 Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase. 2006 Feb 21 2
869 16482510 Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression. 2006 Mar 2
870 16489067 Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells. 2006 Feb 15 2
871 16490253 Regulatory role of tryptophan degradation pathway in HLA-G expression by human monocyte-derived dendritic cells. 2006 Jul 1
872 16513157 Indoleamine 2,3-dioxygenase activity in nonagenarians is markedly increased and predicts mortality. 2006 May 4
873 16522817 CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition. 2006 Jul 1 1
874 16687019 Bariatric surgery cannot prevent tryptophan depletion due to chronic immune activation in morbidly obese patients. 2006 May 3
875 16797727 Bimodal effect of nitric oxide in the enzymatic activity of indoleamine 2,3-dioxygenase in human monocytic cells. 2006 Aug 15 2
876 16834326 Interactions between nitric oxide and indoleamine 2,3-dioxygenase. 2006 Jul 18 6
877 16842443 Low serum tryptophan levels, reduced macrophage IDO activity and high frequency of psychopathology in HCV patients. 2006 Jun 4
878 16896154 CTLA-4 blockade decreases TGF-beta, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques. 2006 Dec 1 1
879 16897708 Inhibitors of human indoleamine 2,3-dioxygenase identified with a target-based screen in yeast. 2006 Mar 3
880 16902152 The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function. 2006 Dec 15 5
881 16907915 The activity of the immunoregulatory enzyme indoleamine 2,3-dioxygenase is decreased in smokers. 2006 Sep 2
882 16931033 NF-kappa B activation contributes to indoleamine dioxygenase transcriptional synergy induced by IFN-gamma and tumor necrosis factor-alpha. 2006 Jul 2
883 16997853 A high-affinity, tryptophan-selective amino acid transport system in human macrophages. 2006 Dec 5
884 17030574 Up-regulation of gamma interferon receptor expression due to Chlamydia-toll-like receptor interaction does not enhance signal transducer and activator of transcription 1 signaling. 2006 Dec 1
885 17062375 Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission. 2006 Oct 3
886 17114500 Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. 2006 Dec 1 2
887 17117179 Indoleamine 2,3-dioxygenase is a novel prognostic indicator for endometrial cancer. 2006 Dec 4 1
888 14624357 Enhancement of antimicrobial effects by glucocorticoids. 2005 Jan 4
889 15466932 Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells. 2005 Feb 15 2
890 15494706 IDO and interferon-alpha-induced depressive symptoms: a shift in hypothesis from tryptophan depletion to neurotoxicity. 2005 Jun 7
891 15684619 The role of IFN-gamma and TNF-alpha-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase. 2005 Jan 2
892 15718917 Enhanced enzymatic degradation of tryptophan by indoleamine 2,3-dioxygenase contributes to the tryptophan-deficient state seen after major trauma. 2005 Mar 6
893 15762873 Aspirin down-regulates tryptophan degradation in stimulated human peripheral blood mononuclear cells in vitro. 2005 Apr 2
894 15853924 Association of interferon-gamma +874(T/A) single nucleotide polymorphism with the rate of tryptophan catabolism in healthy individuals. 2005 Apr 2
895 15896467 Tryptophan degradation in patients with gynecological cancer correlates with immune activation. 2005 Jun 8 2
896 15919929 Indoleamine 2,3-dioxygenase mediates cell type-specific anti-measles virus activity of gamma interferon. 2005 Jun 3
897 15961516 Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. 2005 Oct 1 2
898 15967116 Eosinophil granulocytes account for indoleamine 2,3-dioxygenase-mediated immune escape in human non-small cell lung cancer. 2005 Apr 2
899 16083346 Indoleamine 2,3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors. 2005 Aug 1
900 16113824 Role of human brain microvascular endothelial cells during central nervous system infection. Significance of indoleamine 2,3-dioxygenase in antimicrobial defence and immunoregulation. 2005 Aug 4